"Small Molecule Libraries" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Large collections of small molecules (molecular weight about 600 or less), of similar or diverse nature which are used for high-throughput screening analysis of the gene function, protein interaction, cellular processing, biochemical pathways, or other chemical interactions.
| Descriptor ID |
D054852
|
| MeSH Number(s) |
D27.720.470.765
|
| Concept/Terms |
Small Molecule Libraries- Small Molecule Libraries
- Libraries, Small Molecule
- Molecule Libraries, Small
- Molecular Libraries, Small
- Libraries, Small Molecular
- Small Molecular Libraries
- Chemical Libraries
- Libraries, Chemical
|
Below are MeSH descriptors whose meaning is more general than "Small Molecule Libraries".
Below are MeSH descriptors whose meaning is more specific than "Small Molecule Libraries".
This graph shows the total number of publications written about "Small Molecule Libraries" by people in this website by year, and whether "Small Molecule Libraries" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 2 | 1 | 3 |
| 2017 | 2 | 0 | 2 |
| 2018 | 4 | 1 | 5 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Small Molecule Libraries" by people in Profiles.
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Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening. SLAS Discov. 2021 01; 26(1):113-121.
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Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells. RNA Biol. 2018; 15(11):1420-1432.
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Small Molecule Condensin Inhibitors. ACS Infect Dis. 2018 12 14; 4(12):1737-1745.
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An update on small molecule strategies targeting leishmaniasis. Eur J Med Chem. 2018 Sep 05; 157:339-367.
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Differentiating Antiproliferative and Chemopreventive Modes of Activity for Electron-Deficient Aryl Isothiocyanates against Human MCF-7 Cells. ChemMedChem. 2018 08 20; 13(16):1695-1710.
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Counting on Fragment Based Drug Design Approach for Drug Discovery. Curr Top Med Chem. 2018; 18(27):2284-2293.
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Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators. PLoS One. 2017; 12(6):e0178678.
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Novel EGFR (T790M)-cMET dual inhibitors: putative therapeutic agents for non-small-cell lung cancer. Future Med Chem. 2017 04; 9(5):469-483.
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Identification of small molecules that protect pancreatic ß cells against endoplasmic reticulum stress-induced cell death. ACS Chem Biol. 2014 Dec 19; 9(12):2796-806.
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Selective inhibition of rDNA transcription by a small-molecule peptide that targets the interface between RNA polymerase I and Rrn3. Mol Cancer Res. 2014 Nov; 12(11):1586-96.