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Tracy Kent Teague

TitleProf
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentIntegrative Immunology Center
AddressSAC 3E34
4502 E 41st St
Tulsa OK 74135
Phone918/660-3921
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    Collapse Biography 
    Collapse education and training
    University of Texas Health Science Center and MD Anderson Cancer Center, Houston, TXPhD06/1995 Immunology
    Howard Hughes Medical Institute, National Jewish Health, Denver, COPostdoc12/1999 Immunology

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    1P20RR015577-01     (CAPRA, J DONALD)Sep 30, 2000 - Aug 31, 2005
    NIH
    MENTORING IMMUNOLOGY IN OKLAHOMA--A BIOMEDICAL PROGRAM
    Role: Subproject PI

    HR03-124     (TEAGUE, T KENT)Jul 1, 2003 - Jun 30, 2006
    OCAST
    Differential IL-7 Signaling in T Cell Development
    Role: Principal Investigator

    ACS- IRG-05-066-01     (TEAGUE, T KENT)Mar 1, 2006 - Feb 28, 2007
    American Cancer Society: ACS Institutional Research Seed Grant
    Laser and TLR-Agonist Immunotherapy: A Novel Autologous Melanoma Vaccine Strategy
    Role: Principal Investigator (Marie Hanigan was the parent grant PI)

    PHF1531     (VAN DE WIELE, C JUSTIN)Jul 1, 2006 - Jun 30, 2007
    Presbyterian Health Foundation (seed grant)
    Characterization of a novel transgenic CD28 promoter vector
    Role: Co-investigator

    HR07-095     (TEAGUE, T KENT)Aug 1, 2007 - Jul 31, 2010
    OCAST
    MCL-1 Effects on T Cell Development and Homeostasis
    Role: Principal Investigator

    HR09-166     (VAN DE WIELE, C JUSTIN)Aug 1, 2009 - Jun 30, 2012
    OCAST
    In vitro development of T cells on engineered stroma
    Role: Co-Investigator

    SMRI 10TAF-1401     (SAVITZ, JONATHAN)Oct 1, 2011 - Sep 30, 2014
    Stanley Medical Research Foundation
    Minocycline in the treatment of bipolar depression
    Role: Co-Investigator

    R01MH098099     (BODURKA, JERZY ALEKSANDER)Sep 1, 2012 - Jul 31, 2017
    NIH
    Inflammatory Transcripts, Genes and Positive Valence System Function in Anhedonia
    Role: Co-Investigator

    P20GM109097     (HAYS-GRUDO, JENNIFER)Jul 1, 2016 - Mar 31, 2021
    NIH
    CIRCA, the Center for Integrative Research on Childhood Adversity
    Role Description: Our primary question was whether or not thymocyte death due to failure of positive selection is regulated by loss of IL-7 signaling following TCR beta selection
    Role: Biomarker Core Director

    HR16-003     (MILLER, KENNETH)Aug 1, 2016 - Jul 31, 2019
    OCAST
    The role of glutamatergic sensory neurons in the initiation of and response to colitis
    Role: Co-Investigator

    R21NS099789     (MEIER, TIMOTHY B.)Jul 1, 2017 - Jun 30, 2020
    NIH
    Inflammation and Kynurenine Metabolites in the Acute Sequelae of Concussion
    Role: Co-Investigator

    P20GM121312     (PAULUS, MARTIN P.)Sep 15, 2017 - Jun 30, 2022
    NIH
    The Center for Neuroscience-based Mental Health Assessment and Prediction (NEUROMAP)
    Role: Research Core Co-Director

    NARSAD     (SAVITZ, JONATHAN)Jan 1, 2018 - Dec 31, 2018
    Brain and Behavior Research Foundation
    Impaired Adaptive Immunity in Depression: Relationship with Herpes Viruses and Inflammation
    Role: Co-Investigator

    R21MH113871     (SAVITZ, JONATHAN)Aug 1, 2018 - Jul 31, 2021
    NIH
    Acute modulation of neural circuitry regulating immune function in depression
    Role: Co-Investigator

    T99HP33558     (CRAWFORD, STEVE)Sep 1, 2019 - Aug 31, 2023
    HRSA
    Value Based Medical Student Education Training Program (TRU-OK)
    Role: Co-Investigator

    R34DA050343     (CROFF, JULIE MAY)Sep 30, 2019 - Mar 31, 2021
    NIH
    3/6 Planning for the HEALthy Early Development Study
    Role: Consultant

    R01DK127464     (WETHERILL, MARIANNA)Sep 17, 2020 - Aug 31, 2025
    NIH
    Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma (NOURISH OK)
    Role: Co-Investigator

    R01MH123652     (SAVITZ, JONATHAN)May 14, 2021 - Apr 30, 2026
    NIH
    Neural response to inflammatory challenge in major depressive disorder
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Burrows K, Figueroa-Hall LK, Kuplicki R, Stewart JL, Alarbi AM, Ramesh R, Savitz JB, Teague TK, Risbrough VB, Paulus MP. Neuronally-enriched exosomal microRNA-27b mediates acute effects of ibuprofen on reward-related brain activity in healthy adults: a randomized, placebo-controlled, double-blind trial. Sci Rep. 2022 01 17; 12(1):861. PMID: 35039595.
      Citations:    Fields:    Translation:Humans
    2. Thomas M, Savitz J, Zhang Y, Burrows K, Smith R, Figueroa-Hall L, Kuplicki R, Khalsa SS, Taki Y, Teague TK, Irwin MR, Yeh FC, Paulus MP, Zheng H. Elevated Systemic Inflammation Is Associated with Reduced Corticolimbic White Matter Integrity in Depression. Life (Basel). 2021 Dec 28; 12(1). PMID: 35054436.
      Citations:    
    3. Meier TB, Guedes VA, Smith EG, Sass D, Mithani S, Vorn R, Savitz J, Teague TK, McCrea MA, Gill JM. Extracellular vesicle-associated cytokines in sport-related concussion. Brain Behav Immun. 2022 02; 100:83-87. PMID: 34848337.
      Citations:    Fields:    
    4. Kuplicki R, Touthang J, Al Zoubi O, Mayeli A, Misaki M, Aupperle RL, Teague TK, McKinney BA, Paulus MP, Bodurka J. Common Data Elements, Scalable Data Management Infrastructure, and Analytics Workflows for Large-Scale Neuroimaging Studies. Front Psychiatry. 2021; 12:682495. PMID: 34220587.
      Citations:    
    5. Cosgrove KT, Kuplicki R, Savitz J, Burrows K, Simmons WK, Khalsa SS, Teague TK, Aupperle RL, Paulus MP. Impact of ibuprofen and peroxisome proliferator-activated receptor gamma on emotion-related neural activation: A randomized, placebo-controlled trial. Brain Behav Immun. 2021 08; 96:135-142. PMID: 34052365.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    6. Blair AL, Chiaf AL, Crockett EK, Teague TK, Croff JM. Validation of hair ethyl glucuronide using transdermal monitoring and self-reported alcohol use in women of childbearing potential. Neuropsychopharmacol Rep. 2021 06; 41(2):144-151. PMID: 33650766.
      Citations: 1     Fields:    Translation:Humans
    7. Shreffler KM, Joachims CN, Tiemeyer S, Simmons WK, Teague TK, Hays-Grudo J. Childhood Adversity and Perceived Distress from the COVID-19 Pandemic. Advers Resil Sci. 2021 Jan 28; 1-4. PMID: 33527096.
      Citations:    
    8. Zheng H, Bergamino M, Ford BN, Kuplicki R, Yeh FC, Bodurka J, Burrows K, Hunt PW, Teague TK, Irwin MR, Yolken RH, Paulus MP, Savitz J. Replicable association between human cytomegalovirus infection and reduced white matter fractional anisotropy in major depressive disorder. Neuropsychopharmacology. 2021 04; 46(5):928-938. PMID: 33500556.
      Citations: 3     Fields:    Translation:Humans
    9. Savitz J, Ford BN, Yeh HW, Akeman E, Cosgrove K, Clausen AN, Martell C, Kirlic N, Santiago J, Teague TK, Irwin MR, Paulus MP, Aupperle RL. Behavioral activation therapy for depression is associated with a reduction in the concentration of circulating quinolinic acid. Psychol Med. 2020 Nov 25; 1-10. PMID: 33234171.
      Citations: 1     Fields:    
    10. Zheng H, Ford BN, Bergamino M, Kuplicki R, Hunt PW, Bodurka J, Teague TK, Irwin MR, Yolken RH, Paulus MP, Savitz J. A hidden menace? Cytomegalovirus infection is associated with reduced cortical gray matter volume in major depressive disorder. Mol Psychiatry. 2021 08; 26(8):4234-4244. PMID: 33223520.
      Citations: 2     Fields:    Translation:Humans
    11. Le TT, Savitz J, Suzuki H, Misaki M, Teague TK, White BC, Marino JH, Wiley G, Gaffney PM, Drevets WC, McKinney BA, Bodurka J. Correction: Identification and replication of RNA-Seq gene network modules associated with depression severity. Transl Psychiatry. 2020 08 12; 10(1):282. PMID: 32788574.
      Citations:    Fields:    
    12. Brett BL, Savitz J, Nitta M, España L, Teague TK, Nelson LD, McCrea MA, Meier TB. Systemic inflammation moderates the association of prior concussion with hippocampal volume and episodic memory in high school and collegiate athletes. Brain Behav Immun. 2020 10; 89:380-388. PMID: 32717401.
      Citations: 1     Fields:    Translation:Humans
    13. Meier TB, Huber DL, Bohorquez-Montoya L, Nitta ME, Savitz J, Teague TK, Bazarian JJ, Hayes RL, Nelson LD, McCrea MA. A Prospective Study of Acute Blood-Based Biomarkers for Sport-Related Concussion. Ann Neurol. 2020 06; 87(6):907-920. PMID: 32215965.
      Citations: 8     Fields:    Translation:Humans
    14. Ford BN, Teague TK, Bayouth M, Yolken RH, Bodurka J, Irwin MR, Paulus MP, Savitz J. Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection. Brain Behav Immun. 2020 07; 87:795-803. PMID: 32209361.
      Citations: 1     Fields:    Translation:HumansCells
    15. Meier TB, Nitta ME, Teague TK, Nelson LD, McCrea MA, Savitz J. Prospective study of the effects of sport-related concussion on serum kynurenine pathway metabolites. Brain Behav Immun. 2020 07; 87:715-724. PMID: 32147388.
      Citations: 4     Fields:    Translation:Humans
    16. Burrows K, Stewart JL, Antonacci C, Kuplicki R, Thompson K, Taylor A, Teague TK, Paulus MP. Association of poorer dietary quality and higher dietary inflammation with greater symptom severity in depressed individuals with appetite loss. J Affect Disord. 2020 02 15; 263:99-106. PMID: 31818803.
      Citations: 5     Fields:    Translation:Humans
    17. Cosgrove KT, Burrows K, Avery JA, Kerr KL, DeVille DC, Aupperle RL, Teague TK, Drevets WC, Simmons WK. Appetite change profiles in depression exhibit differential relationships between systemic inflammation and activity in reward and interoceptive neurocircuitry. Brain Behav Immun. 2020 01; 83:163-171. PMID: 31604141.
      Citations: 5     Fields:    Translation:Humans
    18. Nitta ME, Savitz J, Nelson LD, Teague TK, Hoelzle JB, McCrea MA, Meier TB. Acute elevation of serum inflammatory markers predicts symptom recovery after concussion. Neurology. 2019 07 30; 93(5):e497-e507. PMID: 31270219.
      Citations: 14     Fields:    Translation:Humans
    19. Ford BN, Yolken RH, Aupperle RL, Teague TK, Irwin MR, Paulus MP, Savitz J. Association of Early-Life Stress With Cytomegalovirus Infection in Adults With Major Depressive Disorder. JAMA Psychiatry. 2019 05 01; 76(5):545-547. PMID: 30840037.
      Citations: 6     Fields:    Translation:Humans
    20. Marino JH, Teague TK. The Immune System as a Sensor and Regulator of Stress: Implications in Human Development and Disease, in Biobehavioral Markers in Risk and Resilience Research. Emerging Issues in Family and Individual Resilience (Harrist, AW, Gardner, BC, Eds.). 2019; 1-11. View Publication.
    21. Le TT, Savitz J, Suzuki H, Misaki M, Teague TK, White BC, Marino JH, Wiley G, Gaffney PM, Drevets WC, McKinney BA, Bodurka J. Identification and replication of RNA-Seq gene network modules associated with depression severity. Transl Psychiatry. 2018 09 05; 8(1):180. PMID: 30185774.
      Citations: 13     Fields:    Translation:HumansCells
    22. Simmons WK, Burrows K, Avery JA, Kerr KL, Taylor A, Bodurka J, Potter W, Teague TK, Drevets WC. Appetite changes reveal depression subgroups with distinct endocrine, metabolic, and immune states. Mol Psychiatry. 2020 07; 25(7):1457-1468. PMID: 29899546.
      Citations: 25     Fields:    Translation:Humans
    23. Ford BN, Yolken RH, Dickerson FB, Teague TK, Irwin MR, Paulus MP, Savitz J. Reduced immunity to measles in adults with major depressive disorder. Psychol Med. 2019 01; 49(2):243-249. PMID: 29552990.
      Citations: 9     Fields:    Translation:Humans
    24. Savitz JB, Teague TK, Misaki M, Macaluso M, Wurfel BE, Meyer M, Drevets D, Yates W, Gleason O, Drevets WC, Preskorn SH. Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, randomized, placebo-controlled, phase IIA clinical trial. Transl Psychiatry. 2018 01 24; 8(1):27. PMID: 29362444.
      Citations: 35     Fields:    Translation:HumansCTClinical Trials
    25. Meier TB, Drevets WC, Teague TK, Wurfel BE, Mueller SC, Bodurka J, Dantzer R, Savitz J. Kynurenic acid is reduced in females and oral contraceptive users: Implications for depression. Brain Behav Immun. 2018 Jan; 67:59-64. PMID: 28867283.
      Citations: 13     Fields:    Translation:Humans
    26. Cho HJ, Savitz J, Dantzer R, Teague TK, Drevets WC, Irwin MR. Sleep disturbance and kynurenine metabolism in depression. J Psychosom Res. 2017 08; 99:1-7. PMID: 28712413.
      Citations: 16     Fields:    Translation:Humans
    27. Wurfel BE, Drevets WC, Bliss SA, McMillin JR, Suzuki H, Ford BN, Morris HM, Teague TK, Dantzer R, Savitz JB. Serum kynurenic acid is reduced in affective psychosis. Transl Psychiatry. 2017 05 02; 7(5):e1115. PMID: 28463241.
      Citations: 25     Fields:    Translation:HumansCells
    28. Meier TB, Lancaster MA, Mayer AR, Teague TK, Savitz J. Abnormalities in Functional Connectivity in Collegiate Football Athletes with and without a Concussion History: Implications and Role of Neuroactive Kynurenine Pathway Metabolites. J Neurotrauma. 2017 02 15; 34(4):824-837. PMID: 27618518.
      Citations: 7     Fields:    Translation:Humans
    29. Young KD, Drevets WC, Dantzer R, Teague TK, Bodurka J, Savitz J. Kynurenine pathway metabolites are associated with hippocampal activity during autobiographical memory recall in patients with depression. Brain Behav Immun. 2016 Aug; 56:335-42. PMID: 27091600.
      Citations: 24     Fields:    Translation:Humans
    30. Meier TB, Savitz J, Singh R, Teague TK, Bellgowan PS. Smaller Dentate Gyrus and CA2 and CA3 Volumes Are Associated with Kynurenine Metabolites in Collegiate Football Athletes. J Neurotrauma. 2016 07 15; 33(14):1349-57. PMID: 26493952.
      Citations: 10     Fields:    Translation:Humans
    31. Meier TB, Drevets WC, Wurfel BE, Ford BN, Morris HM, Victor TA, Bodurka J, Teague TK, Dantzer R, Savitz J. Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder. Brain Behav Immun. 2016 Mar; 53:39-48. PMID: 26546831.
      Citations: 45     Fields:    Translation:Humans
    32. Singh R, Savitz J, Teague TK, Polanski DW, Mayer AR, Bellgowan PS, Meier TB. Mood symptoms correlate with kynurenine pathway metabolites following sports-related concussion. J Neurol Neurosurg Psychiatry. 2016 06; 87(6):670-5. PMID: 26269650.
      Citations: 10     Fields:    Translation:Humans
    33. Savitz J, Dantzer R, Meier TB, Wurfel BE, Victor TA, McIntosh SA, Ford BN, Morris HM, Bodurka J, Teague TK, Drevets WC. Activation of the kynurenine pathway is associated with striatal volume in major depressive disorder. Psychoneuroendocrinology. 2015 Dec; 62:54-8. PMID: 26232650.
      Citations: 35     Fields:    Translation:Humans
    34. Gandhapudi SK, Tan C, Marino JH, Taylor AA, Pack CC, Gaikwad J, Van De Wiele CJ, Wren JD, Teague TK. IL-18 acts in synergy with IL-7 to promote ex vivo expansion of T lymphoid progenitor cells. J Immunol. 2015 Apr 15; 194(8):3820-8. PMID: 25780034.
      Citations: 11     Fields:    Translation:AnimalsCells
    35. Savitz J, Drevets WC, Wurfel BE, Ford BN, Bellgowan PS, Victor TA, Bodurka J, Teague TK, Dantzer R. Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder. Brain Behav Immun. 2015 May; 46:55-9. PMID: 25686798.
      Citations: 69     Fields:    Translation:Humans
    36. Duffy FD, Miller-Cribbs JE, Clancy GP, Van De Wiele CJ, Teague TK, Crow S, Kollaja EA, Fox MD. Changing the culture of a medical school by orienting students and faculty toward community medicine. Acad Med. 2014 Dec; 89(12):1630-5. PMID: 25162616.
      Citations: 6     Fields:    Translation:Humans
    37. Savitz J, Dantzer R, Wurfel BE, Victor TA, Ford BN, Bodurka J, Bellgowan PS, Teague TK, Drevets WC. Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder. Psychoneuroendocrinology. 2015 Feb; 52:200-11. PMID: 25486577.
      Citations: 44     Fields:    Translation:Humans
    38. Savitz J, Drevets WC, Smith CM, Victor TA, Wurfel BE, Bellgowan PS, Bodurka J, Teague TK, Dantzer R. Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder. Neuropsychopharmacology. 2015 Jan; 40(2):463-71. PMID: 25074636.
      Citations: 82     Fields:    Translation:HumansCells
    39. Singh R, Meier TB, Kuplicki R, Savitz J, Mukai I, Cavanagh L, Allen T, Teague TK, Nerio C, Polanski D, Bellgowan PS. Relationship of collegiate football experience and concussion with hippocampal volume and cognitive outcomes. JAMA. 2014 May 14; 311(18):1883-8. PMID: 24825643.
      Citations: 50     Fields:    Translation:Humans
    40. Savitz J, Preskorn S, Teague TK, Drevets D, Yates W, Drevets W. Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trial. BMJ Open. 2012; 2(1):e000643. PMID: 22357572.
      Citations: 25     Fields:    
    41. Tan C, Taylor AA, Coburn MZ, Marino JH, Van De Wiele CJ, Teague TK. Ten-color flow cytometry reveals distinct patterns of expression of CD124 and CD126 by developing thymocytes. BMC Immunol. 2011 Jun 20; 12:36. PMID: 21689450.
      Citations: 6     Fields:    Translation:AnimalsCells
    42. Teague TK, Tan C, Marino JH, Davis BK, Taylor AA, Huey RW, Van De Wiele CJ. CD28 expression redefines thymocyte development during the pre-T to DP transition. Int Immunol. 2010 May; 22(5):387-97. PMID: 20203098.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    43. Marino JH, Tan C, Taylor AA, Bentley C, Van De Wiele CJ, Ranne R, Paliotta M, Broughan TA, Teague TK. Differential IL-7 responses in developing human thymocytes. Hum Immunol. 2010 Apr; 71(4):329-33. PMID: 20074604.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    44. Marino JH, Tan C, Davis B, Han ES, Hickey M, Naukam R, Taylor A, Miller KS, Van De Wiele CJ, Teague TK. Disruption of thymopoiesis in ST6Gal I-deficient mice. Glycobiology. 2008 Sep; 18(9):719-26. PMID: 18535087.
      Citations: 10     Fields:    Translation:Animals
    45. Van de Wiele CJ, Marino JH, Tan C, Kneale HA, Weber J, Morelli JN, Davis BK, Taylor AA, Teague TK. Impaired thymopoiesis in interleukin-7 receptor transgenic mice is not corrected by Bcl-2. Cell Immunol. 2007 Nov-Dec; 250(1-2):31-9. PMID: 18321477.
      Citations: 7     Fields:    Translation:AnimalsCells
    46. Marino JH, Van De Wiele CJ, Everhart JM, Masengale R, Naukam RJ, Schniederjan MJ, Vo S, Teague TK. Attenuation of cytokine responsiveness during T cell development and differentiation. J Interferon Cytokine Res. 2006 Oct; 26(10):748-59. PMID: 17032169.
      Citations: 8     Fields:    Translation:AnimalsCells
    47. Van De Wiele CJ, Marino JH, Murray BW, Vo SS, Whetsell ME, Teague TK. Thymocytes between the beta-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation. J Immunol. 2004 Apr 01; 172(7):4235-44. PMID: 15034036.
      Citations: 45     Fields:    Translation:AnimalsCells
    48. Van De Wiele CJ, Marino JH, Whetsell ME, Vo SS, Masengale RM, Teague TK. Loss of interferon-induced Stat1 phosphorylation in activated T cells. J Interferon Cytokine Res. 2004 Mar; 24(3):169-78. PMID: 15035850.
      Citations: 8     Fields:    Translation:AnimalsCells
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