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Steven Dwight Chernausek

TitleProf,Clin
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentDept of Pediatrics
AddressOUCPB 4500
1200 N Phillips Ave
Oklahoma City OK 73104
Phone405/271-8001
Fax0
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    Collapse Research 
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    R29NS025354     (CHERNAUSEK, STEVEN D)Apr 1, 1987 - Oct 1, 1992
    NIH
    SOMATOMEDINS AND BRAIN DEVELOPMENT
    Role: Principal Investigator

    R01DK089034     (CHERNAUSEK, STEVEN D)Aug 4, 2010 - May 31, 2017
    NIH
    Prenatal Conditions and the Pathway to Obesity and Diabetes in Children
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Shah KB, Chernausek SD, Garman LD, Pezant NP, Plows JF, Kharoud HK, Demerath EW, Fields DA. Human Milk Exosomal MicroRNA: Associations with Maternal Overweight/Obesity and Infant Body Composition at 1 Month of Life. Nutrients. 2021 Mar 27; 13(4). PMID: 33801634.
      Citations:    Fields:    
    2. Srinivasan S, Chen L, Todd J, Divers J, Gidding S, Chernausek S, Gubitosi-Klug RA, Kelsey MM, Shah R, Black MH, Wagenknecht LE, Manning A, Flannick J, Imperatore G, Mercader JM, Dabelea D, Florez JC. The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium. Diabetes. 2021 Apr; 70(4):996-1005. PMID: 33479058.
      Citations:    Fields:    
    3. Jiang S, Teague AM, Tryggestad JB, Lyons TJ, Chernausek SD. Fetal circulating human resistin increases in diabetes during pregnancy and impairs placental mitochondrial biogenesis. Mol Med. 2020 08 06; 26(1):76. PMID: 32762639.
      Citations:    Fields:    
    4. Shah KB, Chernausek SD, Teague AM, Bard DE, Tryggestad JB. Maternal diabetes alters microRNA expression in fetal exosomes, human umbilical vein endothelial cells and placenta. Pediatr Res. 2021 Apr; 89(5):1157-1163. PMID: 32663836.
      Citations: 2     Fields:    
    5. Jiang S, Teague AM, Tryggestad JB, Jensen ME, Chernausek SD. Role of metformin in epigenetic regulation of placental mitochondrial biogenesis in maternal diabetes. Sci Rep. 2020 05 20; 10(1):8314. PMID: 32433500.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    6. Tryggestad JB, Chernausek SD. BMI changes through childhood: the impact on puberty, linear growth and hormonal regulation. Pediatr Res. 2020 07; 88(1):11-13. PMID: 32299087.
      Citations:    Fields:    Translation:Humans
    7. Arslanian S, El Ghormli L, Haymond MH, Chan CL, Chernausek SD, Gandica RG, Gubitosi-Klug R, Levitsky LL, Siska M, Willi SM. Beta cell function and insulin sensitivity in obese youth with maturity onset diabetes of youth mutations vs type 2 diabetes in TODAY: Longitudinal observations and glycemic failure. Pediatr Diabetes. 2020 06; 21(4):575-585. PMID: 32064729.
      Citations:    Fields:    
    8. Tryggestad JB, Teague AM, Sparling DP, Jiang S, Chernausek SD. Macrophage-Derived microRNA-155 Increases in Obesity and Influences Adipocyte Metabolism by Targeting Peroxisome Proliferator-Activated Receptor Gamma. Obesity (Silver Spring). 2019 11; 27(11):1856-1864. PMID: 31531958.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    9. Alexander J, Teague AM, Chen J, Aston CE, Leung YK, Chernausek S, Simmons RA, Pinney SE. Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy. PLoS One. 2018; 13(2):e0190698. PMID: 29470513.
      Citations: 11     Fields:    Translation:HumansCells
    10. Murray PG, Clayton PE, Chernausek SD. A genetic approach to evaluation of short stature of undetermined cause. Lancet Diabetes Endocrinol. 2018 07; 6(7):564-574. PMID: 29397377.
      Citations: 8     Fields:    Translation:Humans
    11. Jiang S, Teague AM, Tryggestad JB, Aston CE, Lyons T, Chernausek SD. Effects of maternal diabetes and fetal sex on human placenta mitochondrial biogenesis. Placenta. 2017 Sep; 57:26-32. PMID: 28864016.
      Citations: 11     Fields:    Translation:Humans
    12. Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, Lippincott MF, Singh SS, Patel N, Jing JW, Law JR, Ferraro N, Verloes A, Rauch A, Steindl K, Zweier M, Scheer I, Sato D, Okamoto N, Jacobsen C, Tryggestad J, Chernausek S, Schimmenti LA, Brasseur B, Cesaretti C, García-Ortiz JE, Buitrago TP, Silva OP, Hoffman JD, Mühlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM, Lin AE, Katsanis N, Jones PL, Crowley WF, Davis EE, FitzPatrick DR, Talkowski ME. Corrigendum: SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nat Genet. 2017 05 26; 49(6):969. PMID: 28546579.
      Citations:    Fields:    
    13. Jiang S, Teague AM, Tryggestad JB, Chernausek SD. Role of microRNA-130b in placental PGC-1a/TFAM mitochondrial biogenesis pathway. Biochem Biophys Res Commun. 2017 06 03; 487(3):607-612. PMID: 28433632.
      Citations: 8     Fields:    Translation:HumansCells
    14. Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, Lippincott MF, Singh SS, Patel N, Jing JW, Law JR, Ferraro N, Verloes A, Rauch A, Steindl K, Zweier M, Scheer I, Sato D, Okamoto N, Jacobsen C, Tryggestad J, Chernausek S, Schimmenti LA, Brasseur B, Cesaretti C, García-Ortiz JE, Buitrago TP, Silva OP, Hoffman JD, Mühlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM, Lin AE, Katsanis N, Jones PL, Crowley WF, Davis EE, FitzPatrick DR, Talkowski ME. SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nat Genet. 2017 Feb; 49(2):238-248. PMID: 28067909.
      Citations: 36     Fields:    Translation:Humans
    15. Tryggestad JB, Vishwanath A, Jiang S, Mallappa A, Teague AM, Takahashi Y, Thompson DM, Chernausek SD. Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. Clin Sci (Lond). 2016 11 01; 130(21):1955-67. PMID: 27562513.
      Citations: 16     Fields:    Translation:HumansCells
    16. Copeland KC, Chernausek S. Mini-Puberty and Growth. Pediatrics. 2016 07; 138(1). PMID: 27283014.
      Citations: 6     Fields:    Translation:Humans
    17. Chernausek SD, Arslanian S, Caprio S, Copeland KC, El ghormli L, Kelsey MM, Koontz MB, Orsi CM, Wilfley D. Relationship Between Parental Diabetes and Presentation of Metabolic and Glycemic Function in Youth With Type 2 Diabetes: Baseline Findings From the TODAY Trial. Diabetes Care. 2016 Jan; 39(1):110-7. PMID: 26577415.
      Citations: 10     Fields:    Translation:HumansCells
    18. Ziegler EE, Fields DA, Chernausek SD, Steenhout P, Grathwohl D, Jeter JM, Nelson SE, Haschke F. Adequacy of Infant Formula With Protein Content of 1.6 g/100 kcal for Infants Between 3 and 12 Months. J Pediatr Gastroenterol Nutr. 2015 Nov; 61(5):596-603. PMID: 26154030.
      Citations: 7     Fields:    Translation:HumansAnimals
    19. Teague AM, Fields DA, Aston CE, Short KR, Lyons TJ, Chernausek SD. Cord blood adipokines, neonatal anthropometrics and postnatal growth in offspring of Hispanic and Native American women with diabetes mellitus. Reprod Biol Endocrinol. 2015 Jun 26; 13:68. PMID: 26111704.
      Citations: 14     Fields:    Translation:Humans
    20. Backeljauw PF, Bondy C, Chernausek SD, Cernich JT, Cole DA, Fasciano LP, Foodim J, Hawley S, Hong DS, Knickmeyer RC, Kruszka P, Lin AE, Lippe BM, Lorigan GA, Maslen CL, Mauras N, Page DC, Pemberton VL, Prakash SK, Quigley CA, Ranallo KC, Reiss AL, Sandberg DE, Scurlock C, Silberbach M. Proceedings from the Turner Resource Network symposium: the crossroads of health care research and health care delivery. . 2015 Sep; 167A(9):1962-71. PMID: 25920614.
      Citations:    
    21. Fields DA, Teague AM, Short KR, Chernausek SD. Evaluation of DXA vs. MRI for body composition measures in 1-month olds. Pediatr Obes. 2015 Oct; 10(5):e8-10. PMID: 25820269.
      Citations: 4     Fields:    Translation:Humans
    22. Short KR, Teague AM, Fields DA, Lyons T, Chernausek SD. Lower resting energy expenditure and fat oxidation in Native American and Hispanic infants born to mothers with diabetes. J Pediatr. 2015 Apr; 166(4):884-9. PMID: 25648295.
      Citations: 6     Fields:    Translation:Humans
    23. Chernausek SD. Whole exome sequencing in short stature: finding needles in the haystack. Horm Res Paediatr. 2014; 82(1):1-2. PMID: 25034399.
      Citations:    Fields:    Translation:Humans
    24. Xanthakos SA, Crimmins NA, Chernausek SD. Abnormalities in the growth hormone axis and risk of nonalcoholic steatohepatitis: active player or innocent bystander? J Pediatr. 2014 Jul; 165(1):12-4. PMID: 24793205.
      Citations: 1     Fields:    Translation:Humans
    25. Backeljauw PF, Kuntze J, Frane J, Calikoglu AS, Chernausek SD. Adult and near-adult height in patients with severe insulin-like growth factor-I deficiency after long-term therapy with recombinant human insulin-like growth factor-I. Horm Res Paediatr. 2013; 80(1):47-56. PMID: 23887143.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    26. Tryggestad JB, Li S, Chernausek SD. Hypogonadotropic hypogonadism presenting with arhinia: a case report. J Med Case Rep. 2013 Feb 22; 7:52. PMID: 23432817.
      Citations: 1     Fields:    
    27. Creighton S, Chernausek SD, Romao R, Ransley P, Salle JP. Timing and nature of reconstructive surgery for disorders of sex development - introduction. J Pediatr Urol. 2012 Dec; 8(6):602-10. PMID: 23146296.
      Citations: 8     Fields:    Translation:Humans
    28. Shankar RK, Rutter MJ, Chernausek SD, Samuels PJ, Mo JQ, Rutter MM. Medullary thyroid cancer in a 9-week-old infant with familial MEN 2B: Implications for timing of prophylactic thyroidectomy. Int J Pediatr Endocrinol. 2012 Sep 19; 2012(1):25. PMID: 22992277.
      Citations:    
    29. Kansra AR, Dolan LM, Martin LJ, Deka R, Chernausek SD. IGF receptor gene variants in normal adolescents: effect on stature. Eur J Endocrinol. 2012 Dec; 167(6):777-81. PMID: 22972910.
      Citations: 3     Fields:    Translation:Humans
    30. Wolfe-Christensen C, Fedele DA, Kirk K, Phillips TM, Mazur T, Mullins LL, Chernausek SD, Lakshmanan Y, Wisniewski AB. Degree of external genital malformation at birth in children with a disorder of sex development and subsequent caregiver distress. J Urol. 2012 Oct; 188(4 Suppl):1596-600. PMID: 22910249.
      Citations: 6     Fields:    Translation:Humans
    31. Backeljauw PF, Chernausek SD. The insulin-like growth factors and growth disorders of childhood. Endocrinol Metab Clin North Am. 2012 Jun; 41(2):265-82, v. PMID: 22682630.
      Citations: 7     Fields:    Translation:Humans
    32. Chernausek SD. Update: consequences of abnormal fetal growth. J Clin Endocrinol Metab. 2012 Mar; 97(3):689-95. PMID: 22238390.
      Citations: 24     Fields:    Translation:Humans
    33. Palmer BW, Wisniewski AB, Schaeffer TL, Mallappa A, Tryggestad JB, Krishnan S, Chalmers LJ, Copeland K, Chernausek SD, Reiner WG, Kropp BP. A model of delivering multi-disciplinary care to people with 46 XY DSD. J Pediatr Urol. 2012 Feb; 8(1):7-16. PMID: 22078657.
      Citations: 13     Fields:    Translation:Humans
    34. Chernausek SD. Criteria for treating children with idiopathic short stature: laboratory (biochemical). Horm Res Paediatr. 2011; 76 Suppl 3:18-20. PMID: 21912152.
      Citations:    Fields:    Translation:Humans
    35. Kirk KD, Fedele DA, Wolfe-Christensen C, Phillips TM, Mazur T, Mullins LL, Chernausek SD, Wisniewski AB. Parenting characteristics of female caregivers of children affected by chronic endocrine conditions: a comparison between disorders of sex development and type 1 diabetes mellitus. J Pediatr Nurs. 2011 Dec; 26(6):e29-36. PMID: 21911316.
      Citations: 9     Fields:    Translation:Humans
    36. Sisson SB, Broyles ST, Newton RL, Baker BL, Chernausek SD. TVs in the bedrooms of children: does it impact health and behavior? Prev Med. 2011 Feb; 52(2):104-8. PMID: 21130109.
      Citations: 15     Fields:    Translation:HumansPHPublic Health
    37. Fedele DA, Kirk K, Wolfe-Christensen C, Phillips TM, Mazur T, Mullins LL, Chernausek SD, Wisniewski AB. Primary caregivers of children affected by disorders of sex development: mental health and caregiver characteristics in the context of genital ambiguity and genitoplasty. Int J Pediatr Endocrinol. 2010; 2010:690674. PMID: 20628508.
      Citations:    
    38. Chernausek SD. Growth and development: how safe is growth hormone therapy for children? Nat Rev Endocrinol. 2010 May; 6(5):251-3. PMID: 20414318.
      Citations: 1     Fields:    Translation:Humans
    39. Schaeffer TL, Tryggestad JB, Mallappa A, Hanna AE, Krishnan S, Chernausek SD, Chalmers LJ, Reiner WG, Kropp BP, Wisniewski AB. An Evidence-Based Model of Multidisciplinary Care for Patients and Families Affected by Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency. Int J Pediatr Endocrinol. 2010; 2010:692439. PMID: 20339513.
      Citations:    
    40. Chernausek SD. Growth hormone-resistant syndromes: long-term follow-up. Endocr Dev. 2009; 14:135-42. PMID: 19293580.
      Citations: 1     Fields:    Translation:Humans
    41. Wisniewski AB, Chernausek SD. Gender in childhood obesity: family environment, hormones, and genes. Gend Med. 2009; 6 Suppl 1:76-85. PMID: 19318220.
      Citations: 52     Fields:    Translation:Humans
    42. Cohen P, Rogol AD, Deal CL, Saenger P, Reiter EO, Ross JL, Chernausek SD, Savage MO, Wit JM. Consensus statement on the diagnosis and treatment of children with idiopathic short stature: a summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop. J Clin Endocrinol Metab. 2008 Nov; 93(11):4210-7. PMID: 18782877.
      Citations: 138     Fields:    Translation:HumansPHPublic Health
    43. Chernausek S. Evaluation of an insulin-like growth factor I-based growth hormone dosing regimen for children with short stature. Nat Clin Pract Endocrinol Metab. 2007 Oct; 3(10):682-3. PMID: 17667897.
      Citations:    Fields:    
    44. Chernausek SD, Backeljauw PF, Frane J, Kuntze J, Underwood LE. Long-term treatment with recombinant insulin-like growth factor (IGF)-I in children with severe IGF-I deficiency due to growth hormone insensitivity. J Clin Endocrinol Metab. 2007 Mar; 92(3):902-10. PMID: 17192294.
      Citations: 48     Fields:    Translation:Humans
    45. Pinhas-Hamiel O, Chernausek SD, Zeitler P. Acute necrotizing pancreatitis in an adolescent with type 2 diabetes. Curr Opin Pediatr. 2006 Apr; 18(2):206-8. PMID: 16601505.
      Citations: 1     Fields:    Translation:Humans
    46. Backeljauw PF, Chernausek SD. Treatment of insulin-like growth factor deficiency with IGF-I: studies in humans. Horm Res. 2006; 65 Suppl 1:21-7. PMID: 16508330.
      Citations: 1     Fields:    Translation:Humans
    47. Chernausek SD. Mendelian genetic causes of the short child born small for gestational age. J Endocrinol Invest. 2006; 29(1 Suppl):16-20. PMID: 16615302.
      Citations: 4     Fields:    Translation:Humans
    48. Rutter MM, Markoff E, Clayton L, Akeno N, Zhao G, Clemens TL, Chernausek SD. Osteoblast-specific expression of insulin-like growth factor-1 in bone of transgenic mice induces insulin-like growth factor binding protein-5. Bone. 2005 Feb; 36(2):224-31. PMID: 15780948.
      Citations: 6     Fields:    Translation:AnimalsCells
    49. Chernausek SD. Treatment of short children born small for gestational age: US perspective, 2005. Horm Res. 2005; 64 Suppl 2:63-6. PMID: 16286774.
      Citations:    Fields:    Translation:Humans
    50. Clemens TL, Chernausek SD. Genetic strategies for elucidating insulin-like growth factor action in bone. Growth Horm IGF Res. 2004 Jun; 14(3):195-9. PMID: 15125880.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    51. Chernausek SD. Growth hormone treatment of short children born small for gestational age: a US perspective. Horm Res. 2004; 62 Suppl 3:124-7. PMID: 15539813.
      Citations:    Fields:    Translation:Humans
    52. Abuzzahab MJ, Schneider A, Goddard A, Grigorescu F, Lautier C, Keller E, Kiess W, Klammt J, Kratzsch J, Osgood D, Pfäffle R, Raile K, Seidel B, Smith RJ, Chernausek SD. IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation. N Engl J Med. 2003 Dec 04; 349(23):2211-22. PMID: 14657428.
      Citations: 111     Fields:    Translation:HumansCells
    53. Lee PA, Chernausek SD, Hokken-Koelega AC, Czernichow P. International Small for Gestational Age Advisory Board consensus development conference statement: management of short children born small for gestational age, April 24-October 1, 2001. Pediatrics. 2003 Jun; 111(6 Pt 1):1253-61. PMID: 12777538.
      Citations: 107     Fields:    Translation:Humans
    54. Zhang M, Faugere MC, Malluche H, Rosen CJ, Chernausek SD, Clemens TL. Paracrine overexpression of IGFBP-4 in osteoblasts of transgenic mice decreases bone turnover and causes global growth retardation. J Bone Miner Res. 2003 May; 18(5):836-43. PMID: 12733722.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    55. Chernausek SD. Development of a consensus statement on management of short children born small for gestational age. J Pediatr Endocrinol Metab. 2002 Dec; 15 Suppl 5:1275. PMID: 12510979.
      Citations:    Fields:    Translation:Humans
    56. Zhang M, Smith EP, Kuroda H, Banach W, Chernausek SD, Fagin JA. Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy. J Biol Chem. 2002 Jun 14; 277(24):21285-90. PMID: 11923290.
      Citations: 15     Fields:    Translation:AnimalsCells
    57. Bucuvalas JC, Chernausek SD. Growth hormone and cystic fibrosis: good for more than growth? J Pediatr. 2001 Nov; 139(5):616-8. PMID: 11713433.
      Citations: 1     Fields:    Translation:Humans
    58. Bucuvalas JC, Chernausek SD, Alfaro MP, Krug SK, Ritschel W, Wilmott RW. Effect of insulinlike growth factor-1 treatment in children with cystic fibrosis. J Pediatr Gastroenterol Nutr. 2001 Nov; 33(5):576-81. PMID: 11740232.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    59. Smith EP, Kamyar A, Niu W, Wang J, Cercek B, Chernausek SD, Fagin JA. IGF-binding protein-4 expression and IGF-binding protein-4 protease activity are regulated coordinately in smooth muscle during postnatal development and after vascular injury. Endocrinology. 2001 Oct; 142(10):4420-7. PMID: 11564706.
      Citations: 1     Fields:    Translation:AnimalsCells
    60. Chernausek SD. Managing the transition of adolescents with GH deficiency. J Endocrinol Invest. 2001 Oct; 24(9):676-80. PMID: 11716154.
      Citations:    Fields:    Translation:Humans
    61. Yakar S, Liu JL, Fernandez AM, Wu Y, Schally AV, Frystyk J, Chernausek SD, Mejia W, Le Roith D. Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity. Diabetes. 2001 May; 50(5):1110-8. PMID: 11334415.
      Citations: 77     Fields:    Translation:AnimalsCells
    62. Rosenfield RL, Bachrach LK, Chernausek SD, Gertner JM, Gottschalk M, Hardin DS, Pescovitz OH, Saenger P. Current age of onset of puberty. Pediatrics. 2000 Sep; 106(3):622-3. PMID: 11012339.
      Citations: 13     Fields:    Translation:Humans
    63. Zhao G, Monier-Faugere MC, Langub MC, Geng Z, Nakayama T, Pike JW, Chernausek SD, Rosen CJ, Donahue LR, Malluche HH, Fagin JA, Clemens TL. Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation. Endocrinology. 2000 Jul; 141(7):2674-82. PMID: 10875273.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    64. Chernausek SD, Attie KM, Cara JF, Rosenfeld RG, Frane J. Growth hormone therapy of Turner syndrome: the impact of age of estrogen replacement on final height. Genentech, Inc., Collaborative Study Group. J Clin Endocrinol Metab. 2000 Jul; 85(7):2439-45. PMID: 10902791.
      Citations: 25     Fields:    Translation:HumansCTClinical Trials
    65. Chernausek SD, Attie KM. Role of oestrogen therapy in the management of short stature in Turner syndrome. Acta Paediatr Suppl. 1999 Dec; 88(433):130-2. PMID: 10626564.
      Citations: 3     Fields:    Translation:Humans
    66. Ewton DZ, Coolican SA, Mohan S, Chernausek SD, Florini JR. Modulation of insulin-like growth factor actions in L6A1 myoblasts by insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5: a dual role for IGFBP-5. J Cell Physiol. 1998 Oct; 177(1):47-57. PMID: 9731744.
      Citations: 18     Fields:    Translation:HumansCells
    67. Schorry EK, Dietrich KN, Saal HM, Blough RI, Dey S, Chernausek S, Milatovich-Cherry A. Partial trisomy 1q with growth hormone deficiency and normal intelligence. Am J Med Genet. 1998 May 26; 77(4):257-60. PMID: 9600731.
      Citations: 2     Fields:    Translation:HumansCells
    68. Wang J, Niu W, Witte DP, Chernausek SD, Nikiforov YE, Clemens TL, Sharifi B, Strauch AR, Fagin JA. Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia. Endocrinology. 1998 May; 139(5):2605-14. PMID: 9564877.
      Citations: 19     Fields:    Translation:Animals
    69. Rosenfeld RG, Attie KM, Frane J, Brasel JA, Burstein S, Cara JF, Chernausek S, Gotlin RW, Kuntze J, Lippe BM, Mahoney CP, Moore WV, Saenger P, Johanson AJ. Growth hormone therapy of Turner's syndrome: beneficial effect on adult height. J Pediatr. 1998 Feb; 132(2):319-24. PMID: 9506648.
      Citations: 35     Fields:    Translation:HumansCTClinical Trials
    70. Wang J, Niu W, Nikiforov Y, Naito S, Chernausek S, Witte D, LeRoith D, Strauch A, Fagin JA. Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice. J Clin Invest. 1997 Sep 15; 100(6):1425-39. PMID: 9294108.
      Citations: 46     Fields:    Translation:AnimalsCells
    71. Brown DL, Kane CD, Chernausek SD, Greenhalgh DG. Differential expression and localization of insulin-like growth factors I and II in cutaneous wounds of diabetic and nondiabetic mice. Am J Pathol. 1997 Sep; 151(3):715-24. PMID: 9284820.
      Citations: 22     Fields:    Translation:Animals
    72. Bucuvalas JC, Horn JA, Chernausek SD. Resistance to growth hormone in children with chronic liver disease. Pediatr Transplant. 1997 Aug; 1(1):73-9. PMID: 10084790.
      Citations: 9     Fields:    Translation:Humans
    73. Goddard AD, Dowd P, Chernausek S, Geffner M, Gertner J, Hintz R, Hopwood N, Kaplan S, Plotnick L, Rogol A, Rosenfield R, Saenger P, Mauras N, Hershkopf R, Angulo M, Attie K. Partial growth-hormone insensitivity: the role of growth-hormone receptor mutations in idiopathic short stature. J Pediatr. 1997 Jul; 131(1 Pt 2):S51-5. PMID: 9255229.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    74. Kummer JL, Zawada WM, Freed CR, Chernausek SD, Heidenreich KA. Insulin-like growth factor binding proteins in fetal rat mesencephalic cultures: regulation by fibroblast growth factor and insulin-like growth factor I. Endocrinology. 1996 Aug; 137(8):3551-6. PMID: 8754786.
      Citations: 1     Fields:    Translation:AnimalsCells
    75. Bucuvalas JC, Horn JA, Slusher J, Alfaro MP, Chernausek SD. Growth hormone insensitivity in children with biliary atresia. J Pediatr Gastroenterol Nutr. 1996 Aug; 23(2):135-40. PMID: 8856579.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    76. Frank GR, Cheung PT, Horn JA, Alfaro MP, Smith EP, Chernausek SD. Predicting the growth response to growth hormone in patients with intrauterine growth retardation. Clin Endocrinol (Oxf). 1996 Jun; 44(6):679-85. PMID: 8759180.
      Citations:    Fields:    Translation:Humans
    77. Chernausek SD, Breen TJ, Frank GR. Linear growth in response to growth hormone treatment in children with short stature associated with intrauterine growth retardation: the National Cooperative Growth Study experience. J Pediatr. 1996 May; 128(5 Pt 2):S22-7. PMID: 8627464.
      Citations: 2     Fields:    Translation:Humans
    78. Chernausek SD, Smith CE, Duffin KL, Busby WH, Wright G, Clemmons DR. Proteolytic cleavage of insulin-like growth factor binding protein 4 (IGFBP-4). Localization of cleavage site to non-homologous region of native IGFBP-4. J Biol Chem. 1995 May 12; 270(19):11377-82. PMID: 7538115.
      Citations: 6     Fields:    Translation:AnimalsCells
    79. Cheung PT, Wu J, Banach W, Chernausek SD. Glucocorticoid regulation of an insulin-like growth factor-binding protein-4 protease produced by a rat neuronal cell line. Endocrinology. 1994 Oct; 135(4):1328-35. PMID: 7523095.
      Citations: 3     Fields:    Translation:AnimalsCells
    80. Smith EP, Lu L, Chernausek SD, Klein DJ. Insulin-like growth factor-binding protein-3 (IGFBP-3) concentration in rat Sertoli cell-conditioned medium is regulated by a pathway involving association of IGFBP-3 with cell surface proteoglycans. Endocrinology. 1994 Jul; 135(1):359-64. PMID: 7516869.
      Citations: 6     Fields:    Translation:AnimalsCells
    81. Chernausek SD, Murray MA, Cheung PT. Expression of insulin-like growth factor binding protein-4 (IGFBP-4) by rat neural cells--comparison to other IGFBPs. Regul Pept. 1993 Oct 20; 48(1-2):123-32. PMID: 7505459.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    82. Myers SE, Cheung PT, Handwerger S, Chernausek SD. Insulin-like growth factor-I (IGF-I) enhanced proteolysis of IGF-binding protein-4 in conditioned medium from primary cultures of human decidua: independence from IGF receptor binding. Endocrinology. 1993 Oct; 133(4):1525-31. PMID: 7691578.
      Citations: 4     Fields:    Translation:HumansCells
    83. Hopwood NJ, Hintz RL, Gertner JM, Attie KM, Johanson AJ, Baptista J, Kuntze J, Blizzard RM, Cara JF, Chernausek SD, et al. Growth response of children with non-growth-hormone deficiency and marked short stature during three years of growth hormone therapy. J Pediatr. 1993 Aug; 123(2):215-22. PMID: 8345416.
      Citations: 24     Fields:    Translation:HumansCTClinical Trials
    84. Murray MA, Dickson BA, Smith EP, Hoath SB, Chernausek SD. Epidermal growth factor stimulates insulin-like growth factor-binding protein-1 expression in the neonatal rat. Endocrinology. 1993 Jul; 133(1):159-65. PMID: 7686479.
      Citations:    Fields:    Translation:Animals
    85. Kaplowitz PB, Chernausek SD, Horn JA. Fingernail angle in girls with Ullrich-Turner syndrome. Am J Med Genet. 1993 Jun 15; 46(5):570-3. PMID: 8322823.
      Citations:    Fields:    Translation:Humans
    86. Bucuvalas JC, Horn JA, Carlsson L, Balistreri WF, Chernausek SD. Growth hormone insensitivity associated with elevated circulating growth hormone-binding protein in children with Alagille syndrome and short stature. J Clin Endocrinol Metab. 1993 Jun; 76(6):1477-82. PMID: 8501153.
      Citations: 9     Fields:    Translation:Humans
    87. Berg MA, Argente J, Chernausek S, Gracia R, Guevara-Aguirre J, Hopp M, Pérez-Jurado L, Rosenbloom A, Toledo SP, Francke U. Diverse growth hormone receptor gene mutations in Laron syndrome. Am J Hum Genet. 1993 May; 52(5):998-1005. PMID: 8488849.
      Citations: 17     Fields:    Translation:HumansCells
    88. Brar AK, Chernausek SD. Localization of insulin-like growth factor binding protein-4 expression in the developing and adult rat brain: analysis by in situ hybridization. J Neurosci Res. 1993 May 01; 35(1):103-14. PMID: 7685395.
      Citations: 8     Fields:    Translation:Animals
    89. Chernausek SD. Insulin-like growth factor-I (IGF-I) production by astroglial cells: regulation and importance for epidermal growth factor-induced cell replication. J Neurosci Res. 1993 Feb 01; 34(2):189-97. PMID: 8450562.
      Citations: 13     Fields:    Translation:AnimalsCells
    90. Smith EP, Cheung PT, Ferguson A, Chernausek SD. Mechanisms of Sertoli cell insulin-like growth factor (IGF)-binding protein-3 regulation by IGF-I and adenosine 3',5'-monophosphate. Endocrinology. 1992 Dec; 131(6):2733-41. PMID: 1280204.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    91. Iwamoto HS, Murray MA, Chernausek SD. Effects of acute hypoxemia on insulin-like growth factors and their binding proteins in fetal sheep. Am J Physiol. 1992 12; 263(6):E1151-6. PMID: 1282302.
      Citations: 4     Fields:    Translation:Animals
    92. Rosenfeld RG, Frane J, Attie KM, Brasel JA, Burstein S, Cara JF, Chernausek S, Gotlin RW, Kuntze J, Lippe BM, et al. Six-year results of a randomized, prospective trial of human growth hormone and oxandrolone in Turner syndrome. J Pediatr. 1992 Jul; 121(1):49-55. PMID: 1625092.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    93. Menon RK, Chernausek SD, Sperling MA. Ontogeny of insulin-like growth factor I and insulin receptor kinase activity in rat liver. J Dev Physiol. 1991 Aug; 16(2):87-97. PMID: 1664842.
      Citations:    Fields:    Translation:AnimalsCells
    94. Cheung PT, Smith EP, Shimasaki S, Ling N, Chernausek SD. Characterization of an insulin-like growth factor binding protein (IGFBP-4) produced by the B104 rat neuronal cell line: chemical and biological properties and differential synthesis by sublines. Endocrinology. 1991 Aug; 129(2):1006-15. PMID: 1713156.
      Citations: 10     Fields:    Translation:AnimalsCells
    95. Chernausek SD, Dickson BA, Smith EP, Hoath SB. Suppression of insulin-like growth factor I during epidermal growth factor-induced growth retardation. Am J Physiol. 1991 Mar; 260(3 Pt 1):E416-21. PMID: 2003595.
      Citations: 1     Fields:    Translation:Animals
    96. Smith EP, Dickson BA, Chernausek SD. Insulin-like growth factor binding protein-3 secretion from cultured rat sertoli cells: dual regulation by follicle stimulating hormone and insulin-like growth factor-I. Endocrinology. 1990 Dec; 127(6):2744-51. PMID: 1701126.
      Citations: 5     Fields:    Translation:AnimalsCells
    97. Bucuvalas JC, Cutfield W, Horn J, Sperling MA, Heubi JE, Campaigne B, Chernausek SD. Resistance to the growth-promoting and metabolic effects of growth hormone in children with chronic liver disease. J Pediatr. 1990 Sep; 117(3):397-402. PMID: 2391594.
      Citations: 12     Fields:    Translation:Humans
    98. Low L, Chernausek SD, Sperling MA. Acromegaloid patients with type A insulin resistance: parallel defects in insulin and insulin-like growth factor-I receptors and biological responses in cultured fibroblasts. J Clin Endocrinol Metab. 1989 Aug; 69(2):329-37. PMID: 2546962.
      Citations:    Fields:    Translation:HumansCells
    99. Hammond PB, Chernausek SD, Succop PA, Shukla R, Bornschein RL. Mechanisms by which lead depresses linear and ponderal growth in weanling rats. Toxicol Appl Pharmacol. 1989 Jul; 99(3):474-86. PMID: 2749734.
      Citations: 8     Fields:    Translation:Animals
    100. Chernausek SD, Turner R. Attenuation of spontaneous, nocturnal growth hormone secretion in children with hypothyroidism and its correlation with plasma insulin-like growth factor I concentrations. J Pediatr. 1989 Jun; 114(6):968-72. PMID: 2723911.
      Citations: 4     Fields:    Translation:Humans
    101. Orlowski CC, Chernausek SD, Akeson R. Actions of insulin-like growth factor-I on the B104 neuronal cell line: effects on cell replication, receptor characteristics, and influence of secreted binding protein on ligand binding. J Cell Physiol. 1989 Jun; 139(3):469-76. PMID: 2544609.
      Citations: 1     Fields:    Translation:AnimalsCells
    102. Mendenhall CL, Chernausek SD, Ray MB, Gartside PS, Roselle GA, Grossman CJ, Chedid A. The interactions of insulin-like growth factor I(IGF-I) with protein-calorie malnutrition in patients with alcoholic liver disease: V.A. Cooperative Study on Alcoholic Hepatitis VI. Alcohol Alcohol. 1989; 24(4):319-29. PMID: 2506872.
      Citations:    Fields:    Translation:Humans
    103. Rosenfeld RG, Hintz RL, Johanson AJ, Sherman B, Brasel JA, Burstein S, Chernausek S, Compton P, Frane J, Gotlin RW, et al. Three-year results of a randomized prospective trial of methionyl human growth hormone and oxandrolone in Turner syndrome. J Pediatr. 1988 Aug; 113(2):393-400. PMID: 3397807.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    104. Orlowski CC, Chernausek SD. Discordance of serum and tissue somatomedin levels in growth hormone-stimulated growth in the rat. Endocrinology. 1988 Jul; 123(1):44-9. PMID: 3383779.
      Citations: 7     Fields:    Translation:Animals
    105. Trippel SB, Chernausek SD, Van Wyk JJ, Moses AC, Mankin HJ. Demonstration of type I and type II somatomedin receptors on bovine growth plate chondrocytes. J Orthop Res. 1988; 6(6):817-26. PMID: 2971791.
      Citations: 3     Fields:    Translation:AnimalsCells
    106. Chernausek SD, Beach DC, Banach W, Sperling MA. Characteristics of hepatic receptors for somatomedin-C/insulin-like growth factor I and insulin in the developing human. J Clin Endocrinol Metab. 1987 Apr; 64(4):737-43. PMID: 2950128.
      Citations: 2     Fields:    Translation:Humans
    107. Rosenfeld RG, Hintz RL, Johanson AJ, Brasel JA, Burstein S, Chernausek SD, Clabots T, Frane J, Gotlin RW, Kuntze J, et al. Methionyl human growth hormone and oxandrolone in Turner syndrome: preliminary results of a prospective randomized trial. J Pediatr. 1986 Dec; 109(6):936-43. PMID: 3537249.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    108. Chernausek SD, Leslie ND, Bloch CA, Sperling MA. Endocrine disorders in children. Surg Clin North Am. 1985 Dec; 65(6):1527-49. PMID: 2866586.
      Citations:    Fields:    Translation:Humans
    109. Shaul PW, Towbin RB, Chernausek SD. Precocious puberty following severe head trauma. Am J Dis Child. 1985 May; 139(5):467-9. PMID: 3157313.
      Citations: 3     Fields:    Translation:Humans
    110. Chernausek SD, Chatelain PG, Svoboda ME, Underwood LE, Van Wyk JJ. Efficient purification of somatomedin-C/insulin-like growth factor I using immunoaffinity chromatography. Biochem Biophys Res Commun. 1985 Jan 16; 126(1):282-8. PMID: 3882085.
      Citations: 1     Fields:    Translation:Humans
    111. Chernausek SD, Underwood LE, Utiger RD, Van Wyk JJ. Growth hormone secretion and plasma somatomedin-C in primary hypothyroidism. Clin Endocrinol (Oxf). 1983 Sep; 19(3):337-44. PMID: 6354519.
      Citations: 10     Fields:    Translation:Humans
    112. Chernausek SD, Underwood LE, Van Wyk JJ. Influence of hypothyroidism on growth hormone binding by rat liver. Endocrinology. 1982 Nov; 111(5):1534-8. PMID: 6290187.
      Citations: 4     Fields:    Translation:AnimalsCells
    113. Chernausek SD, Jacobs S, Van Wyk JJ. Structural similarities between human receptors for somatomedin C and insulin: analysis by affinity labeling. Biochemistry. 1981 Dec 22; 20(26):7345-50. PMID: 6275879.
      Citations: 16     Fields:    Translation:HumansCells
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