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Timothy J Hubin

TitleProfessor
InstitutionSouthwestern Oklahoma State University
DepartmentChemistry and Physics
AddressCPP 201-A
100 Campus Drive
Weatherford OK 73096
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Renard I, D'huys T, Burke BP, Ajoleza T, Cain AN, Funwie NL, Khan A, Maples DL, Maples RD, Matz DL, McRobbie G, Ullom R, Prior TJ, Linder DP, Van Loy T, Hubin TJ, Schols D, Archibald SJ. Rigid Macrocycle Metal Complexes as CXCR4 Chemokine Receptor Antagonists: Influence of Ring Size. Pharmaceutics. 2024 Jul 28; 16(8). PMID: 39204345; PMCID: PMC11360128.
      Citations:    
    2. Alzahrani SO, McRobbie G, Khan A, D'huys T, Van Loy T, Walker AN, Renard I, Hubin TJ, Schols D, Burke BP, Archibald SJ. trans-IV restriction: a new configuration for metal bis-cyclam complexes as potent CXCR4 inhibitors. Dalton Trans. 2024 Mar 19; 53(12):5616-5623. PMID: 38439632; PMCID: PMC10949960.
      Citations: 1     Fields:    
    3. Hubin DJ, Cunningham BM, Hubin TJ, Ebel JP, Krause JA, Oliver AG. The unanti-cipated oxidation of a tertiary amine in a tetra-cyclic glyoxal-cyclam condensate yielding zinc(II) coordinated to a sterically hindered amine oxide. Acta Crystallogr E Crystallogr Commun. 2024 Mar 01; 80(Pt 4):343-346. PMID: 38584736; PMCID: PMC10993591.
      Citations:    
    4. Garcia L, Koper MR, Mondal S, Priddle JT, Truong WA, Allbritton EMA, McAdoo AG, Cannon-Smith DJ, Funwie NL, Hoang T, Kim I, Hubin DJ, Krause JA, Oliver AG, Prior TJ, Hubin TJ. Earth Abundant Oxidation Catalysts for Removal of Contaminants of Emerging Concern from Wastewater: Homogeneous Catalytic Screening of Monomeric Complexes. Molecules. 2023 Sep 06; 28(18). PMID: 37764242; PMCID: PMC10536317.
      Citations:    Fields:    
    5. Walker AN, Ayala MA, Mondal S, Bergagnini MC, Bui PJD, Chidester SN, Doeden CI, Esjornson L, Sweany BR, Garcia L, Krause JA, Oliver AG, Prior TJ, Hubin TJ. A Bridge too Far? Comparison of Transition Metal Complexes of Dibenzyltetraazamacrocycles with and without Ethylene Cross-Bridges: X-ray Crystal Structures, Kinetic Stability, and Electronic Properties. Molecules. 2023 Jan 16; 28(2). PMID: 36677952.
      Citations: 1     Fields:    
    6. Hoang T, Mondal S, Allen MB, Garcia L, Krause JA, Oliver AG, Prior TJ, Hubin TJ. Synthesis and Characterization of Late Transition Metal Complexes of Mono-Acetate Pendant Armed Ethylene Cross-Bridged Tetraazamacrocycles with Promise as Oxidation Catalysts for Dye Bleaching. Molecules. 2022 Dec 27; 28(1). PMID: 36615426.
      Citations: 2     Fields:    Translation:Cells
    7. Brewer SM, Schwartz TM, Mekhail MA, Turan LS, Prior TJ, Hubin TJ, Janesko BG, Green KN. Mechanistic Insights into Iron-Catalyzed C-H Bond Activation and C-C Coupling. Organometallics. 2021 Aug 09; 40(15):2467-2477. PMID: 36210909; PMCID: PMC9542290.
      Citations: 3     
    8. Shircliff AD, Burke BP, Davilla DJ, Burgess GE, Okorocha FA, Shrestha A, Allbritton EMA, Nguyen PT, Lamar RL, Jones DG, Gorbet MJ, Allen MB, Eze JI, Fernandez AT, Ramirez D, Archibald SJ, Prior TJ, Krause JA, Oliver AG, Hubin TJ. An ethylene cross-bridged pentaazamacrocycle and its Cu2+ complex: constrained ligand topology and excellent kinetic stability. Chem Commun (Camb). 2020 Jul 11; 56(54):7519-7522. PMID: 32510060.
      Citations: 2     Fields:    
    9. Burke BP, Miranda CS, Lee RE, Renard I, Nigam S, Clemente GS, D'Huys T, Ruest T, Domarkas J, Thompson JA, Hubin TJ, Schols D, Cawthorne CJ, Archibald SJ. 64Cu PET Imaging of the CXCR4 Chemokine Receptor Using a Cross-Bridged Cyclam Bis-Tetraazamacrocyclic Antagonist. J Nucl Med. 2020 01; 61(1):123-128. PMID: 31201250.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    10. Hubin TJ, Walker AN, Davilla DJ, Freeman TNC, Epley BM, Hasley TR, Amoyaw PNA, Jain S, Archibald SJ, Prior TJ, Krause JA, Oliver AG, Tekwani BL, Khan MOF. Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads. Polyhedron. 2019 May 01; 163:42-53. PMID: 30976133.
      Citations: 6     
    11. Cain AN, Carder Freeman TN, Roewe KD, Cockriel DL, Hasley TR, Maples RD, Allbritton EMA, D'Huys T, van Loy T, Burke BP, Prior TJ, Schols D, Archibald SJ, Hubin TJ. Acetate as a model for aspartate-based CXCR4 chemokine receptor binding of cobalt and nickel complexes of cross-bridged tetraazamacrocycles. Dalton Trans. 2019 Feb 19; 48(8):2785-2801. PMID: 30729243.
      Citations: 4     Fields:    
    12. Brewer SM, Wilson KR, Jones DG, Reinheimer EW, Archibald SJ, Prior TJ, Ayala MA, Foster AL, Hubin TJ, Green KN. Increase of Direct C-C Coupling Reaction Yield by Identifying Structural and Electronic Properties of High-Spin Iron Tetra-azamacrocyclic Complexes. Inorg Chem. 2018 Aug 06; 57(15):8890-8902. PMID: 30024738.
      Citations: 10     Fields:    
    13. Khan MO, Keiser J, Amoyaw PN, Hossain MF, Vargas M, Le JG, Simpson NC, Roewe KD, Freeman TN, Hasley TR, Maples RD, Archibald SJ, Hubin TJ. Discovery of Antischistosomal Drug Leads Based on Tetraazamacrocyclic Derivatives and Their Metal Complexes. Antimicrob Agents Chemother. 2016 09; 60(9):5331-6. PMID: 27324765.
      Citations: 12     Fields:    Translation:Animals
    14. Wilson KR, Cannon-Smith DJ, Burke BP, Birdsong OC, Archibald SJ, Hubin TJ. Synthesis and structural studies of two pyridine-armed reinforced cyclen chelators and their transition metal complexes. Polyhedron. 2016 Aug 16; 114:118-127. PMID: 27346907.
      Citations: 5     
    15. Maples RD, Cain AN, Burke BP, Silversides JD, Mewis RE, D'huys T, Schols D, Linder DP, Archibald SJ, Hubin TJ. Aspartate-Based CXCR4 Chemokine Receptor Binding of Cross-Bridged Tetraazamacrocyclic Copper(II) and Zinc(II) Complexes. Chemistry. 2016 Aug 26; 22(36):12916-30. PMID: 27458983.
      Citations: 10     Fields:    Translation:Cells
    16. Shircliff AD, Wilson KR, Cannon DJ, Jones DG, Zhang Z, Chen Z, Yin G, Prior TJ, Hubin TJ. Synthesis, structural studies, and oxidation catalysis of the manganese(II), iron(II), and copper(II) complexes of a 2-pyridylmethyl pendant armed side-bridged cyclam. Inorg Chem Commun. 2015 Sep 01; 59:71-75. PMID: 26273213.
      Citations: 7     
    17. Funwie NL, Cain AN, Fanning BZ, Hageman SA, Mullens M, Roberts TK, Turner DJ, Valdez CN, Vaughan RW, Ermias HG, Silversides JD, Archibald SJ, Hubin TJ, Prior TJ. Crystal structure of di-chlorido-(4,11-dimethyl-1,4,8,11-tetra-aza-bicyclo-[6.6.2]hexa-deca-ne)iron(III) hexa-fluorido-phosphate. Acta Crystallogr E Crystallogr Commun. 2015 Sep 01; 71(Pt 9):1073-6. PMID: 26396852.
      Citations: 1     
    18. Matz DL, Jones DG, Roewe KD, Gorbet MJ, Zhang Z, Chen Z, Prior TJ, Archibald SJ, Yin G, Hubin TJ. Synthesis, structural studies, kinetic stability, and oxidation catalysis of the late first row transition metal complexes of 4,10-dimethyl-1,4,7,10-tetraazabicyclo[6.5.2]pentadecane. Dalton Trans. 2015 Jul 21; 44(27):12210-24. PMID: 25876140.
      Citations: 8     Fields:    Translation:Cells
    19. Panneerselvam J, Jin J, Shanker M, Lauderdale J, Bates J, Wang Q, Zhao YD, Archibald SJ, Hubin TJ, Ramesh R. IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis. PLoS One. 2015; 10(3):e0122439. PMID: 25775124.
      Citations: 36     Fields:    Translation:HumansCells
    20. Jones DG, Wilson KR, Cannon-Smith DJ, Shircliff AD, Zhang Z, Chen Z, Prior TJ, Yin G, Hubin TJ. Synthesis, structural studies, and oxidation catalysis of the late-first-row-transition-metal complexes of a 2-pyridylmethyl pendant-armed ethylene cross-bridged cyclam. Inorg Chem. 2015 Mar 02; 54(5):2221-34. PMID: 25671291.
      Citations: 13     Fields:    Translation:Cells
    21. Zhang Z, Coats KL, Chen Z, Hubin TJ, Yin G. Influence of calcium(II) and chloride on the oxidative reactivity of a manganese(II) complex of a cross-bridged cyclen ligand. Inorg Chem. 2014 Nov 17; 53(22):11937-47. PMID: 25375413.
      Citations: 6     Fields:    
    22. Rudraraju AV, Amoyaw PN, Hubin TJ, Khan MO. Determination of log P values of new cyclen based antimalarial drug leads using RP-HPLC. Pharmazie. 2014 Sep; 69(9):655-62. PMID: 25272935.
      Citations: 6     Fields:    
    23. Prior TJ, Maples DL, Maples RD, Hoffert WA, Parsell TH, Silversides JD, Archibald SJ, Hubin TJ. Crystal structures of two cross-bridged chromium(III) tetra-aza-macrocycles. Acta Crystallogr Sect E Struct Rep Online. 2014 Sep 01; 70(Pt 9):148-52. PMID: 25309165.
      Citations:    
    24. Hubin TJ, Amoyaw PN, Roewe KD, Simpson NC, Maples RD, Carder Freeman TN, Cain AN, Le JG, Archibald SJ, Khan SI, Tekwani BL, Khan MO. Synthesis and antimalarial activity of metal complexes of cross-bridged tetraazamacrocyclic ligands. Bioorg Med Chem. 2014 Jul 01; 22(13):3239-44. PMID: 24857776.
      Citations: 14     Fields:    Translation:AnimalsCells
    25. Smith R, Huskens D, Daelemans D, Mewis RE, Garcia CD, Cain AN, Freeman TN, Pannecouque C, De Clercq E, Schols D, Hubin TJ, Archibald SJ. CXCR4 chemokine receptor antagonists: nickel(II) complexes of configurationally restricted macrocycles. Dalton Trans. 2012 Oct 07; 41(37):11369-77. PMID: 22892890.
      Citations: 12     Fields:    Translation:HumansCells
    26. Maples DL, Maples RD, Hoffert WA, Parsell TH, van Asselt A, Silversides JD, Archibald SJ, Hubin TJ. Synthesis and Characterization of the Chromium(III) complexes of Ethylene Cross-Bridged Cyclam and Cyclen Ligands. Inorganica Chim Acta. 2009 Apr 20; 362(6):2084-2088. PMID: 20161052.
      Citations: 1     
    27. Khan A, Nicholson G, Greenman J, Madden L, McRobbie G, Pannecouque C, De Clercq E, Ullom R, Maples DL, Maples RD, Silversides JD, Hubin TJ, Archibald SJ. Binding optimization through coordination chemistry: CXCR4 chemokine receptor antagonists from ultrarigid metal complexes. J Am Chem Soc. 2009 Mar 18; 131(10):3416-7. PMID: 19231846.
      Citations: 23     Fields:    Translation:Cells
    28. McClain JM, Maples DL, Maples RD, Matz DL, Harris SM, Nelson AD, Silversides JD, Archibald SJ, Hubin TJ. Dichloro(4,10-dimethyl-1,4,7,10-tetraazabicyclo[5.5.2]tetradecane)iron(III) hexafluorophosphate. Acta Crystallogr C. 2006 Nov; 62(Pt 11):m553-5. PMID: 17088625.
      Citations: 4     Fields:    
    29. Valks GC, McRobbie G, Lewis EA, Hubin TJ, Hunter TM, Sadler PJ, Pannecouque C, De Clercq E, Archibald SJ. Configurationally restricted bismacrocyclic CXCR4 receptor antagonists. J Med Chem. 2006 Oct 19; 49(21):6162-5. PMID: 17034122.
      Citations: 19     Fields:    Translation:HumansCells
    30. May CM, Archibald SJ, Bridgeman AJ, Empson CJ, Hubin TJ. Rigidity extremes in coordination chemistry: a fine energetic balance in the isolation of a trapped ligand inversion intermediate. Chem Commun (Camb). 2004 Aug 21; (16):1880-1. PMID: 15306930.
      Citations:    Fields:    
    31. Hubin TJ, Alcock NW, Seib LL, Busch DH. Synthesis and X-ray crystal structure determination of the first Copper(II) complexes of tetraazamacrocycle-glyoxal condensates. Inorg Chem. 2002 Dec 30; 41(26):7006-14. PMID: 12495338.
      Citations:    Fields:    
    32. Hubin TJ, Tyryshkin N, Alcock NW, Busch DH. Trans-dioxocyclam (1,4,8,11-tetraazacyclotetradecane-2,9-dione) dihydrate and its NiII complex. Acta Crystallogr C. 2001 Apr; 57(Pt 4):359-62. PMID: 11313558.
      Citations:    Fields:    
    33. Hubin TJ, McCormick JM, Alcock NW, Busch DH. Topologically constrained manganese(III) and iron(III) complexes of two cross-bridged tetraazamacrocycles. Inorg Chem. 2001 Jan 29; 40(3):435-44. PMID: 11209599.
      Citations: 16     Fields:    
    34. Hubin TJ, McCormick JM, Alcock NW, Clase HJ, Busch DH. Crystallographic Characterization of Stepwise Changes in Ligand Conformations as Their Internal Topology Changes and Two Novel Cross-Bridged Tetraazamacrocyclic Copper(II) Complexes. Inorg Chem. 1999 Oct 04; 38(20):4435-4446. PMID: 11671154.
      Citations: 13     Fields:    
    35. Hubin TJ, McCormick JM, Alcock NW, Busch DH. Synthesis and X-ray Crystal Structure Determination of the First Transition Metal Complexes of the Tetracycles Formed by Tetraazamacrocycle-Glyoxal Condensation: PdLCl(2) (L = Cyclam-Glyoxal Condensate (1), Cyclen-Glyoxal Condensate (2)). Inorg Chem. 1998 Dec 14; 37(25):6549-6551. PMID: 11670781.
      Citations: 1     Fields:    
    36. Goldstein SR, Hubin T, Rosenthal S, Washburn C. A confocal video-rate laser-beam scanning reflected-light microscope with no moving parts. J Microsc. 1990 Jan; 157(Pt 1):29-38. PMID: 2299661.
      Citations: 3     Fields:    Translation:Animals
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