"Sjogren's Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
| Descriptor ID |
D012859
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| MeSH Number(s) |
C05.550.114.154.774 C05.799.114.774 C07.465.815.929.669 C11.496.260.719 C17.300.775.099.774 C20.111.199.774
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sjogren's Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Sjogren's Syndrome".
This graph shows the total number of publications written about "Sjogren's Syndrome" by people in this website by year, and whether "Sjogren's Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 2 | 1 | 3 |
| 2007 | 3 | 1 | 4 |
| 2008 | 3 | 0 | 3 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 2 | 4 |
| 2011 | 3 | 0 | 3 |
| 2012 | 2 | 0 | 2 |
| 2013 | 11 | 0 | 11 |
| 2014 | 5 | 0 | 5 |
| 2015 | 3 | 1 | 4 |
| 2016 | 11 | 1 | 12 |
| 2017 | 8 | 1 | 9 |
| 2018 | 7 | 1 | 8 |
| 2019 | 5 | 3 | 8 |
| 2020 | 11 | 0 | 11 |
| 2021 | 10 | 1 | 11 |
| 2022 | 3 | 0 | 3 |
| 2023 | 3 | 0 | 3 |
| 2024 | 2 | 1 | 3 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sjogren's Syndrome" by people in Profiles.
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Mitochondrial dysfunction and fatigue in Sj?gren's disease. RMD Open. 2025 Apr 23; 11(2).
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Dysregulated Ca2+ signaling, fluid secretion, and mitochondrial function in a mouse model of early Sj?gren's disease. Elife. 2024 Sep 11; 13.
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2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Rheumatol. 2024 Aug; 76(8):1201-1213.
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Deleting Mitochondrial Superoxide Dismutase 2 in Salivary Gland Ductal Epithelial Cells Recapitulates Non-Sj?gren's Sicca Syndrome. Int J Mol Sci. 2024 May 30; 25(11).
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The Potential Utility of Salivary and Tear Proteomics to Discriminate Sj?gren's Disease from Non-Sj?gren's Sicca. Int J Mol Sci. 2023 Dec 15; 24(24).
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Pervasive Sharing of Causal Genetic Risk Factors Contributes to Clinical and Molecular Overlap between Sj?gren's Disease and Systemic Lupus Erythematosus. Int J Mol Sci. 2023 Sep 22; 24(19).
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Anti-vimentin antibodies are associated with higher severity of Sj?gren's disease. Clin Immunol. 2023 02; 247:109243.
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Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells. Nat Commun. 2022 07 27; 13(1):4287.
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Antibody deposition on vascular endothelial cells contributes to localized inflammation in salivary glands. J Oral Pathol Med. 2022 Aug; 51(7):674-677.
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X-linked genes exhibit miR6891-5p-regulated skewing in Sjögren's syndrome. J Mol Med (Berl). 2022 Sep; 100(9):1253-1265.