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Louis Vincent Lepak

InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentRehabilitation Sciences Tulsa
AddressOUTSC 2H33
4502 E 41st St
Tulsa OK 74135
ORCID ORCID Icon0000-0002-8144-7394 Additional info
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    HR21-164     (Yang, Y)Nov 1, 2021 - Oct 31, 2024
    Oklahoma Center for the Advancement of Science and Technology
    Multimodal integration of concurrent high-density EEG-fMRI with diffusion and anatomical MRI to determine dynamic information flow in brain circuits – an application to hemiparetic stroke.
    Role Description: Movement impairments that occur after a unilateral or hemiparetic stroke greatly affect a survivor’s ability to implement activities of daily living. Despite the development of multiple clinical interventions for motor recovery after stroke, rehabilitation treatments are only minimally effective in individuals with moderate-to-severe motor impairments. This is due to remaining gaps in our understanding of neural mechanisms driving movement impairments post-stroke that limit the creation of new approaches for neurorehabilitation. Recent studies, including ours, demonstrate that non-invasive brain stimulation, such as transcranial direct current stimulation (tDCS), can improve upper limb function in moderately-to-severely impaired individuals. However, the neural mechanism underlying this effect is yet to be explored. Thus, understanding of neural mechanisms underlying i) movement impairments and ii) the effects of tDCS can be crucial to the future development of targeted physical therapeutic interventions on improving motor functions post-stroke.
    Role: Co-I

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Williamson JN, Sikora WA, James SA, Parmar NJ, Lepak LV, Cheema CF, Refai HH, Wu DH, Sidorov EV, Dewald JPA, Yang Y. Cortical Reorganization of Early Somatosensory Processing in Hemiparetic Stroke. J Clin Med. 2022 Oct 31; 11(21). PMID: 36362680; PMCID: PMC9654771.
    2. Ciro CA, James SA, McGuire H, Lepak V, Dresser S, Costner-Lark A, Robinson W, Fritz T. Natural, longitudinal recovery of adults with COVID-19 using standardized rehabilitation measures. Front Aging Neurosci. 2022; 14:958744. PMID: 36092810; PMCID: PMC9452908.
      Citations: 1     
    3. Wang H, Ghazi M, Chandrashekhar R, Rippetoe J, Duginski GA, Lepak LV, Milhan LR, James SA. User Participatory Design of a Wearable Focal Vibration Device for Home-Based Stroke Rehabilitation. Sensors (Basel). 2022 Apr 26; 22(9). PMID: 35590997.
      Citations:    Fields:    Translation:Humans
    4. . Localized Vibration: Effects On Flexibility. Health, Sports, & Rehabilitation Medicine. 2020; 21(4):231-237. View Publication.
    5. . Avoidable & Inevitable? Skin Failure: The Kennedy Terminal Lesion. Journal of Legal Nurse Consulting. 2012; 23(1):24-27. View Publication.
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