Sjogren's Syndrome

"Sjogren's Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

Descriptor ID	D012859
MeSH Number(s)	C05.550.114.154.774 C05.799.114.774 C07.465.815.929.669 C11.496.260.719 C17.300.775.099.774 C20.111.199.774
Concept/Terms	Sjogren's Syndrome Sjogren's Syndrome Sjogrens Syndrome Syndrome, Sjogren's Sjogren Syndrome Sicca Syndrome Sicca Syndrome Syndrome, Sicca

Below are MeSH descriptors whose meaning is more general than "Sjogren's Syndrome".

Diseases [C]
Musculoskeletal Diseases [C05]
Joint Diseases [C05.550]
Arthritis [C05.550.114]
Arthritis, Rheumatoid [C05.550.114.154]
Sjogren's Syndrome [C05.550.114.154.774]
Rheumatic Diseases [C05.799]
Arthritis, Rheumatoid [C05.799.114]
Sjogren's Syndrome [C05.799.114.774]
Stomatognathic Diseases [C07]
Mouth Diseases [C07.465]
Salivary Gland Diseases [C07.465.815]
Xerostomia [C07.465.815.929]
Sjogren's Syndrome [C07.465.815.929.669]
Eye Diseases [C11]
Lacrimal Apparatus Diseases [C11.496]
Dry Eye Syndromes [C11.496.260]
Sjogren's Syndrome [C11.496.260.719]
Skin and Connective Tissue Diseases [C17]
Connective Tissue Diseases [C17.300]
Rheumatic Diseases [C17.300.775]
Arthritis, Rheumatoid [C17.300.775.099]
Sjogren's Syndrome [C17.300.775.099.774]
Immune System Diseases [C20]
Autoimmune Diseases [C20.111]
Arthritis, Rheumatoid [C20.111.199]
Sjogren's Syndrome [C20.111.199.774]

Below are MeSH descriptors whose meaning is related to "Sjogren's Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Sjogren's Syndrome".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Sjogren's Syndrome" by people in this website by year, and whether "Sjogren's Syndrome" was a major or minor topic of these publications.

Bar chart showing 100 publications over 26 distinct years, with a maximum of 10 publications in 2016 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	0	1	1
1995	2	0	2
1997	1	0	1
1998	2	0	2
1999	0	2	2
2001	2	0	2
2002	2	1	3
2003	1	0	1
2004	2	0	2
2005	2	0	2
2006	1	1	2
2007	2	1	3
2008	3	0	3
2009	1	0	1
2010	1	2	3
2011	2	0	2
2012	2	0	2
2013	9	0	9
2014	5	0	5
2015	3	1	4
2016	9	1	10
2017	8	1	9
2018	7	1	8
2019	4	3	7
2020	10	0	10
2021	4	0	4

Below are the most recent publications written about "Sjogren's Syndrome" by people in Profiles.

Retamozo S, Acar-Denizli N, Horváth IF, Ng WF, Rasmussen A, Dong X, Li X, Baldini C, Olsson P, Priori R, Seror R, Gottenberg JE, Kruize AA, Hernandez-Molina G, Vissink A, Sandhya P, Armagan B, Quartuccio L, Sebastian A, Praprotnik S, Bartoloni E, Kwok SK, Kvarnstrom M, Rischmueller M, Soláns-Laqué R, Sene D, Pasoto SG, Suzuki Y, Isenberg DA, Valim V, Nordmark G, Nakamura H, Fernandes Moça Trevisani V, Hofauer B, Sisó-Almirall A, Giacomelli R, Devauchelle-Pensec V, Bombardieri M, Atzeni F, Hammenfors D, Maure B, Carsons SE, Gheita T, Sánchez-Berná I, López-Dupla M, Morel J, Inanç N, Fonseca-Aizpuru E, Morcillo C, Vollenweider C, Melchor S, Vázquez M, Díaz-Cuiza E, Consani-Fernández S, de-Miguel-Campo B, Szántó A, Bombardieri S, Gattamelata A, Hinrichs A, Sánchez-Guerrero J, Danda D, Kilic L, De Vita S, Wiland P, Gerli R, Park SH, Wahren-Herlenius M, Bootsma H, Mariette X, Ramos-Casals M, Brito-Zerón P. Influence of the age at diagnosis in the disease expression of primary Sjögren syndrome. Analysis of 12,753 patients from the Sjögren Big Data Consortium. Clin Exp Rheumatol. 2021 Nov-Dec; 39 Suppl 133(6):166-174.

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Norheim KB, Imgenberg-Kreuz J, Alexsson A, Johnsen SJA, Bårdsen K, Brun JG, Dehkordi RK, Theander E, Mandl T, Jonsson R, Ng WF, Lessard CJ, Rasmussen A, Sivilis K, Ronnblom L, Omdal R. Genetic variants at the RTP4/MASP1 locus are associated with fatigue in Scandinavian patients with primary Sjögren's syndrome. RMD Open. 2021 12; 7(3).

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Ramos-Casals M, Acar-Denizli N, Vissink A, Brito-Zerón P, Li X, Carubbi F, Priori R, Toplak N, Baldini C, Faugier-Fuentes E, Kruize AA, Mandl T, Tomiita M, Gandolfo S, Hashimoto K, Hernandez-Molina G, Hofauer B, Mendieta-Zerón S, Rasmussen A, Sandhya P, Sene D, Trevisani VFM, Isenberg D, Sundberg E, Pasoto SG, Sebastian A, Suzuki Y, Retamozo S, Xu B, Giacomelli R, Gattamelata A, Bizjak M, Bombardieri S, Loor-Chavez RE, Hinrichs A, Olsson P, Bootsma H, Lieberman SM. Childhood-onset of primary Sjögren's syndrome: phenotypic characterization at diagnosis of 158 children. Rheumatology (Oxford). 2021 10 02; 60(10):4558-4567.

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Berndt N, Bippes CC, Michalk I, Bartsch T, Arndt C, Puentes-Cala E, Soto JA, Loureiro LR, Kegler A, Bachmann D, Gross JK, Gross T, Kurien BT, Scofield RH, Farris AD, James JA, Bergmann R, Schmitz M, Feldmann A, Bachmann MP. And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling. Int J Mol Sci. 2021 Sep 08; 22(18).

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Witas R, Rasmussen A, Scofield RH, Radfar L, Stone DU, Grundahl K, Lewis D, Sivils KL, Lessard CJ, Farris AD, Nguyen CQ. Defective Efferocytosis in a Murine Model of Sjögren's Syndrome Is Mediated by Dysfunctional Mer Tyrosine Kinase Receptor. Int J Mol Sci. 2021 Sep 08; 22(18).

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Imgenberg-Kreuz J, Rasmussen A, Sivils K, Nordmark G. Genetics and epigenetics in primary Sjögren's syndrome. Rheumatology (Oxford). 2021 05 14; 60(5):2085-2098.

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Kabeerdoss J, Sandhya P, Kurien BT, Scofield RH, Danda D. In vitro effects of curcumin on proinflammatory cytokines and expression of their genes in minor salivary gland tissue of patients with Sjogren's syndrome. Rheumatol Int. 2022 03; 42(3):545-551.

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Berndt N, Bippes CC, Michalk I, Bachmann D, Bachmann J, Puentes-Cala E, Bartsch T, Loureiro LR, Kegler A, Bergmann R, Gross JK, Gross T, Kurien BT, Scofield RH, Farris AD, James JA, Schmitz M, Fahmy K, Feldmann A, Arndt C, Bachmann MP. Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is Able to Form Dimers and Oligomers in a Redox Dependent Manner. Int J Mol Sci. 2021 Mar 25; 22(7).

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Jog NR, James JA. Epstein Barr Virus and Autoimmune Responses in Systemic Lupus Erythematosus. Front Immunol. 2020; 11:623944.

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Oyelakin A, Horeth E, Song EC, Min S, Che M, Marzullo B, Lessard CJ, Rasmussen A, Radfar L, Scofield RH, Lewis DM, Stone DU, Grundahl K, De Rossi SS, Kurago Z, Farris AD, Sivils KL, Sinha S, Kramer JM, Romano RA. Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjögren's Syndrome. Front Immunol. 2020; 11:606268.

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