GTP-Binding Protein alpha Subunits, G12-G13
"GTP-Binding Protein alpha Subunits, G12-G13" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed family of heterotrimeric GTP-binding protein alpha subunits that signal through interactions with a variety of second messengers as GTPASE-ACTIVATING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; and HEAT SHOCK PROTEINS. The G12-G13 part of the name is also spelled G12/G13.
| Descriptor ID |
D044365
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| MeSH Number(s) |
D08.811.277.040.330.300.200.100.100 D12.644.360.360.100.100 D12.776.157.325.332.100.100 D12.776.476.375.100.100 D12.776.543.325.100.100
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| Concept/Terms |
GTP-Binding Protein alpha Subunits, G12-G13- GTP-Binding Protein alpha Subunits, G12-G13
- GTP Binding Protein alpha Subunits, G12 G13
- G-Protein, G12-G13 alpha Subunits
- G Protein, G12 G13 alpha Subunits
- G-Protein, G12-G13 alpha Family
- G Protein, G12 G13 alpha Family
GTP-Binding Protein alpha Subunit, G13- GTP-Binding Protein alpha Subunit, G13
- GTP Binding Protein alpha Subunit, G13
- G13 G-Protein
- G-Protein, G13
- G13 G Protein
- G(13) Protein
- Galpha13 Protein
- G-Protein, G13 Subunit
- G Protein, G13 Subunit
- G13 Subunit G-Protein
- Subunit G-Protein, G13
- G13 Protein
- G alpha13 Protein
- alpha13 Protein, G
GTP-Binding Protein alpha Subunit, G12- GTP-Binding Protein alpha Subunit, G12
- GTP Binding Protein alpha Subunit, G12
- G12 alpha Protein
- alpha Protein, G12
- G12 Protein
- Protein, G12
- G-Protein, G12 Subunit
- G Protein, G12 Subunit
- G12 Subunit G-Protein
- Subunit G-Protein, G12
- G alpha12 Protein
- alpha12 Protein, G
- Galpha12 Protein
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits, G12-G13".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits, G12-G13".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits, G12-G13" by people in this website by year, and whether "GTP-Binding Protein alpha Subunits, G12-G13" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 2 | 0 | 2 |
| 2006 | 2 | 1 | 3 |
| 2008 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTP-Binding Protein alpha Subunits, G12-G13" by people in Profiles.
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Ga12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinoma. Oncogene. 2015 May 28; 34(22):2910-21.
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The gep proto-oncogene Ga12 mediates LPA-stimulated activation of CREB in ovarian cancer cells. Cell Signal. 2014 Jan; 26(1):122-32.
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The gep proto-oncogene Ga13 mediates lysophosphatidic acid-mediated migration of pancreatic cancer cells. Pancreas. 2013 Jul; 42(5):819-28.
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Neoplastic transformation induced by the gep oncogenes involves the scaffold protein JNK-interacting leucine zipper protein. Neoplasia. 2011 Apr; 13(4):358-64.
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G(alpha)12/13 inhibition enhances the anticancer effect of bortezomib through PSMB5 downregulation. Carcinogenesis. 2010 Jul; 31(7):1230-7.
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Endothelial nitric oxide synthase inhibits G12/13 and rho-kinase activated by the angiotensin II type-1 receptor: implication in vascular migration. Arterioscler Thromb Vasc Biol. 2009 Feb; 29(2):217-24.
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Homocysteine effects classical pathway of GPCR down regulation: Galpha(q/11), Galpha(12/13), G(i/o). Mol Cell Biochem. 2009 Jan; 321(1-2):1-8.
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Transducing the signals: a G protein takes a new identity. Sci STKE. 2006 Aug 08; 2006(347):pe31.
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Endodermal differentiation of murine embryonic carcinoma cells by retinoic acid requires JLP, a JNK-scaffolding protein. J Cell Biochem. 2006 Jul 01; 98(4):715-22.
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Transactivation of platelet-derived growth factor receptor alpha by the GTPase-deficient activated mutant of Galpha12. Mol Cell Biol. 2006 Jan; 26(1):50-62.