14-alpha Demethylase Inhibitors
"14-alpha Demethylase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.
| Descriptor ID |
D058888
|
| MeSH Number(s) |
D27.505.389.500.059 D27.505.519.389.335.059 D27.505.519.389.870.100 D27.505.696.399.450.855.100
|
| Concept/Terms |
14-alpha Demethylase Inhibitors- 14-alpha Demethylase Inhibitors
- 14 alpha Demethylase Inhibitors
- Inhibitors, 14-alpha Demethylase
- CYP51 Inhibitors
- Inhibitors, CYP51
- Lanosterol 14 alpha-Demethylase Inhibitors
- Lanosterol 14 alpha Demethylase Inhibitors
- 14alpha-Demethylase Inhibitors
- 14alpha Demethylase Inhibitors
- Inhibitors, 14alpha-Demethylase
|
Below are MeSH descriptors whose meaning is more general than "14-alpha Demethylase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "14-alpha Demethylase Inhibitors".
This graph shows the total number of publications written about "14-alpha Demethylase Inhibitors" by people in this website by year, and whether "14-alpha Demethylase Inhibitors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "14-alpha Demethylase Inhibitors" by people in Profiles.
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Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast. ACS Chem Biol. 2017 02 17; 12(2):422-434.
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Targeting Ergosterol biosynthesis in Leishmania donovani: essentiality of sterol 14 alpha-demethylase. PLoS Negl Trop Dis. 2015 Mar; 9(3):e0003588.