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Darren J Lee

InstitutionUniversity of Oklahoma Health Sciences Center
AddressDMEI 419
608 Stanton L Young Blvd
Oklahoma City OK 73104
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    R01EY024951     (LEE, DARREN JAMES)Aug 1, 2015 - Mar 31, 2025
    Immunobiology of EAU Recovery Through the Melanocortin-Adenosinergic Pathway
    Role: Principal Investigator

    R21EY029240     (LEE, DARREN JAMES)May 1, 2019 - Apr 30, 2021
    Dynamics of the Ocular Immune Response During Uveitis
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. McDonald T, Muhammad F, Peters K, Lee DJ. Combined Deficiency of the Melanocortin 5 Receptor and Adenosine 2A Receptor Unexpectedly Provides Resistance to Autoimmune Disease in a CD8+ T Cell-Dependent Manner. Front Immunol. 2021; 12:742154. PMID: 34867964.
      Citations:    Fields:    Translation:AnimalsCells
    2. Lee DJ, Xu H, Taylor AW. Editorial: Retinal Immunobiology and Retinopathy. Front Immunol. 2021; 12:758375. PMID: 34539681.
      Citations:    Fields:    Translation:HumansCells
    3. Muhammad F, Avalos PN, Mursalin MH, Ma JX, Callegan MC, Lee DJ. Kallistatin Attenuates Experimental Autoimmune Uveitis by Inhibiting Activation of T Cells. Front Immunol. 2020; 11:975. PMID: 32508841.
      Citations: 2     Fields:    Translation:AnimalsCells
    4. Muhammad F, Wang D, McDonald T, Walsh M, Drenen K, Montieth A, Foster CS, Lee DJ. TIGIT+ A2Ar-Dependent anti-uveitic Treg cells are a novel subset of Tregs associated with resolution of autoimmune uveitis. J Autoimmun. 2020 07; 111:102441. PMID: 32201225.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    5. Lee DJ. The relationship between TIGIT+ regulatory T cells and autoimmune disease. Int Immunopharmacol. 2020 Jun; 83:106378. PMID: 32172208.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    6. Muhammad F, Wang D, Montieth A, Lee S, Preble J, Foster CS, Larson TA, Ding K, Dvorak JD, Lee DJ. PD-1+ melanocortin receptor dependent-Treg cells prevent autoimmune disease. Sci Rep. 2019 11 15; 9(1):16941. PMID: 31729418.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    7. Muhammad FY, Peters K, Wang D, Lee DJ. Exacerbation of autoimmune uveitis by obesity occurs through the melanocortin 5 receptor. J Leukoc Biol. 2019 10; 106(4):879-887. PMID: 31287586.
      Citations: 6     Fields:    Translation:AnimalsCells
    8. Muhammad F, Trivett A, Wang D, Lee DJ. Tissue-specific production of MicroRNA-155 inhibits melanocortin 5 receptor-dependent suppressor macrophages to promote experimental autoimmune uveitis. Eur J Immunol. 2019 11; 49(11):2074-2082. PMID: 31177529.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    9. Lee DJ, Preble J, Lee S, Foster CS, Taylor AW. MC5r and A2Ar Deficiencies During Experimental Autoimmune Uveitis Identifies Distinct T cell Polarization Programs and a Biphasic Regulatory Response. Sci Rep. 2016 11 25; 6:37790. PMID: 27886238.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    10. Lee DJ. Intraocular Implants for the Treatment of Autoimmune Uveitis. J Funct Biomater. 2015 Jul 31; 6(3):650-66. PMID: 26264035.
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