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Vassilios I Sikavitsas

InstitutionUniversity of Oklahoma, Norman
DepartmentBiomedical Engineering
202 W. Boyd St
Norman OK 73019
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Raguraman R, Bhavsar D, Kim D, Ren X, Sikavitsas V, Munshi A, Ramesh R. Tumor-targeted exosomes for delivery of anticancer drugs. Cancer Lett. 2023 04 01; 558:216093. PMID: 36822543; PMCID: PMC10025995.
      Citations:    Fields:    Translation:HumansCells
    2. Karami D, Srivastava A, Ramesh R, Sikavitsas VI. Investigating Cancerous Exosomes' Effects on CD8+ T-Cell IL-2 Production in a 3D Unidirectional Flow Bioreactor Using 3D Printed, RGD-Functionalized PLLA Scaffolds. J Funct Biomater. 2022 Mar 11; 13(1). PMID: 35323230.
    3. Richbourg NR, Peppas NA, Sikavitsas VI. Tuning the biomimetic behavior of scaffolds for regenerative medicine through surface modifications. J Tissue Eng Regen Med. 2019 08; 13(8):1275-1293. PMID: 30946537.
      Citations: 36     Fields:    
    4. Karami D, Richbourg N, Sikavitsas V. Dynamic in vitro models for tumor tissue engineering. Cancer Lett. 2019 05 01; 449:178-185. PMID: 30763717.
      Citations: 5     Fields:    Translation:Humans
    5. Kadri OE, Williams C, Sikavitsas V, Voronov RS. Numerical accuracy comparison of two boundary conditions commonly used to approximate shear stress distributions in tissue engineering scaffolds cultured under flow perfusion. Int J Numer Method Biomed Eng. 2018 11; 34(11):e3132. PMID: 30047248.
      Citations: 2     Fields:    Translation:Humans
    6. Simmons AD, Sikavitsas VI. Monitoring Bone Tissue Engineered (BTE) Constructs Based on the Shifting Metabolism of Differentiating Stem Cells. Ann Biomed Eng. 2018 Jan; 46(1):37-47. PMID: 29022110.
      Citations:    Fields:    Translation:AnimalsCells
    7. Engebretson B, Mussett ZR, Sikavitsas VI. The effects of varying frequency and duration of mechanical stimulation on a tissue-engineered tendon construct. Connect Tissue Res. 2018 03; 59(2):167-177. PMID: 28459287.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    8. Krais JJ, Virani N, McKernan PH, Nguyen Q, Fung KM, Sikavitsas VI, Kurkjian C, Harrison RG. Antitumor Synergism and Enhanced Survival with a Tumor Vasculature-Targeted Enzyme Prodrug System, Rapamycin, and Cyclophosphamide. Mol Cancer Ther. 2017 09; 16(9):1855-1865. PMID: 28522586.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    9. Trachtenberg JE, Santoro M, Williams C, Piard CM, Smith BT, Placone JK, Menegaz BA, Molina ER, Lamhamedi-Cherradi SE, Ludwig JA, Sikavitsas VI, Fisher JP, Mikos AG. Effects of Shear Stress Gradients on Ewing Sarcoma Cells Using 3D Printed Scaffolds and Flow Perfusion. ACS Biomater Sci Eng. 2018 Feb 12; 4(2):347-356. PMID: 33418729.
      Citations: 5     Fields:    
    10. Engebretson B, Mussett ZR, Sikavitsas VI. Tenocytic extract and mechanical stimulation in a tissue-engineered tendon construct increases cellular proliferation and ECM deposition. Biotechnol J. 2017 Mar; 12(3). PMID: 28008725.
      Citations: 4     Fields:    Translation:HumansCells
    11. Simmons AD, Williams C, Degoix A, Sikavitsas VI. Sensing metabolites for the monitoring of tissue engineered construct cellularity in perfusion bioreactors. Biosens Bioelectron. 2017 Apr 15; 90:443-449. PMID: 27825527.
      Citations: 7     Fields:    Translation:AnimalsCells
    12. Van Rite BD, Krais JJ, Cherry M, Sikavitsas VI, Kurkjian C, Harrison RG. Antitumor activity of an enzyme prodrug therapy targeted to the breast tumor vasculature. Cancer Invest. 2013 Oct; 31(8):505-10. PMID: 24083814.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    13. Landy BC, Vangordon SB, McFetridge PS, Sikavitsas VI, Jarman-Smith M. Mechanical and in vitro investigation of a porous PEEK foam for medical device implants. J Appl Biomater Funct Mater. 2013 Jun 24; 11(1):e35-44. PMID: 23413130.
      Citations: 10     Fields:    Translation:AnimalsCells
    14. Voronov RS, VanGordon SB, Shambaugh RL, Papavassiliou DV, Sikavitsas VI. 3D tissue-engineered construct analysis via conventional high-resolution microcomputed tomography without X-ray contrast. Tissue Eng Part C Methods. 2013 May; 19(5):327-35. PMID: 23020551.
      Citations: 3     Fields:    Translation:AnimalsCells
    15. Shi L, Brunski DB, Sikavitsas VI, Johnson MB, Striolo A. Friction coefficients for mechanically damaged bovine articular cartilage. Biotechnol Bioeng. 2012 Jul; 109(7):1769-78. PMID: 22252687.
      Citations: 2     Fields:    Translation:Animals
    16. Pham NH, Voronov RS, Vangordon SB, Sikavitsas VI, Papavassiliou DV. Predicting the stress distribution within scaffolds with ordered architecture. Biorheology. 2012; 49(4):235-47. PMID: 22836078.
      Citations: 2     Fields:    
    17. Engebretson B, Sikavitsas VI. Long-term in vivo effect of PEG bone tissue engineering scaffolds. J Long Term Eff Med Implants. 2012; 22(3):211-8. PMID: 23582112.
      Citations: 8     Fields:    Translation:Humans
    18. Issa RI, Engebretson B, Rustom L, McFetridge PS, Sikavitsas VI. The effect of cell seeding density on the cellular and mechanical properties of a mechanostimulated tissue-engineered tendon. Tissue Eng Part A. 2011 Jun; 17(11-12):1479-87. PMID: 21275843.
      Citations: 12     Fields:    Translation:HumansCells
    19. Alvarez-Barreto JF, Landy B, VanGordon S, Place L, DeAngelis PL, Sikavitsas VI. Enhanced osteoblastic differentiation of mesenchymal stem cells seeded in RGD-functionalized PLLA scaffolds and cultured in a flow perfusion bioreactor. J Tissue Eng Regen Med. 2011 Jun; 5(6):464-75. PMID: 20878644.
      Citations: 10     Fields:    Translation:AnimalsCells
    20. Shi L, Sikavitsas VI, Striolo A. Experimental friction coefficients for bovine cartilage measured with a pin-on-disk tribometer: testing configuration and lubricant effects. Ann Biomed Eng. 2011 Jan; 39(1):132-46. PMID: 20872073.
      Citations: 10     Fields:    Translation:Animals
    21. Voronov R, Vangordon S, Sikavitsas VI, Papavassiliou DV. Computational modeling of flow-induced shear stresses within 3D salt-leached porous scaffolds imaged via micro-CT. J Biomech. 2010 May 07; 43(7):1279-86. PMID: 20185132.
      Citations: 14     Fields:    
    22. Abousleiman RI, Reyes Y, McFetridge P, Sikavitsas V. Tendon tissue engineering using cell-seeded umbilical veins cultured in a mechanical stimulator. Tissue Eng Part A. 2009 Apr; 15(4):787-95. PMID: 18991488.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    23. Abousleiman RI, Reyes Y, McFetridge P, Sikavitsas V. The human umbilical vein: a novel scaffold for musculoskeletal soft tissue regeneration. Artif Organs. 2008 Sep; 32(9):735-42. PMID: 18684203.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    24. Castano-Izquierdo H, Alvarez-Barreto J, van den Dolder J, Jansen JA, Mikos AG, Sikavitsas VI. Pre-culture period of mesenchymal stem cells in osteogenic media influences their in vivo bone forming potential. J Biomed Mater Res A. 2007 Jul; 82(1):129-38. PMID: 17269144.
      Citations: 46     Fields:    Translation:AnimalsCells
    25. Alvarez-Barreto JF, Shreve MC, Deangelis PL, Sikavitsas VI. Preparation of a functionally flexible, three-dimensional, biomimetic poly(L-lactic acid) scaffold with improved cell adhesion. Tissue Eng. 2007 Jun; 13(6):1205-17. PMID: 17518730.
      Citations: 3     Fields:    Translation:AnimalsCells
    26. Alvarez-Barreto JF, Sikavitsas VI. Improved mesenchymal stem cell seeding on RGD-modified poly(L-lactic acid) scaffolds using flow perfusion. Macromol Biosci. 2007 May 10; 7(5):579-88. PMID: 17457938.
      Citations: 15     Fields:    Translation:AnimalsCells
    27. Alvarez-Barreto JF, Linehan SM, Shambaugh RL, Sikavitsas VI. Flow perfusion improves seeding of tissue engineering scaffolds with different architectures. Ann Biomed Eng. 2007 Mar; 35(3):429-42. PMID: 17216348.
      Citations: 30     Fields:    Translation:AnimalsCells
    28. Datta N, Pham QP, Sharma U, Sikavitsas VI, Jansen JA, Mikos AG. In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2488-93. PMID: 16477044.
      Citations: 115     Fields:    Translation:AnimalsCells
    29. Abousleiman RI, Sikavitsas VI. Bioreactors for tissues of the musculoskeletal system. Adv Exp Med Biol. 2006; 585:243-59. PMID: 17120789.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    30. Datta N, Holtorf HL, Sikavitsas VI, Jansen JA, Mikos AG. Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. Biomaterials. 2005 Mar; 26(9):971-7. PMID: 15369685.
      Citations: 90     Fields:    Translation:AnimalsCells
    31. Sikavitsas VI, Bancroft GN, Lemoine JJ, Liebschner MA, Dauner M, Mikos AG. Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds. Ann Biomed Eng. 2005 Jan; 33(1):63-70. PMID: 15709706.
      Citations: 38     Fields:    Translation:AnimalsCells
    32. Castano H, O'Rear EA, McFetridge PS, Sikavitsas VI. Polypyrrole thin films formed by admicellar polymerization support the osteogenic differentiation of mesenchymal stem cells. Macromol Biosci. 2004 Aug 09; 4(8):785-94. PMID: 15468272.
      Citations: 16     Fields:    Translation:AnimalsCells
    33. Sikavitsas VI, van den Dolder J, Bancroft GN, Jansen JA, Mikos AG. Influence of the in vitro culture period on the in vivo performance of cell/titanium bone tissue-engineered constructs using a rat cranial critical size defect model. J Biomed Mater Res A. 2003 Dec 01; 67(3):944-51. PMID: 14613243.
      Citations: 26     Fields:    Translation:AnimalsCells
    34. Sikavitsas VI, Bancroft GN, Holtorf HL, Jansen JA, Mikos AG. Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):14683-8. PMID: 14657343.
      Citations: 121     Fields:    Translation:AnimalsCells
    35. Behravesh E, Sikavitsas VI, Mikos AG. Quantification of ligand surface concentration of bulk-modified biomimetic hydrogels. Biomaterials. 2003 Nov; 24(24):4365-74. PMID: 12922149.
      Citations: 12     Fields:    
    36. Gomes ME, Sikavitsas VI, Behravesh E, Reis RL, Mikos AG. Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds. J Biomed Mater Res A. 2003 Oct 01; 67(1):87-95. PMID: 14517865.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    37. van den Dolder J, Bancroft GN, Sikavitsas VI, Spauwen PH, Mikos AG, Jansen JA. Effect of fibronectin- and collagen I-coated titanium fiber mesh on proliferation and differentiation of osteogenic cells. Tissue Eng. 2003 Jun; 9(3):505-15. PMID: 12857418.
      Citations: 13     Fields:    Translation:AnimalsCells
    38. Bancroft GN, Sikavitsas VI, Mikos AG. Design of a flow perfusion bioreactor system for bone tissue-engineering applications. Tissue Eng. 2003 Jun; 9(3):549-54. PMID: 12857422.
      Citations: 75     Fields:    Translation:Animals
    39. van den Dolder J, Bancroft GN, Sikavitsas VI, Spauwen PH, Jansen JA, Mikos AG. Flow perfusion culture of marrow stromal osteoblasts in titanium fiber mesh. J Biomed Mater Res A. 2003 Feb 01; 64(2):235-41. PMID: 12522809.
      Citations: 23     Fields:    Translation:AnimalsCells
    40. Sikavitsas VI, Bancroft GN, Mikos AG. Formation of three-dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor. J Biomed Mater Res. 2002 Oct; 62(1):136-48. PMID: 12124795.
      Citations: 68     Fields:    Translation:AnimalsCells
    41. Bancroft GN, Sikavitsas VI, van den Dolder J, Sheffield TL, Ambrose CG, Jansen JA, Mikos AG. Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):12600-5. PMID: 12242339.
      Citations: 138     Fields:    Translation:AnimalsCells
    42. Sikavitsas V, Nitsche JM, Mountziaris TJ. Transport and kinetic processes underlying biomolecular interactions in the BIACORE optical biosensor. Biotechnol Prog. 2002 Jul-Aug; 18(4):885-97. PMID: 12153326.
      Citations: 5     Fields:    Translation:Cells
    43. Sikavitsas VI, Temenoff JS, Mikos AG. Biomaterials and bone mechanotransduction. Biomaterials. 2001 Oct; 22(19):2581-93. PMID: 11519777.
      Citations: 71     Fields:    Translation:Humans
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