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Robert Hal Scofield

TitleMember
InstitutionOklahoma Medical Research Foundation
DepartmentArthritis and Clinical Immunology
Addressn/a
825 N.E. 13th Street
Oklahoma City OK 73104
Phone405/271-7144
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    Collapse Research 
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    R21DE029303     (SCOFIELD, ROBERT HAL)May 1, 2020 - Apr 30, 2022
    NIH
    ENBA2 in the pathogenesis of Sjogren's Syndrome
    Role: Principal Investigator
    I01CX001877     (SCOFIELD, ROBERT HAL)Apr 1, 2020 - Mar 31, 2024
    NIH
    Autoimmunity in Post-Traumatic Stress Disorder
    Role: Principal Investigator
    IS1BX005038     (SCOFIELD, ROBERT HAL)Sep 1, 2019 - Sep 30, 2020
    NIH
    ShEEP Request for Peggy Sue by Bio-Techne
    Role: Principal Investigator
    R21DE026877     (SCOFIELD, ROBERT HAL)Aug 1, 2017 - Jul 31, 2019
    NIH
    Mitochondrial dysfunction, metabolic syndrome and oxidative damage in Sjogren's Syndrome
    Role: Principal Investigator
    I01BX001451     (SCOFIELD, ROBERT HAL)Apr 1, 2012 - Sep 30, 2025
    NIH
    Sex Chromosome Aneuploidies in Autoimmune Disease
    Role: Principal Investigator
    R01DE017561     (SCOFIELD, R HAL)Aug 1, 2006 - May 31, 2011
    NIH
    Sjogren's model with anti-Ro/La and Salivary Pathology and Dysfunction
    Role: Principal Investigator
    R01AR053734     (SCOFIELD, R HAL)Apr 12, 2006 - Jan 31, 2012
    NIH
    The X Chromosome in Systemic Lupus Erythematosus
    Role: Principal Investigator
    K24AR049743     (SCOFIELD, R HAL)Jul 1, 2003 - Dec 30, 2008
    NIH
    Genetics of Severe Systemic Lupus Erythematosus (SLE) defined by thrombocytopenia
    Role: Principal Investigator
    R55AR047341     (SCOFIELD, R HAL)Sep 30, 2001 - Feb 28, 2004
    NIH
    A MODEL OF SJOGREN'S SYNDROME WITH ANTI-RO/LA ANTIBODIES
    Role: Principal Investigator
    F06TW002260     (SCOFIELD, R HAL)Sep 18, 1998
    NIH
    B27 RESTRICTED T CELL RESPONSE TO B27 MIMIC PEPTIDES
    Role: Principal Investigator
    R29AR042532     (SCOFIELD, R HAL)Apr 1, 1996 - Mar 31, 2002
    NIH
    B27 BINDING BACTERIAL AND SELF PEPTIDES IN B27 ARTHRITIS
    Role: Principal Investigator
    K11AR001844     (SCOFIELD, R HAL)Mar 15, 1992 - Feb 28, 1998
    NIH
    ORIGIN OF ANTIRO/SSA ANTIBODY
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Longobardi S, Lopez-Davis C, Khatri B, Georgescu C, Pritchett-Frazee C, Lawrence C, Rasmussen A, Radfar L, Scofield RH, Baer AN, Robinson SA, Darrah E, Axtell RC, Pardo G, Wren JD, Koelsch KA, Guthridge JM, James JA, Lessard CJ, Farris AD. Autoantibodies identify primary Sj?gren's syndrome in patients lacking serum IgG specific for Ro/SS-A and La/SS-B. Ann Rheum Dis. 2023 May 05. PMID: 37147113.
      Citations:    
    2. Bagavant H, Araszkiewicz AM, Rasmussen A, Pezant N, Montgomery C, Scofield RH, Farris D, Lessard CJ, Deshmukh US. Anti-vimentin antibodies are associated with higher severity of Sj?gren's disease. Clin Immunol. 2023 02; 247:109243. PMID: 36702181; PMCID: PMC10037908.
      Citations:    Fields:    Translation:Humans
    3. Joachims ML, Khatri B, Li C, Tessneer KL, Ice JA, Stolarczyk AM, Means N, Grundahl KM, Glenn SB, Kelly JA, Lewis DM, Radfar L, Stone DU, Guthridge JM, James JA, Scofield RH, Wiley GB, Wren JD, Gaffney PM, Montgomery CG, Sivils KL, Rasmussen A, Farris AD, Adrianto I, Lessard CJ. Dysregulated long non-coding RNA in Sjögren's disease impacts both interferon and adaptive immune responses. RMD Open. 2022 Nov; 8(2). PMID: 36456101.
      Citations:    Translation:Humans
    4. Khatri B, Tessneer KL, Rasmussen A, Aghakhanian F, Reksten TR, Adler A, Alevizos I, Anaya JM, Aqrawi LA, Baecklund E, Brun JG, Bucher SM, Eloranta ML, Engelke F, Forsblad-d'Elia H, Glenn SB, Hammenfors D, Imgenberg-Kreuz J, Jensen JL, Johnsen SJA, Jonsson MV, Kvarnström M, Kelly JA, Li H, Mandl T, Martín J, Nocturne G, Norheim KB, Palm Ø, Skarstein K, Stolarczyk AM, Taylor KE, Teruel M, Theander E, Venuturupalli S, Wallace DJ, Grundahl KM, Hefner KS, Radfar L, Lewis DM, Stone DU, Kaufman CE, Brennan MT, Guthridge JM, James JA, Scofield RH, Gaffney PM, Criswell LA, Jonsson R, Eriksson P, Bowman SJ, Omdal R, Rönnblom L, Warner B, Rischmueller M, Witte T, Farris AD, Mariette X, Alarcon-Riquelme ME, PRECISESADS Clinical Consortium, Shiboski CH, Sjögren’s International Collaborative Clinical Alliance (SICCA), Wahren-Herlenius M, Ng WF, UK Primary Sjögren’s Syndrome Registry, Sivils KL, Adrianto I, Nordmark G, Lessard CJ. Author Correction: Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells. Nat Commun. 2022 Oct 31; 13(1):6519. PMID: 36316359; PMCID: PMC9622850.
      Citations:    Fields:    
    5. Harley ITW, Allison K, Scofield RH. Polygenic autoimmune disease risk alleles impacting B cell tolerance act in concert across shared molecular networks in mouse and in humans. Front Immunol. 2022; 13:953439. PMID: 36090990; PMCID: PMC9450536.
      Citations:    Fields:    Translation:HumansAnimalsCells
    6. Xu L, Zhao J, Sun Q, Xu X, Wang L, Liu T, Wu Y, Zhu J, Geng L, Deng Y, Awgulewitsch A, Kamen DL, Oates JC, Raj P, Wakeland EK, Scofield RH, Guthridge JM, James JA, Hahn BH, McCurdy DK, Wang F, Zhang M, Tan W, Gilkeson GS, Tsao BP. Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus. Ann Rheum Dis. 2022 Dec; 81(12):1712-1721. PMID: 35977808.
      Citations:    Fields:    Translation:HumansAnimals
    7. Khatri B, Tessneer KL, Rasmussen A, Aghakhanian F, Reksten TR, Adler A, Alevizos I, Anaya JM, Aqrawi LA, Baecklund E, Brun JG, Bucher SM, Eloranta ML, Engelke F, Forsblad-d'Elia H, Glenn SB, Hammenfors D, Imgenberg-Kreuz J, Jensen JL, Johnsen SJA, Jonsson MV, Kvarnström M, Kelly JA, Li H, Mandl T, Martín J, Nocturne G, Norheim KB, Palm Ø, Skarstein K, Stolarczyk AM, Taylor KE, Teruel M, Theander E, Venuturupalli S, Wallace DJ, Grundahl KM, Hefner KS, Radfar L, Lewis DM, Stone DU, Kaufman CE, Brennan MT, Guthridge JM, James JA, Scofield RH, Gaffney PM, Criswell LA, Jonsson R, Eriksson P, Bowman SJ, Omdal R, Rönnblom L, Warner B, Rischmueller M, Witte T, Farris AD, Mariette X, Alarcon-Riquelme ME, Shiboski CH, Wahren-Herlenius M, Ng WF, Sivils KL, Adrianto I, Nordmark G, Lessard CJ. Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells. Nat Commun. 2022 07 27; 13(1):4287. PMID: 35896530.
      Citations: 2     Fields:    Translation:Humans
    8. Kabeerdoss J, Danda D, Goel R, Mohan H, Danda S, Scofield RH. Genome-Wide DNA Methylation Profiling in CD8 T-Cells and Gamma Delta T-Cells of Asian Indian Patients With Takayasu Arteritis. Front Cell Dev Biol. 2022; 10:843413. PMID: 35813204; PMCID: PMC9259853.
      Citations:    
    9. Shaw TM, Zhang W, McCoy SS, Pagenkopf A, Carp DM, Garg S, Parker MH, Qiu X, Scofield RH, Galipeau J, Liang Y. X-linked genes exhibit miR6891-5p-regulated skewing in Sjögren's syndrome. J Mol Med (Berl). 2022 Sep; 100(9):1253-1265. PMID: 35538149; PMCID: PMC9420820.
      Citations: 2     Fields:    Translation:Humans
    10. Scofield RH, Lewis VM, Cavitt J, Kurien BT, Assassi S, Martin J, Gorlova O, Gregersen P, Lee A, Rider LG, O'Hanlon T, Rothwell S, Lilleker J, Kochi Y, Terao C, Igoe A, Stevens W, Sahhar J, Roddy J, Rischmueller M, Lester S, Proudman S, Chen S, Brown MA, Mayes MD, Lamb JA, Miller FW. 47XXY and 47XXX in Scleroderma and Myositis. ACR Open Rheumatol. 2022 Jun; 4(6):528-533. PMID: 35352506.
      Citations: 3     
    11. Kabeerdoss J, Sandhya P, Kurien BT, Scofield RH, Danda D. Correction to: In vitro effects of curcumin on proinflammatory cytokines and expression of their genes in minor salivary gland tissue of patients with Sjogren's syndrome. Rheumatol Int. 2022 Mar; 42(3):553. PMID: 33963892.
      Citations:    Fields:    
    12. Kumari S, Bubak M, Schoenberg HM, Davidyan A, Elliehausen CJ, Kuhn KG, VanWagoner TM, Karaman R, Scofield RH, Miller BF, Konopka AR. Antecedent Metabolic Health and Metformin (ANTHEM) Aging study: Rationale and study design for a randomized controlled trial. J Gerontol A Biol Sci Med Sci. 2021 Dec 02. PMID: 34865016.
      Citations:    Fields:    
    13. Witas R, Rasmussen A, Scofield RH, Radfar L, Stone DU, Grundahl K, Lewis D, Sivils KL, Lessard CJ, Farris AD, Nguyen CQ. Defective Efferocytosis in a Murine Model of Sjögren's Syndrome Is Mediated by Dysfunctional Mer Tyrosine Kinase Receptor. Int J Mol Sci. 2021 Sep 08; 22(18). PMID: 34575873.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    14. Kabeerdoss J, Sandhya P, Kurien BT, Scofield RH, Danda D. In vitro effects of curcumin on proinflammatory cytokines and expression of their genes in minor salivary gland tissue of patients with Sjogren's syndrome. Rheumatol Int. 2022 03; 42(3):545-551. PMID: 33861386.
      Citations: 1     Fields:    Translation:HumansAnimals
    15. Harris VM, Harley ITW, Kurien BT, Koelsch KA, Scofield RH. Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing CXorf21. Front Immunol. 2019; 10:578. PMID: 31001245.
      Citations: 16     Fields:    Translation:HumansCells
    16. LaBryer L, Sharma R, Chaudhari KS, Talsania M, Scofield RH. Kratom, an Emerging Drug of Abuse, Raises Prolactin and Causes Secondary Hypogonadism: Case Report. J Investig Med High Impact Case Rep. 2018 Jan-Dec; 6:2324709618765022. PMID: 29568783; PMCID: PMC5858613.
      Citations: 6     Fields:    
    17. Talsania M, Scofield RH. Menopause and Rheumatic Disease. Rheum Dis Clin North Am. 2017 05; 43(2):287-302. PMID: 28390570; PMCID: PMC5385852.
      Citations: 14     Fields:    Translation:Humans
    18. Danda D, Sharma R, Truong D, Koelsch KA, Kurien BT, Bagavant H, Deshmukh U, Kaufman CE, Lewis DM, Stone DU, Radfar L, Rasmussen A, Sivils KL, Scofield RH. Anti-La positive, anti-Ro negative subset of primary Sjögren's syndrome: anti-La is a reality but is the disease? Clin Exp Rheumatol. 2017 May-Jun; 35(3):438-444. PMID: 28229827.
      Citations: 5     Fields:    Translation:Humans
    19. Sandhya P, Kurien BT, Danda D, Scofield RH. Update on Pathogenesis of Sjogren's Syndrome. Curr Rheumatol Rev. 2017; 13(1):5-22. PMID: 27412602.
      Citations: 42     Fields:    Translation:Humans
    20. Kurien BT, Fesmire J, Anderson CJ, Scofield RH. Anti-Ro and Concomitant Anti-La Autoantibodies Strongly Associated With Anti-oxLDL or Anti-Phospholipid Antibody in Systemic Lupus Erythematosus. J Clin Rheumatol. 2016 Dec; 22(8):418-425. PMID: 27870764.
      Citations: 2     Fields:    Translation:Humans
    21. Wolska N, Rybakowska P, Rasmussen A, Brown M, Montgomery C, Klopocki A, Grundahl K, Scofield RH, Radfar L, Stone DU, Anaya JM, Ice JA, Lessard CJ, Lewis DM, Rhodus NL, Gopalakrishnan R, Huang AJ, Hughes PJ, Rohrer MD, Weisman MH, Venuturupalli S, Guthridge JM, James JA, Sivils KL, Bagavant H, Deshmukh US. Brief Report: Patients With Primary Sjögren's Syndrome Who Are Positive for Autoantibodies to Tripartite Motif-Containing Protein 38 Show Greater Disease Severity. Arthritis Rheumatol. 2016 Mar; 68(3):724-9. PMID: 26636433.
      Citations: 8     Fields:    Translation:Humans
    22. Kurien BT, Danda D, Scofield RH. Therapeutic potential of curcumin and curcumin analogues in rheumatology. Int J Rheum Dis. 2015 Jul; 18(6):591-3. PMID: 26301972.
      Citations: 1     Fields:    Translation:AnimalsCells
    23. Sandhya P, Jeyaseelan L, Scofield RH, Danda D. Clinical Characteristics and Outcome of Primary Sjogren's Syndrome: A Large Asian Indian Cohort. Open Rheumatol J. 2015; 9:36-45. PMID: 26161156; PMCID: PMC4493630.
      Citations: 12     
    24. Lu X, Zoller EE, Weirauch MT, Wu Z, Namjou B, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell LA, Vilá LM, Alarcón-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Joo YB, Choi J, Bae SC, Boackle SA, Graham DC, Vyse TJ, Guthridge JM, Gaffney PM, Langefeld CD, Kelly JA, Greis KD, Kaufman KM, Harley JB, Kottyan LC. Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. Am J Hum Genet. 2015 May 07; 96(5):731-9. PMID: 25865496.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    25. Clark EG, Knoll G, Bugeja A, Burns KD, Scofield RH. Lupus after kidney donation to an affected male relative. Transplantation. 2015 Apr; 99(4):e27-8. PMID: 25827324; PMCID: PMC5664938.
      Citations: 1     Fields:    Translation:Humans
    26. Fayyaz A, Igoe A, Kurien BT, Danda D, James JA, Stafford HA, Scofield RH. Haematological manifestations of lupus. Lupus Sci Med. 2015; 2(1):e000078. PMID: 25861458.
      Citations: 63     Fields:    
    27. Szczerba BM, Kaplonek P, Wolska N, Podsiadlowska A, Rybakowska PD, Dey P, Rasmussen A, Grundahl K, Hefner KS, Stone DU, Young S, Lewis DM, Radfar L, Scofield RH, Sivils KL, Bagavant H, Deshmukh US. Interaction between innate immunity and Ro52-induced antibody causes Sjögren's syndrome-like disorder in mice. Ann Rheum Dis. 2016 Mar; 75(3):617-22. PMID: 25906316.
      Citations: 30     Fields:    Translation:HumansAnimals
    28. Vaughn SE, Foley C, Lu X, Patel ZH, Zoller EE, Magnusen AF, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath S, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Reveille JD, Anaya JM, James JA, Moser KL, Criswell LA, Vilá LM, Alarcón-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Binjoo Y, Choi J, Bae SC, Boackle SA, Vyse TJ, Guthridge JM, Namjou B, Gaffney PM, Langefeld CD, Kaufman KM, Kelly JA, Harley IT, Harley JB, Kottyan LC. Lupus risk variants in the PXK locus alter B-cell receptor internalization. Front Genet. 2014; 5:450. PMID: 25620976.
      Citations: 17     
    29. Namjou B, Kim-Howard X, Sun C, Adler A, Chung SA, Kaufman KM, Kelly JA, Glenn SB, Guthridge JM, Scofield RH, Kimberly RP, Brown EE, Alarcón GS, Edberg JC, Kim JH, Choi J, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Boackle SA, Freedman BI, Tsao BP, Langefeld CD, Vyse TJ, Jacob CO, Pons-Estel B, Niewold TB, Moser Sivils KL, Merrill JT, Anaya JM, Gilkeson GS, Gaffney PM, Bae SC, Alarcón-Riquelme ME, Harley JB, Criswell LA, James JA, Nath SK. PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes. PLoS One. 2013; 8(8):e69404. PMID: 23950893.
      Citations: 24     Fields:    Translation:Humans
    30. Scofield AK, Radfar L, Ice JA, Vista E, Anaya JM, Houston G, Lewis D, Stone DU, Chodosh J, Hefner K, Lessard CJ, Moser KL, Scofield RH. Relation of sensory peripheral neuropathy in Sjögren syndrome to anti-Ro/SSA. J Clin Rheumatol. 2012 Sep; 18(6):290-3. PMID: 22955477.
      Citations: 12     Fields:    Translation:Humans
    31. Lee YJ, Scofield RH, Hyon JY, Yun PY, Lee HJ, Lee EY, Lee EB, Song YW. Salivary chemokine levels in patients with primary Sjogren's syndrome. Rheumatology (Oxford). 2010 Sep; 49(9):1747-52. PMID: 20525739; PMCID: PMC2919196.
      Citations: 19     Fields:    Translation:Humans
    32. Shenoi J, Kurien BT, Kurono S, Mascarenhas R, Matsumoto H, Scofield RH. Cost-benefit analysis of a method using diatomaceous earth to purify Tamm-Horsfall protein. Biotechniques. 2004 Jan; 36(1):64-6. PMID: 14740486.
      Citations:    Fields:    
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