Christina Bourne to Models, Molecular
This is a "connection" page, showing publications Christina Bourne has written about Models, Molecular.
Connection Strength
0.592
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The structure and competitive substrate inhibition of dihydrofolate reductase from Enterococcus faecalis reveal restrictions to cofactor docking. Biochemistry. 2014 Feb 25; 53(7):1228-38.
Score: 0.103
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Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Antimicrob Agents Chemother. 2009 Jul; 53(7):3065-73.
Score: 0.073
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A mutant hepatitis B virus core protein mimics inhibitors of icosahedral capsid self-assembly. Biochemistry. 2009 Mar 03; 48(8):1736-42.
Score: 0.073
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Small-molecule effectors of hepatitis B virus capsid assembly give insight into virus life cycle. J Virol. 2008 Oct; 82(20):10262-70.
Score: 0.070
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Global structural changes in hepatitis B virus capsids induced by the assembly effector HAP1. J Virol. 2006 Nov; 80(22):11055-61.
Score: 0.061
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Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus. ACS Chem Biol. 2022 01 21; 17(1):85-102.
Score: 0.044
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Evaluation of New Dihydrophthalazine-Appended 2,4-Diaminopyrimidines against Bacillus anthracis: Improved Syntheses Using a New Pincer Complex. Molecules. 2015 Apr 21; 20(4):7222-44.
Score: 0.028
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Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis. Bioorg Med Chem. 2015 Jan 01; 23(1):203-11.
Score: 0.027
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Synthesis and biological evaluation of 2,4-diaminopyrimidine-based antifolate drugs against Bacillus anthracis. Molecules. 2014 Mar 17; 19(3):3231-46.
Score: 0.026
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Inhibition of bacterial dihydrofolate reductase by 6-alkyl-2,4-diaminopyrimidines. ChemMedChem. 2012 Nov; 7(11):1974-82.
Score: 0.023
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Synthesis and biological activity of substituted 2,4-diaminopyrimidines that inhibit Bacillus anthracis. Eur J Med Chem. 2012 Aug; 54:387-96.
Score: 0.023
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Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody. Biochem J. 2006 May 01; 395(3):473-81.
Score: 0.015
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A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly. Proc Natl Acad Sci U S A. 2005 Jun 07; 102(23):8138-43.
Score: 0.014
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Comparison of the three-dimensional structures of a human Bence-Jones dimer crystallized on Earth and aboard US Space Shuttle Mission STS-95. J Mol Recognit. 2003 Mar-Apr; 16(2):83-90.
Score: 0.012