GTP-Binding Protein alpha Subunits, G12-G13
"GTP-Binding Protein alpha Subunits, G12-G13" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed family of heterotrimeric GTP-binding protein alpha subunits that signal through interactions with a variety of second messengers as GTPASE-ACTIVATING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; and HEAT SHOCK PROTEINS. The G12-G13 part of the name is also spelled G12/G13.
| Descriptor ID |
D044365
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| MeSH Number(s) |
D08.811.277.040.330.300.200.100.100 D12.644.360.360.100.100 D12.776.157.325.332.100.100 D12.776.476.375.100.100 D12.776.543.325.100.100
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| Concept/Terms |
GTP-Binding Protein alpha Subunits, G12-G13- GTP-Binding Protein alpha Subunits, G12-G13
- GTP Binding Protein alpha Subunits, G12 G13
- G-Protein, G12-G13 alpha Subunits
- G Protein, G12 G13 alpha Subunits
- G-Protein, G12-G13 alpha Family
- G Protein, G12 G13 alpha Family
GTP-Binding Protein alpha Subunit, G13- GTP-Binding Protein alpha Subunit, G13
- GTP Binding Protein alpha Subunit, G13
- G13 G-Protein
- G-Protein, G13
- G13 G Protein
- G(13) Protein
- Galpha13 Protein
- G-Protein, G13 Subunit
- G Protein, G13 Subunit
- G13 Subunit G-Protein
- Subunit G-Protein, G13
- G13 Protein
- G alpha13 Protein
- alpha13 Protein, G
GTP-Binding Protein alpha Subunit, G12- GTP-Binding Protein alpha Subunit, G12
- GTP Binding Protein alpha Subunit, G12
- G12 alpha Protein
- alpha Protein, G12
- G12 Protein
- Protein, G12
- G-Protein, G12 Subunit
- G Protein, G12 Subunit
- G12 Subunit G-Protein
- Subunit G-Protein, G12
- G alpha12 Protein
- alpha12 Protein, G
- Galpha12 Protein
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits, G12-G13".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits, G12-G13".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits, G12-G13" by people in this website by year, and whether "GTP-Binding Protein alpha Subunits, G12-G13" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
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Below are the most recent publications written about "GTP-Binding Protein alpha Subunits, G12-G13" by people in Profiles.
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Ha JH, Ward JD, Varadarajalu L, Kim SG, Dhanasekaran DN. The gep proto-oncogene Ga12 mediates LPA-stimulated activation of CREB in ovarian cancer cells. Cell Signal. 2014 Jan; 26(1):122-32.
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Gardner JA, Ha JH, Jayaraman M, Dhanasekaran DN. The gep proto-oncogene Ga13 mediates lysophosphatidic acid-mediated migration of pancreatic cancer cells. Pancreas. 2013 Jul; 42(5):819-28.
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Yang YM, Lee S, Nam CW, Ha JH, Jayaraman M, Dhanasekaran DN, Lee CH, Kwak MK, Kim SG. G(alpha)12/13 inhibition enhances the anticancer effect of bortezomib through PSMB5 downregulation. Carcinogenesis. 2010 Jul; 31(7):1230-7.
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Radhika V, Hee Ha J, Jayaraman M, Tsim ST, Dhanasekaran N. Mitogenic signaling by lysophosphatidic acid (LPA) involves Galpha12. Oncogene. 2005 Jun 30; 24(28):4597-603.