"Sarcosine Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.
| Descriptor ID |
D050892
|
| MeSH Number(s) |
D08.811.682.662.582.550
|
| Concept/Terms |
Sarcosine Dehydrogenase- Sarcosine Dehydrogenase
- Dehydrogenase, Sarcosine
- Sarcosine N-Demethylase
- N-Demethylase, Sarcosine
- Sarcosine N Demethylase
- Monomethylglycine Dehydrogenase
- Dehydrogenase, Monomethylglycine
|
Below are MeSH descriptors whose meaning is more general than "Sarcosine Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Sarcosine Dehydrogenase".
This graph shows the total number of publications written about "Sarcosine Dehydrogenase" by people in this website by year, and whether "Sarcosine Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sarcosine Dehydrogenase" by people in Profiles.
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TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells. Prostate. 2013 Oct; 73(14):1561-75.
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The tumor suppressor activity of the transmembrane protein with epidermal growth factor and two follistatin motifs 2 (TMEFF2) correlates with its ability to modulate sarcosine levels. J Biol Chem. 2011 May 06; 286(18):16091-100.