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Lester A Reinke

TitleProf Emeritus
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentCell Biology
AddressCPB 327
1110 N Stonewall Ave
Oklahoma City OK 73117
Phone405/271-6593 ext 47246
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    F06TW001538     (REINKE, LESTER A.)Jul 27, 1990
    NIH
    FACTORS AFFECTING ESR STUDIES OF FREE RADICALS IN VIVO
    Role: Principal Investigator
    R01AA007337     (REINKE, LESTER A.)Jul 1, 1987 - Jul 31, 2001
    NIH
    FREE RADICALS IN ALCOHOLIC LIVER INJURY
    Role: Principal Investigator
    R01CA030137     (REINKE, LESTER A.)Sep 1, 1980 - May 31, 1987
    NIH
    INFLUENCE OF ETHANOL ON CARCINOGEN ACTIVATION
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lee EG, Mickle-Kawar BM, Reinke LA, Gallucci RM. Estrogen suppresses heptatic I?B expression during short-term alcohol exposure. Inflamm Res. 2012 Oct; 61(10):1053-61. PMID: 22669179.
      Citations: 5     Fields:    Translation:Animals
    2. Gallucci RM, Sloan DK, O'Dell SJ, Reinke LA. Differential expression of liver interleukin-6 receptor-alpha in female versus male ethanol-consuming rats. Alcohol Clin Exp Res. 2004 Mar; 28(3):365-73. PMID: 15084893.
      Citations: 8     Fields:    Translation:Animals
    3. Towner RA, Mason RP, Reinke LA. In vivo detection of aflatoxin-induced lipid free radicals in rat bile. Biochim Biophys Acta. 2002 Oct 10; 1573(1):55-62. PMID: 12383942.
      Citations: 2     Fields:    Translation:Animals
    4. Reinke LA. Spin trapping evidence for alcohol-associated oxidative stress. Free Radic Biol Med. 2002 May 15; 32(10):953-7. PMID: 12008110.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    5. Rao DB, Moore DR, Reinke LA, Fechter LD. Free radical generation in the cochlea during combined exposure to noise and carbon monoxide: an electrophysiological and an EPR study. Hear Res. 2001 Nov; 161(1-2):113-22. PMID: 11744287.
      Citations: 2     Fields:    Translation:AnimalsPHPublic Health
    6. Jokelainen K, Reinke LA, Nanji AA. Nf-kappab activation is associated with free radical generation and endotoxemia and precedes pathological liver injury in experimental alcoholic liver disease. Cytokine. 2001 Oct 07; 16(1):36-9. PMID: 11669585.
      Citations: 16     Fields:    Translation:Animals
    7. Bailey SM, Reinke LA. Antioxidants and gadolinium chloride attenuate hepatic parenchymal and endothelial cell injury induced by low flow ischemia and reperfusion in perfused rat livers. Free Radic Res. 2000 Jun; 32(6):497-506. PMID: 10798715.
      Citations: 2     Fields:    Translation:AnimalsCells
    8. Reinke LA, Moore DR, Nanji AA. Pronounced hepatic free radical formation precedes pathological liver injury in ethanol-fed rats. Alcohol Clin Exp Res. 2000 Mar; 24(3):332-5. PMID: 10776670.
      Citations: 2     Fields:    Translation:Animals
    9. Reinke LA, Moore DR, Sang H, Janzen EG, Kotake Y. Aromatic hydroxylation in PBN spin trapping by hydroxyl radicals and cytochrome P-450. Free Radic Biol Med. 2000 Feb 01; 28(3):345-50. PMID: 10699745.
      Citations: 3     Fields:    Translation:AnimalsCells
    10. Bailey SM, Reinke LA. Effect of low flow ischemia-reperfusion injury on liver function. Life Sci. 2000; 66(11):1033-44. PMID: 10724450.
      Citations: 4     Fields:    Translation:Animals
    11. Kotake Y, Moore DR, Sang H, Reinke LA. Continuous monitoring of in vivo nitric oxide formation using EPR analysis in biliary flow. Nitric Oxide. 1999; 3(2):114-22. PMID: 10369181.
      Citations: 3     Fields:    Translation:Animals
    12. Reinke LA, Kotake Y, Moore DR, Nanji AA. Free radical formation during ketamine anesthesia in rats: a cautionary note. Free Radic Biol Med. 1998 Apr; 24(6):1002-6. PMID: 9607611.
      Citations: 5     Fields:    Translation:AnimalsCells
    13. Reinke LA, Moore DR, McCay PB. Mechanisms for metabolism of ethanol to 1-hydroxyethyl radicals in rat liver microsomes. Arch Biochem Biophys. 1997 Dec 01; 348(1):9-14. PMID: 9390169.
      Citations:    Fields:    Translation:AnimalsCells
    14. Reinke LA, Moore DR, McCay PB. Free radical formation in livers of rats treated acutely and chronically with alcohol. Alcohol Clin Exp Res. 1997 Jun; 21(4):642-6. PMID: 9194918.
      Citations: 3     Fields:    Translation:AnimalsCells
    15. Reinke LA, McCay PB. Spin trapping studies of alcohol-initiated radicals in rat liver: influence of dietary fat. J Nutr. 1997 05; 127(5 Suppl):899S-902S. PMID: 9164259.
      Citations: 2     Fields:    Translation:Animals
    16. Bailey SM, Fauconnet AL, Reinke LA. Comparison of salicylate and D-phenylalanine for detection of hydroxyl radicals in chemical and biological reactions. Redox Rep. 1997 Feb; 3(1):17-22. PMID: 27414767.
      Citations: 1     Fields:    
    17. Reinke LA, Moore DR, McCay PB. Degradation of DMPO adducts from hydroxyl and 1-hydroxyethyl radicals by rat liver microsomes. Free Radic Res. 1996 Dec; 25(6):467-74. PMID: 8951420.
      Citations: 3     Fields:    Translation:AnimalsCells
    18. Reinke LA, Moore DR, Kotake Y. Hepatic nitric oxide formation: spin trapping detection in biliary efflux. Anal Biochem. 1996 Dec 01; 243(1):8-14. PMID: 8954520.
      Citations: 2     Fields:    Translation:Animals
    19. Janzen EG, Chen JZ, Reinke LA, Yamashiro S. Inhibitory effect of phenyl N-terf-butyl nitrone on Kupffer cell phagocytosis. Redox Rep. 1996 Oct; 2(5):345-7. PMID: 27406416.
      Citations: 1     Fields:    
    20. Moore DR, Reinke LA, McCay PB. Metabolism of ethanol to 1-hydroxyethyl radicals in vivo: detection with intravenous administration of alpha-(4-pyridyl-1-oxide)-N-t-butylnitrone. Mol Pharmacol. 1995 Jun; 47(6):1224-30. PMID: 7603464.
      Citations: 1     Fields:    Translation:Animals
    21. Tanigawa T, Kotake Y, Tanigawa M, Reinke LA. Mutual contact of adherent polymorphonuclear leukocytes inhibits their generation of superoxide. Free Radic Res. 1995 Apr; 22(4):361-73. PMID: 7633566.
      Citations:    Fields:    Translation:HumansCells
    22. Reinke LA, Moore DR, Rau JM, McCay PB. Inorganic phosphate promotes redox cycling of iron in liver microsomes: effects on free radical reactions. Arch Biochem Biophys. 1995 Feb 01; 316(2):758-64. PMID: 7864631.
      Citations:    Fields:    Translation:AnimalsCells
    23. Reinke LA, Moore DR, Hague CM, McCay PB. Metabolism of ethanol to 1-hydroxyethyl radicals in rat liver microsomes: comparative studies with three spin trapping agents. Free Radic Res. 1994 Sep; 21(4):213-22. PMID: 7827693.
      Citations:    Fields:    Translation:AnimalsCells
    24. Kotake Y, Reinke LA, Tanigawa T, Koshida H. Determination of the rate of superoxide generation from biological systems by spin trapping: use of rapid oxygen depletion to measure the decay rate of spin adducts. Free Radic Biol Med. 1994 Sep; 17(3):215-23. PMID: 7982627.
      Citations: 2     Fields:    Translation:HumansCells
    25. Towner RA, Reinke LA, Janzen EG, Yamashiro S. In vivo magnetic resonance imaging study of Kupffer cell involvement in CCl4-induced hepatotoxicity in rats. Can J Physiol Pharmacol. 1994 May; 72(5):441-6. PMID: 7954070.
      Citations:    Fields:    Translation:AnimalsCells
    26. Reinke LA, Rau JM, McCay PB. Characteristics of an oxidant formed during iron (II) autoxidation. Free Radic Biol Med. 1994 Apr; 16(4):485-92. PMID: 8005533.
      Citations: 6     Fields:    Translation:Cells
    27. Reinke LA, Bailey SM, Rau JM, McCay PB. Oxygen radical formation in well-washed rat liver microsomes: spin trapping studies. Free Radic Res. 1994 Jan; 20(1):51-60. PMID: 8012521.
      Citations: 1     Fields:    Translation:AnimalsCells
    28. Tanigawa T, Kotake Y, Reinke LA. Spin trapping of superoxide radicals following stimulation of neutrophils with fMLP is temperature dependent. Free Radic Biol Med. 1993 Oct; 15(4):425-33. PMID: 8225024.
      Citations: 2     Fields:    Translation:HumansCells
    29. Tanigawa T, Kotake Y, Reinke LA. Spin trapping of superoxide from glass adherent polymorphonuclear leukocytes induced by N-formylmethionyl-leucyl-phenylalanine. Free Radic Res Commun. 1993; 19(2):101-10. PMID: 8225036.
      Citations: 1     Fields:    Translation:HumansCells
    30. Janzen EG, Zhdanov RI, Reinke LA. Metabolism of phenyl and alkyl spin adducts of PBN in rat hepatocytes. Rate dependence on size and type of addend group. Free Radic Res Commun. 1993; 19 Suppl 1:S157-62. PMID: 8282218.
      Citations:    Fields:    Translation:Animals
    31. Reinke LA. Commentary on 'Ethanol toxicity and oxidative stress' by S.C. Bondy. Toxicol Lett. 1992 Dec; 63(3):227-9. PMID: 1488773.
      Citations:    Fields:    Translation:AnimalsCells
    32. Reinke LA, Towner RA, Janzen EG. Spin trapping of free radical metabolites of carbon tetrachloride in vitro and in vivo: effect of acute ethanol administration. Toxicol Appl Pharmacol. 1992 Jan; 112(1):17-23. PMID: 1310168.
      Citations: 2     Fields:    Translation:AnimalsCells
    33. McCay PB, Reinke LA, Rau JM. Hydroxyl radicals are generated by hepatic microsomes during NADPH oxidation: relationship to ethanol metabolism. Free Radic Res Commun. 1992; 15(6):335-46. PMID: 1314760.
      Citations: 4     Fields:    Translation:AnimalsCells
    34. Towner RA, Reinke LA, Janzen EG, Yamashiro S. Enhancement of carbon tetrachloride-induced liver injury by a single dose of ethanol: proton magnetic resonance imaging (MRI) studies in vivo. Biochim Biophys Acta. 1991 Apr 15; 1096(3):222-30. PMID: 2018796.
      Citations: 1     Fields:    Translation:Animals
    35. Reinke LA, Janzen EG. Detection of spin adducts in blood after administration of carbon tetrachloride to rats. Chem Biol Interact. 1991; 78(2):155-65. PMID: 1645621.
      Citations:    Fields:    Translation:Animals
    36. Reinke LA, Kotake Y, McCay PB, Janzen EG. Spin-trapping studies of hepatic free radicals formed following the acute administration of ethanol to rats: in vivo detection of 1-hydroxyethyl radicals with PBN. Free Radic Biol Med. 1991; 11(1):31-9. PMID: 1657733.
      Citations: 6     Fields:    Translation:Animals
    37. Rau JM, Reinke LA, McCay PB. Direct observation of spin-trapped carbon dioxide radicals in hepatocytes exposed to carbon tetrachloride. Free Radic Res Commun. 1990; 9(3-6):197-204. PMID: 2167257.
      Citations: 1     Fields:    Translation:Animals
    38. Reinke LA, Rau JM, McCay PB. Possible roles of free radicals in alcoholic tissue damage. Free Radic Res Commun. 1990; 9(3-6):205-11. PMID: 2167258.
      Citations: 1     Fields:    Translation:AnimalsCells
    39. Reinke LA, Lai EK, McCay PB. Ethanol feeding stimulates trichloromethyl radical formation from carbon tetrachloride in liver. Xenobiotica. 1988 Nov; 18(11):1311-8. PMID: 3245227.
      Citations: 2     Fields:    Translation:AnimalsCells
    40. Sweeny DJ, Reinke LA. Sulfation of acetaminophen in isolated rat hepatocytes. Relationship to sulfate ion concentrations and intracellular levels of 3'-phosphoadenosine-5'-phosphosulfate. Drug Metab Dispos. 1988 Sep-Oct; 16(5):712-5. PMID: 2906595.
      Citations: 4     Fields:    Translation:AnimalsCells
    41. Reinke LA, Lai EK, DuBose CM, McCay PB. Reactive free radical generation in vivo in heart and liver of ethanol-fed rats: correlation with radical formation in vitro. Proc Natl Acad Sci U S A. 1987 Dec; 84(24):9223-7. PMID: 2827172.
      Citations: 22     Fields:    Translation:AnimalsCells
    42. Reinke LA, Tupper JS, Smith PR, Sweeny DJ. Diminished pentose cycle flux in perfused livers of ethanol-fed rats. Mol Pharmacol. 1987 Jun; 31(6):631-7. PMID: 3600608.
      Citations: 1     Fields:    Translation:AnimalsCells
    43. Sweeny DJ, Reinke LA. Metabolism of benzo[a]pyrene in the perfused rat liver: factors affecting the release of phenolic metabolites into the bile and perfusate. Carcinogenesis. 1987 Jun; 8(6):779-83. PMID: 3608074.
      Citations: 1     Fields:    Translation:Animals
    44. Reinke LA, Nakamura M, Logan L, Christensen HD, Carney JM. In vivo and in vitro 1-methylxanthine metabolism in the rat. Evidence that the dehydrogenase form of xanthine oxidase predominates in intact perfused liver. Drug Metab Dispos. 1987 May-Jun; 15(3):295-9. PMID: 2886302.
      Citations:    Fields:    Translation:AnimalsCells
    45. Sweeny DJ, Reinke LA. Effect of ethanol feeding on hepatic microsomal UDP-glucuronyltransferase activity. Biochem Pharmacol. 1987 Apr 15; 36(8):1381-3. PMID: 3109441.
      Citations: 1     Fields:    Translation:AnimalsCells
    46. Kauffman FC, Evans RK, Jerkins AA, Reinke LA, Conway JG, Thurman RG. Maintenance of nicotinamide dinucleotide phosphate content and oxidation-reduction state during mixed-function oxidation of p-nitroanisole in isolated perfused livers of various species. Biochem Pharmacol. 1987 Apr 01; 36(7):1083-90. PMID: 3566803.
      Citations: 1     Fields:    Translation:AnimalsCells
    47. Reinke LA, Tupper JS, Sweeny DJ. 7-ethoxycoumarin O-deethylation in perfused livers from ethanol-fed rats: evidence for an important role of mitochondrial reducing equivalents. Pharmacology. 1987; 34(2-3):167-75. PMID: 3108908.
      Citations:    Fields:    Translation:AnimalsCells
    48. Reinke LA, Moyer MJ, Notley KA. Diminished rates of glucuronidation and sulfation in perfused rat liver after chronic ethanol administration. Biochem Pharmacol. 1986 Feb 01; 35(3):439-47. PMID: 3081005.
      Citations: 1     Fields:    Translation:AnimalsCells
    49. Belinsky SA, Reinke LA, Scholz R, Kauffman FC, Thurman RG. Rates of pentose cycle flux in perfused rat liver. Evaluation of the role of reducing equivalents from the pentose cycle for mixed-function oxidation. Mol Pharmacol. 1985 Oct; 28(4):371-6. PMID: 4058419.
      Citations:    Fields:    Translation:AnimalsCells
    50. Reinke LA, Moyer MJ. p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol. Drug Metab Dispos. 1985 Sep-Oct; 13(5):548-52. PMID: 2865101.
      Citations: 61     Fields:    Translation:AnimalsCells
    51. Reinke LA, Sexter SH, Rikans LE. Comparison of ethanol and imidazole pretreatments on hepatic monooxygenase activities in the rat. Res Commun Chem Pathol Pharmacol. 1985 Jan; 47(1):97-106. PMID: 3983472.
      Citations: 2     Fields:    Translation:AnimalsCells
    52. Reinke LA, Harmon T, Belinsky SA, Kauffman FC, Thurman RG. p-Nitroanisole O-demethylation in perfused hamster liver. High rates of pentose cycle-independent mixed-function oxidation. Biochem Pharmacol. 1984 Apr 15; 33(8):1315-21. PMID: 6712737.
      Citations:    Fields:    Translation:AnimalsCells
    53. Reinke LA, Kauffman FC, Belinsky SA, Thurman RG. Inhibition of p-nitroanisole O-demethylation in perfused rat liver by potassium cyanide. Arch Biochem Biophys. 1983 Aug; 225(1):313-9. PMID: 6311107.
      Citations:    Fields:    Translation:AnimalsCells
    54. Reinke LA, Kauffman FC, Belinsky SA, Thurman RG. Effects of ethanol and sorbitol on mixed-function oxidation in perfused rat livers. Pharmacol Biochem Behav. 1983; 18 Suppl 1:289-94. PMID: 6634842.
      Citations:    Fields:    Translation:AnimalsCells
    55. Reinke LA, McManus P, Kauffman FC, Thurman RG. Benzo(a)pyrene phenol production by perfused rat liver and its inhibition by ethanol. Cancer Res. 1982 May; 42(5):1681-5. PMID: 6279282.
      Citations:    Fields:    Translation:AnimalsCells
    56. Reinke LA, Belinsky SA, Kauffman FC, Evans RK, Thurman RG. Regulation of NADPH-dependent mixed-function oxidation in perfused livers. Comparative studies with sorbitol and ethanol. Biochem Pharmacol. 1982 Apr 15; 31(8):1621-8. PMID: 7092954.
      Citations:    Fields:    Translation:AnimalsCells
    57. Thurman RG, Reinke LA, Belinsky S, Evans RK, Kauffman FC. Co-regulation of the mixed-function oxidation of p-nitroanisole and glucuronidation of p-nitrophenol in the perfused rat liver by carbohydrate reserves. Arch Biochem Biophys. 1981 Jun; 209(1):137-42. PMID: 7283432.
      Citations: 4     Fields:    Translation:Animals
    58. Sonawane BR, Yaffe SJ, Reinke LA, Thurman RG. Postnatal development of mixed-function oxidation and conjugation in hemoglobin-free perfused rat liver. J Pharmacol Exp Ther. 1981 Mar; 216(3):473-8. PMID: 6782237.
      Citations:    Fields:    Translation:AnimalsCells
    59. Belinsky SA, Reinke LA, Kauffman FC, Thurman RG. Inhibition of mixed-function oxidation of p-nitroanisole in perfused rat liver by 2,4-dinitrophenol. Arch Biochem Biophys. 1980 Oct 01; 204(1):207-13. PMID: 7425638.
      Citations:    Fields:    Translation:AnimalsCells
    60. Reinke LA, Kauffman FC, Belinsky SA, Thurman RG. Interactions between ethanol metabolism and mixed-function oxidation in perfused rat liver: inhibition of p-nitroanisole O-demethylation. J Pharmacol Exp Ther. 1980 Apr; 213(1):70-8. PMID: 6987376.
      Citations: 2     Fields:    Translation:AnimalsCells
    61. Reinke LA, Kauffman FC, Thurman RG. Stimulation of p-nitroanisole O-demethylation in perfused livers by xylitol and sorbitol. Biochem Pharmacol. 1980 Mar 01; 29(5):813-9. PMID: 20227961.
      Citations: 3     Fields:    Translation:Animals
    62. Reinke LA, Belinsky SA, Kauffman FC, Thurman RG. Mechanism of inhibition of mixed-function oxidation by ethanol. Adv Exp Med Biol. 1980; 132:151-61. PMID: 7424703.
      Citations:    Fields:    Translation:AnimalsCells
    63. Reinke LA, Kauffman FC, Thurman RG. Stimulation of p-nitroanisole O-demethylation by ethanol in perfused livers from fasted rats. J Pharmacol Exp Ther. 1979 Oct; 211(1):133-9. PMID: 490314.
      Citations:    Fields:    Translation:AnimalsCells
    64. Reinke LA, Thurman RG, Kauffman FC. Oxidation-reduction state of free NADP+ during mixed-function oxidation in perfused rat livers--Evaluation of the assumptions of near equilibrium by comparisons of surface fluorescence changes and calculated NADP+:NADPH ratios. Biochem Pharmacol. 1979 Aug 01; 28(15):2381-7. PMID: 40558.
      Citations:    Fields:    Translation:AnimalsCells
    65. Reinke LA, Kauffman FC, Evans RK, Belinsky SA, Thurman RG. p-Nitrophenol conjugation in perfused livers from normal and phenobarbital-treated rats: influence of nutritional state. Res Commun Chem Pathol Pharmacol. 1979 Jan; 23(1):185-93. PMID: 108780.
      Citations: 1     Fields:    Translation:Animals
    66. Reinke LA, Stohs SJ, Rosenberg H. Increased aryl hydrocarbon hydroxylase activity in hepatic microsomes from streptozotocin-diabetic female rats. Xenobiotica. 1978 Dec; 8(12):769-78. PMID: 153061.
      Citations: 3     Fields:    Translation:AnimalsCells
    67. Reinke LA, Stohs SJ, Rosenberg H. Altered activity of hepatic mixed-function mono-oxygenase enzymes in streptozotocin-induced diabetic rats. Xenobiotica. 1978 Oct; 8(10):611-9. PMID: 152519.
      Citations: 11     Fields:    Translation:AnimalsCells
    68. Reinke LA, Rosenberg H, Stohs SJ. Altered metabolism of androstenedione by hepatic microsomes from streptozotocin-diabetic male rats. Res Commun Chem Pathol Pharmacol. 1978 Mar; 19(3):445-52. PMID: 653101.
      Citations:    Fields:    Translation:AnimalsCells
    69. Reinke LA, Rosenberg H, Stohs SJ. Induction of rat hepatic mixed function monooxygenases by levamisole. Res Commun Chem Pathol Pharmacol. 1976 Oct; 15(2):397-400. PMID: 981799.
      Citations:    Fields:    Translation:Animals
    70. Reinke LA, O'Connor MF, Piepho RW, Stohs SJ. A comparison of the inductive effects of phenobarbital, methaqualone, and methyprylon on hepatic mixed function oxidase enzymes in the rat. Res Commun Chem Pathol Pharmacol. 1975 May; 11(1):45-53. PMID: 239443.
      Citations: 2     Fields:    Translation:AnimalsCells
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