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William Orr

TitleAsoc
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentMedicine Gastroenterology
AddressWP 1345
920 Stanton L Young Blvd
Oklahoma City OK 73104
Phone405/271-5428
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lei WY, Liang SW, Hung JS, Wong MW, Liu TT, Yi CH, Lin L, Orr WC, Chen CL. Effects of menthol on esophageal motility in humans: Studies using high-resolution manometry. Neurogastroenterol Motil. 2021 Sep 14; e14267. PMID: 34520608.
      Citations:    Fields:    
    2. Chen CL, Wong MW, Hung JS, Liang SW, Liu TT, Yi CH, Lin L, Orr WC, Lei WY. Effects of codeine on esophageal peristalsis in humans using high resolution manometry. J Gastroenterol Hepatol. 2021 Jul 28. PMID: 34322907.
      Citations:    Fields:    
    3. Wong MW, Hung JS, Liu TT, Yi CH, Lei WY, Liang SW, Orr WC, Chen CL. Esophageal acid burden in reflux patients with normal endoscopy: Does esophageal peristalsis matter? J Formos Med Assoc. 2021 Jun 02. PMID: 34090788.
      Citations:    Fields:    
    4. Wong MW, Liu TT, Yi CH, Hung JS, Lei WY, Liang SW, Orr WC, Chen CL. Effect of prucalopride on sildenafil-induced inhibition of esophageal peristalsis in healthy adults. J Gastroenterol Hepatol. 2021 Jun; 36(6):1556-1561. PMID: 33080085.
      Citations:    Fields:    Translation:Humans
    5. Orr WC, Fass R, Sundaram SS, Scheimann AO. The effect of sleep on gastrointestinal functioning in common digestive diseases. Lancet Gastroenterol Hepatol. 2020 06; 5(6):616-624. PMID: 32416862.
      Citations: 3     Fields:    Translation:Humans
    6. Raad S, Wilkerson M, Jones KR, Orr WC. The effect of baclofen on objective and subjective sleep measures in a model of transient insomnia. Sleep Med. 2020 08; 72:130-134. PMID: 32615462.
      Citations:    Fields:    Translation:Humans
    7. Lei WY, Wang JH, Yi CH, Liu TT, Hung JS, Wong MW, Bair MJ, Vaezi MF, Orr WC, Chen CL. Association between use of proton pump inhibitors and colorectal cancer: A nationwide population-based study. Clin Res Hepatol Gastroenterol. 2021 Jan; 45(1):101397. PMID: 32224118.
      Citations: 3     Fields:    
    8. Lei WY, Chang WC, Wen SH, Wong MW, Hung JS, Yi CH, Liu TT, Hsu CS, Orr WC, Vaezi MF, Pace F, Hsieh TC, Chen CL. Impact of concomitant dyspepsia and irritable bowel syndrome on symptom burden in patients with gastroesophageal reflux disease. J Formos Med Assoc. 2019 Apr; 118(4):797-806. PMID: 30584006.
      Citations: 2     Fields:    Translation:Humans
    9. Orr WC. Larks and owls and disease manifestation. Sleep Med. 2018 12; 52:196-197. PMID: 30318449.
      Citations:    Fields:    Translation:HumansAnimals
    10. Lei WY, Wang JH, Wen SH, Yi CH, Hung JS, Liu TT, Orr WC, Chen CL. Risk of acute myocardial infarction in patients with gastroesophageal reflux disease: A nationwide population-based study. PLoS One. 2017; 12(3):e0173899. PMID: 28319162.
      Citations: 4     Fields:    Translation:Humans
    11. Yi CH, Lei WY, Hung JS, Liu TT, Orr WC, Chen CL. Sleep disturbance and enhanced esophageal capsaicin sensitivity in patients with gastroesophageal reflux disease. J Gastroenterol Hepatol. 2016 Dec; 31(12):1940-1945. PMID: 27131333.
      Citations:    Fields:    Translation:Humans
    12. Yi CH, Lei WY, Hung JS, Liu TT, Orr WC, Chen CL. Relevance of sleep disturbance to the integrity and characteristics of secondary peristalsis in patients with gastroesophageal reflux disease. Scand J Gastroenterol. 2017 Feb; 52(2):136-142. PMID: 27608729.
      Citations:    Fields:    Translation:Humans
    13. Yi CH, Lei WY, Hung JS, Liu TT, Orr WC, Fabio P, Chen CL. Differences in the Control of Secondary Peristalsis in the Human Esophagus: Influence of the 5-HT4 Receptor versus the TRPV1 Receptor. PLoS One. 2016; 11(7):e0159452. PMID: 27438088.
      Citations:    Fields:    Translation:HumansAnimals
    14. Liu TT, Yi CH, Lei WY, Hung JS, Chen CL, Orr WC. Effects of esophageal capsaicin instillation on acid induced excitation of secondary peristalsis in humans. J Gastroenterol Hepatol. 2016 Feb; 31(2):364-9. PMID: 26250995.
      Citations:    Fields:    Translation:HumansCells
    15. Shepherd K, Orr W. Mechanism of Gastroesophageal Reflux in Obstructive Sleep Apnea: Airway Obstruction or Obesity? J Clin Sleep Med. 2016 Jan; 12(1):87-94. PMID: 26446244.
      Citations: 3     Fields:    Translation:Humans
    16. Hsu CS, Liu TT, Wen SH, Wang CC, Yi CH, Chen JH, Lei WY, Orr WC, Fabio P, Chen CL. Clinical, metabolic, and psychological characteristics in patients with gastroesophageal reflux disease overlap with irritable bowel syndrome. Eur J Gastroenterol Hepatol. 2015 May; 27(5):516-22. PMID: 25822860.
      Citations: 5     Fields:    Translation:Humans
    17. Glidewell RN, McPherson Botts E, Orr WC. Insomnia and Anxiety: Diagnostic and Management Implications of Complex Interactions. Sleep Med Clin. 2015 Mar; 10(1):93-9. PMID: 26055677.
      Citations: 5     Fields:    Translation:Humans
    18. Ali T, Orr WC. Sleep disturbances and inflammatory bowel disease. Inflamm Bowel Dis. 2014 Nov; 20(11):1986-95. PMID: 25025716.
      Citations: 13     Fields:    Translation:Humans
    19. Glidewell RN, Renn BN, Roby E, Orr WC. Predictors and patterns of insomnia symptoms in OSA before and after PAP therapy. Sleep Med. 2014 Aug; 15(8):899-905. PMID: 25011662.
      Citations: 16     Fields:    Translation:Humans
    20. López-Alvarenga JC, Orr W, Vargas-Romero JA, Remes-Troche JM, Morales-Arámbula M, Soto-Pérez JC, Mateos-Pérez G, Sobrino-Cossío S, Teramoto-Matsubara O, López-Colombo A, Orozco-Gamiz A, Saez-Ríos A, Arellano-Plancarte A, Chiu-Ugalde J, Tholen A, Horbach S, Lundberg L, Fass R. Relief of Night-time Symptoms Associated With Gastroesophageal Reflux Disease Following 4 Weeks of Treatment With Pantoprazole Magnesium: The Mexican Gastroesophageal Reflux Disease Working Group. J Neurogastroenterol Motil. 2014 Jan; 20(1):64-73. PMID: 24466446.
      Citations:    
    21. Ali T, Choe J, Awab A, Wagener TL, Orr WC. Sleep, immunity and inflammation in gastrointestinal disorders. World J Gastroenterol. 2013 Dec 28; 19(48):9231-9. PMID: 24409051.
      Citations: 35     Fields:    Translation:HumansAnimals
    22. Chen CL, Yi CH, Liu TT, Orr WC. Effects of mosapride on secondary peristalsis in patients with ineffective esophageal motility. Scand J Gastroenterol. 2013 Dec; 48(12):1363-70. PMID: 24099237.
      Citations: 7     Fields:    Translation:Humans
    23. Ali T, Madhoun MF, Orr WC, Rubin DT. Assessment of the relationship between quality of sleep and disease activity in inflammatory bowel disease patients. Inflamm Bowel Dis. 2013 Oct; 19(11):2440-3. PMID: 23945186.
      Citations: 41     Fields:    Translation:Humans
    24. Choung RS, Locke GR, Francis DD, Katzka D, Winkle PJ, Orr WC, Crowell MD, Devault K, Harmsen WS, Zinsmeister AR, Talley NJ. Novel partial 5HT3 agonist pumosetrag reduces acid reflux events in uninvestigated GERD patients after a standard refluxogenic meal: a randomized, double-blind, placebo-controlled pharmacodynamic study. Neurogastroenterol Motil. 2014 Jan; 26(1):13-20. PMID: 24001105.
      Citations: 3     Fields:    Translation:Humans
    25. Orr WC, Goodrich S, Estep ME, Shepherd K. The relationship between complaints of night-time heartburn and sleep-related gastroesophageal reflux. Dis Esophagus. 2014 May-Jun; 27(4):303-10. PMID: 24033500.
      Citations:    Fields:    Translation:Humans
    26. Orr WC, Goodrich S, Wright S, Shepherd K, Mellow M. The effect of baclofen on nocturnal gastroesophageal reflux and measures of sleep quality: a randomized, cross-over trial. Neurogastroenterol Motil. 2012 Jun; 24(6):553-9, e253. PMID: 22404184.
      Citations: 10     Fields:    Translation:Humans
    27. Glidewell RN, Roby EK, Orr WC. Is insomnia an independent predictor of obstructive sleep apnea? J Am Board Fam Med. 2012 Jan-Feb; 25(1):104-10. PMID: 22218631.
      Citations: 8     Fields:    Translation:Humans
    28. Chen CL, Liu TT, Yi CH, Orr WC. Evidence for altered anorectal function in irritable bowel syndrome patients with sleep disturbance. Digestion. 2011; 84(3):247-51. PMID: 21952561.
      Citations: 6     Fields:    Translation:Humans
    29. Liu TT, Yi CH, Chen CL, Orr WC. Impact of sleep dysfunction on anorectal motility in healthy humans. J Neurogastroenterol Motil. 2011 Apr; 17(2):180-4. PMID: 21602996.
      Citations:    
    30. Chen CL, Liu TT, Yi CH, Orr WC. Effects of mosapride on esophageal secondary peristalsis in humans. Neurogastroenterol Motil. 2011 Jul; 23(7):606-e249. PMID: 21501334.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    31. Mold JW, Quattlebaum C, Schinnerer E, Boeckman L, Orr W, Hollabaugh K. Identification by primary care clinicians of patients with obstructive sleep apnea: a practice-based research network (PBRN) study. J Am Board Fam Med. 2011 Mar-Apr; 24(2):138-45. PMID: 21383212.
      Citations: 17     Fields:    Translation:Humans
    32. Fass R, Johnson DA, Orr WC, Han C, Mody R, Stern KN, Pilmer BL, Perez MC. The effect of dexlansoprazole MR on nocturnal heartburn and GERD-related sleep disturbances in patients with symptomatic GERD. Am J Gastroenterol. 2011 Mar; 106(3):421-31. PMID: 21224838.
      Citations: 19     Fields:    Translation:Humans
    33. Orr WC. Alterations in gastrointestinal functioning during sleep. Handb Clin Neurol. 2011; 98:347-54. PMID: 21056196.
      Citations:    Fields:    Translation:Humans
    34. Verdoorn TA, McCarten JR, Arciniegas DB, Golden R, Moldauer L, Georgopoulos A, Lewis S, Cassano M, Hemmy L, Orr W, Rojas DC. Evaluation and tracking of Alzheimer's disease severity using resting-state magnetoencephalography. J Alzheimers Dis. 2011; 26 Suppl 3:239-55. PMID: 21971464.
      Citations: 5     Fields:    Translation:Humans
    35. Chen CL, Liu TT, Yi CH, Orr WC. Effects of capsaicin-containing red pepper sauce suspension on esophageal secondary peristalsis in humans. Neurogastroenterol Motil. 2010 Nov; 22(11):1177-82, e312-3. PMID: 20618832.
      Citations: 10     Fields:    Translation:Humans
    36. Liu TT, Yi CH, Chen CL, Orr WC. Does sleep dysfunction affect anorectal motility in healthy adults? Scand J Gastroenterol. 2010 Oct; 45(10):1262-3. PMID: 20586537.
      Citations:    Fields:    Translation:Humans
    37. Chen CL, Yi CH, Liu TT, Orr WC. Altered sensorimotor responses to esophageal acidification in older adults with GERD. Scand J Gastroenterol. 2010 Oct; 45(10):1150-5. PMID: 20545468.
      Citations: 5     Fields:    Translation:Humans
    38. Orr WC. Gastroesophageal reflux and obstructive sleep apnea: more dangers in the night. Sleep Med. 2010 Apr; 11(4):337-8. PMID: 20223704.
      Citations: 1     Fields:    Translation:Humans
    39. Dean B, Aguilar D, Shapiro C, Orr WC, Isserman JA, Calimlim B, Rippon GA. Impaired health status, daily functioning, and work productivity in adults with excessive sleepiness. J Occup Environ Med. 2010 Feb; 52(2):144-9. PMID: 20134351.
      Citations: 15     Fields:    Translation:Humans
    40. Orr WC. Review article: sleep-related gastro-oesophageal reflux as a distinct clinical entity. Aliment Pharmacol Ther. 2010 Jan; 31(1):47-56. PMID: 19691671.
      Citations: 12     Fields:    Translation:Humans
    41. Chen CL, Yi CH, Liu TT, Orr WC. Does esophageal acid sensitivity alter in older adults with gastroesophageal reflux disease? A preliminary report. J Am Geriatr Soc. 2009 Dec; 57(12):2382. PMID: 20122007.
      Citations:    Fields:    Translation:Humans
    42. Dean BB, Aguilar D, Johnson LF, Fass R, Orr WC, McGuigan JE, Calimlim B, Yan N, Morgenstern D, Dubois RW. The relationship between the prevalence of nighttime gastroesophageal reflux disease and disease severity. Dig Dis Sci. 2010 Apr; 55(4):952-9. PMID: 19693672.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    43. Orr WC, Robert JJ, Houck JR, Giddens CL, Tawk MM. The effect of acid suppression on upper airway anatomy and obstruction in patients with sleep apnea and gastroesophageal reflux disease. J Clin Sleep Med. 2009 Aug 15; 5(4):330-4. PMID: 19968010.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    44. Orr WC. Sleep and gastrointestinal disease: a new horizon in sleep medicine. Sleep Med. 2009 Jun; 10(6):595-6. PMID: 19403334.
      Citations: 2     Fields:    Translation:HumansAnimals
    45. Glidewell RN, Orr WC, Imes N. Acetazolamide as an adjunct to CPAP treatment: a case of complex sleep apnea in a patient on long-acting opioid therapy. J Clin Sleep Med. 2009 Feb 15; 5(1):63-4. PMID: 19317383.
      Citations: 4     Fields:    Translation:Humans
    46. Orr WC. CPAP and things that go "burp" in the night. J Clin Sleep Med. 2008 Oct 15; 4(5):439-40. PMID: 18853701.
      Citations:    Fields:    Translation:Humans
    47. Orr WC, Goodrich S, Fernström P, Hasselgren G. Occurrence of nighttime gastroesophageal reflux in disturbed and normal sleepers. Clin Gastroenterol Hepatol. 2008 Oct; 6(10):1099-104. PMID: 18928935.
      Citations: 5     Fields:    Translation:Humans
    48. Chen CL, Orr WC. Analysis of 24-hour esophageal pH monitoring: the effect of state of consciousness. Curr Gastroenterol Rep. 2008 Jun; 10(3):258-62. PMID: 18625136.
      Citations: 4     Fields:    Translation:Humans
    49. Mold JW, Goodrich S, Orr W. Associations between subjective night sweats and sleep study findings. J Am Board Fam Med. 2008 Mar-Apr; 21(2):96-100. PMID: 18343856.
      Citations: 2     Fields:    Translation:Humans
    50. Goodrich S, Orr WC. An investigation of the validity of the Lifeshirt in comparison to standard polysomnography in the detection of obstructive sleep apnea. Sleep Med. 2009 Jan; 10(1):118-22. PMID: 18083629.
      Citations: 9     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    51. Chen CL, Robert JJ, Orr WC. Sleep symptoms and gastroesophageal reflux. J Clin Gastroenterol. 2008 Jan; 42(1):13-7. PMID: 18097283.
      Citations: 6     Fields:    Translation:Humans
    52. Dean BB, Aguilar D, Johnson LF, McGuigan JE, Orr WC, Fass R, Yan N, Morgenstern D, Dubois RW. Night-time and daytime atypical manifestations of gastro-oesophageal reflux disease: frequency, severity and impact on health-related quality of life. Aliment Pharmacol Ther. 2008 Feb 15; 27(4):327-37. PMID: 18005248.
      Citations: 11     Fields:    Translation:Humans
    53. Orr WC. Management of nighttime gastroesophageal reflux disease. Gastroenterol Hepatol (N Y). 2007 Aug; 3(8):605-6. PMID: 21960870.
      Citations:    
    54. Dubois RW, Aguilar D, Fass R, Orr WC, Elfant AB, Dean BB, Harper AS, Yu HT, Melmed GY, Lynn R, Singh A, Tedeschi M. Consequences of frequent nocturnal gastro-oesophageal reflux disease among employed adults: symptom severity, quality of life and work productivity. Aliment Pharmacol Ther. 2007 Feb 15; 25(4):487-500. PMID: 17270005.
      Citations: 18     Fields:    Translation:Humans
    55. Orr WC. Esophageal function during sleep: another danger in the night. Sleep Med. 2007 Mar; 8(2):105-6. PMID: 17275408.
      Citations:    Fields:    Translation:Humans
    56. Orr WC, Craddock A, Goodrich S. Acidic and non-acidic reflux during sleep under conditions of powerful acid suppression. Chest. 2007 Feb; 131(2):460-5. PMID: 17296648.
      Citations: 11     Fields:    Translation:Humans
    57. Robert JJ, Elsenbruch S, Orr WC. Sleep-related autonomic disturbances in symptom subgroups of women with irritable bowel syndrome. Dig Dis Sci. 2006 Dec; 51(12):2121-7. PMID: 17080247.
      Citations: 9     Fields:    Translation:Humans
    58. Tawk M, Goodrich S, Kinasewitz G, Orr W. The effect of 1 week of continuous positive airway pressure treatment in obstructive sleep apnea patients with concomitant gastroesophageal reflux. Chest. 2006 Oct; 130(4):1003-8. PMID: 17035431.
      Citations: 24     Fields:    Translation:Humans
    59. Chen CL, Orr WC, Yang CC, Kuo TB. Cardiac autonomic regulation differentiates reflux disease with and without erosive esophagitis. Scand J Gastroenterol. 2006 Sep; 41(9):1001-6. PMID: 16938711.
      Citations: 3     Fields:    Translation:Humans
    60. Orr WC. Reflux events and sleep: are we vulnerable? Curr Gastroenterol Rep. 2006 Jun; 8(3):202-7. PMID: 16764786.
      Citations: 4     Fields:    Translation:Humans
    61. Chen CL, Reif ME, Orr WC. Effect of laparoscopic Nissen fundoplication on symptoms and gastric myoelectric activity in gastroesophageal reflux disease. J Clin Gastroenterol. 2006 Apr; 40(4):301-5. PMID: 16633101.
      Citations: 1     Fields:    Translation:Humans
    62. Orr WC. The sleeping esophagus: more food for thought. Gastroenterology. 2006 Jan; 130(1):265-6. PMID: 16401487.
      Citations:    Fields:    Translation:Humans
    63. Orr WC. Therapeutic options in the treatment of nighttime gastroesophageal reflux. Digestion. 2005; 72(4):229-38. PMID: 16319458.
      Citations: 4     Fields:    Translation:Humans
    64. Orr WC, Chen CL. Sleep and the gastrointestinal tract. Neurol Clin. 2005 Nov; 23(4):1007-24. PMID: 16243613.
      Citations: 12     Fields:    Translation:Humans
    65. Johnson DA, Orr WC, Crawley JA, Traxler B, McCullough J, Brown KA, Roth T. Effect of esomeprazole on nighttime heartburn and sleep quality in patients with GERD: a randomized, placebo-controlled trial. Am J Gastroenterol. 2005 Sep; 100(9):1914-22. PMID: 16128933.
      Citations: 38     Fields:    Translation:HumansCTClinical Trials
    66. Orr WC. Heartburn: another danger in the night? Chest. 2005 May; 127(5):1486-8. PMID: 15888817.
      Citations: 3     Fields:    Translation:Humans
    67. Orr WC, Goodrich S, Robert J. The effect of acid suppression on sleep patterns and sleep-related gastro-oesophageal reflux. Aliment Pharmacol Ther. 2005 Jan 15; 21(2):103-8. PMID: 15679759.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    68. Orr WC. Night-time gastro-oesophageal reflux disease: prevalence, hazards, and management. Eur J Gastroenterol Hepatol. 2005 Jan; 17(1):113-20. PMID: 15647651.
      Citations: 6     Fields:    Translation:Humans
    69. Chen CL, Orr WC. Comparison of esophageal motility in patients with solid dysphagia and mixed dysphagia. Dysphagia. 2005; 20(4):261-5. PMID: 16633869.
      Citations: 2     Fields:    Translation:Humans
    70. Orr WC, Heading R, Johnson LF, Kryger M. Review article: sleep and its relationship to gastro-oesophageal reflux. Aliment Pharmacol Ther. 2004 Dec; 20 Suppl 9:39-46. PMID: 15527463.
      Citations: 17     Fields:    Translation:Humans
    71. Stepnowsky CJ, Orr WC, Davidson TM. Nightly variability of sleep-disordered breathing measured over 3 nights. Otolaryngol Head Neck Surg. 2004 Dec; 131(6):837-43. PMID: 15577777.
      Citations: 26     Fields:    Translation:Humans
    72. Chen CL, Orr WC. Autonomic responses to heartburn induced by esophageal acid infusion. J Gastroenterol Hepatol. 2004 Aug; 19(8):922-6. PMID: 15242497.
      Citations: 4     Fields:    Translation:Humans
    73. Robert JJ, Orr WC, Elsenbruch S. Modulation of sleep quality and autonomic functioning by symptoms of depression in women with irritable bowel syndrome. Dig Dis Sci. 2004 Aug; 49(7-8):1250-8. PMID: 15387354.
      Citations: 8     Fields:    Translation:Humans
    74. Chen CL, Lin HH, Orr WC, Yang CC, Kuo TB. Transfer function analysis of heart rate variability in response to water intake: correlation with gastric myoelectrical activity. J Appl Physiol (1985). 2004 Jun; 96(6):2226-30. PMID: 14766782.
      Citations: 4     Fields:    Translation:Humans
    75. Orr WC. Sleep and gastroesophageal reflux disease: a wake-up call. Rev Gastroenterol Disord. 2004; 4 Suppl 4:S25-32. PMID: 15580143.
      Citations: 2     Fields:    Translation:Humans
    76. Orr WC. Masticatory movements during sleep: some food for thought. Sleep. 2003 Dec 15; 26(8):939-40. PMID: 14746371.
      Citations:    Fields:    Translation:Humans
    77. Wang ZS, Elsenbruch S, Orr WC, Chen JD. Detection of gastric slow wave uncoupling from multi-channel electrogastrogram: validations and applications. Neurogastroenterol Motil. 2003 Oct; 15(5):457-65. PMID: 14507347.
      Citations: 12     Fields:    Translation:HumansAnimals
    78. Orr WC. Sleep and gastroesophageal reflux: what are the risks? Am J Med. 2003 Aug 18; 115 Suppl 3A:109S-113S. PMID: 12928085.
      Citations: 7     Fields:    Translation:Humans
    79. Orr WC, Harnish MJ. The efficacy of omeprazole twice daily with supplemental H2 blockade at bedtime in the suppression of nocturnal oesophageal and gastric acidity. Aliment Pharmacol Ther. 2003 Jun 15; 17(12):1553-8. PMID: 12823159.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    80. Orr WC. Sleep issues in gastroesophageal reflux disease: beyond simple heartburn control. Rev Gastroenterol Disord. 2003; 3 Suppl 4:S22-9. PMID: 14671511.
      Citations: 2     Fields:    Translation:Humans
    81. Orr WC, Chen CL. Aging and neural control of the GI tract: IV. Clinical and physiological aspects of gastrointestinal motility and aging. Am J Physiol Gastrointest Liver Physiol. 2002 Dec; 283(6):G1226-31. PMID: 12433662.
      Citations: 16     Fields:    Translation:Humans
    82. Thompson JJ, Elsenbruch S, Harnish MJ, Orr WC. Autonomic functioning during REM sleep differentiates IBS symptom subgroups. Am J Gastroenterol. 2002 Dec; 97(12):3147-53. PMID: 12492202.
      Citations: 17     Fields:    Translation:Humans
    83. Qian L, Orr WC, Chen JD. Inhibitory reflexive effect of rectal distension on postprandial gastric myoelectrical activity. Dig Dis Sci. 2002 Nov; 47(11):2473-9. PMID: 12452382.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    84. Elsenbruch S, Thompson JJ, Hamish MJ, Exton MS, Orr WC. Behavioral and physiological sleep characteristics in women with irritable bowel syndrome. Am J Gastroenterol. 2002 Sep; 97(9):2306-14. PMID: 12358249.
      Citations: 12     Fields:    Translation:Humans
    85. Miner P, Orr W, Filippone J, Jokubaitis L, Sloan S. Rabeprazole in nonerosive gastroesophageal reflux disease: a randomized placebo-controlled trial. Am J Gastroenterol. 2002 Jun; 97(6):1332-9. PMID: 12094846.
      Citations: 43     Fields:    Translation:HumansCTClinical Trials
    86. Chen CL, Orr WC, Verlinden MH, Dettmer A, Brinkhoff H, Riff D, Schwartz S, Soloway RD, Krause R, Lanza F, Mack RJ. Efficacy of a motilin receptor agonist (ABT-229) for the treatment of gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2002 Apr; 16(4):749-57. PMID: 11929393.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    87. Orr WC. Sleep-related breathing disorders: is it all about apnea? Chest. 2002 Jan; 121(1):8-11. PMID: 11796424.
      Citations: 1     Fields:    Translation:Humans
    88. Elsenbruch S, Lovallo WR, Orr WC. Psychological and physiological responses to postprandial mental stress in women with the irritable bowel syndrome. Psychosom Med. 2001 Sep-Oct; 63(5):805-13. PMID: 11573029.
      Citations: 12     Fields:    Translation:Humans
    89. Orr WC, Chen CL, Sloan S. The role of age and salivation in acid clearance in symptomatic patients with gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2001 Sep; 15(9):1385-8. PMID: 11552909.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    90. Orr WC. Gastrointestinal functioning during sleep: a new horizon in sleep medicine. Sleep Med Rev. 2001 Apr; 5(2):91-101. PMID: 12531048.
      Citations: 5     Fields:    
    91. Elsenbruch S, Orr WC. Diarrhea- and constipation-predominant IBS patients differ in postprandial autonomic and cortisol responses. Am J Gastroenterol. 2001 Feb; 96(2):460-6. PMID: 11232691.
      Citations: 35     Fields:    Translation:Humans
    92. Orr WC, Elsenbruch S, Harnish MJ. Autonomic regulation of cardiac function during sleep in patients with irritable bowel syndrome. Am J Gastroenterol. 2000 Oct; 95(10):2865-71. PMID: 11051361.
      Citations: 22     Fields:    Translation:Humans
    93. Orr WC. Sleep and functional bowel disorders: can bad bowels cause bad dreams? Am J Gastroenterol. 2000 May; 95(5):1118-21. PMID: 10811314.
      Citations: 4     Fields:    Translation:Humans
    94. Elsenbruch S, Wang Z, Orr WC, Chen JD. Time-frequency analysis of heart rate variability using short-time fourier analysis. Physiol Meas. 2000 May; 21(2):229-40. PMID: 10847190.
      Citations: 5     Fields:    Translation:Humans
    95. Orr WC, Zhang M, McClanahan J, Sloan S, Chen JD. Gastric myoelectric activity in older adults treated with cisapride for gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2000 Mar; 14(3):337-43. PMID: 10735928.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    96. Orr WC, Elsenbruch S, Harnish MJ, Johnson LF. Proximal migration of esophageal acid perfusions during waking and sleep. Am J Gastroenterol. 2000 Jan; 95(1):37-42. PMID: 10638556.
      Citations: 13     Fields:    Translation:Humans
    97. Elsenbruch S, Harnish MJ, Orr WC. Heart rate variability during waking and sleep in healthy males and females. Sleep. 1999 Dec 15; 22(8):1067-71. PMID: 10617167.
      Citations: 35     Fields:    Translation:Humans
    98. Elsenbruch S, Harnish MJ, Orr WC. Subjective and objective sleep quality in irritable bowel syndrome. Am J Gastroenterol. 1999 Sep; 94(9):2447-52. PMID: 10484007.
      Citations: 20     Fields:    Translation:Humans
    99. Elsenbruch S, Orr WC, Harnish MJ, Chen JD. Disruption of normal gastric myoelectric functioning by sleep. Sleep. 1999 Jun 15; 22(4):453-8. PMID: 10389221.
      Citations: 5     Fields:    Translation:Humans
    100. Castell D, Silvers D, Littlejohn T, Orr W, Napolitano J, Oleka N, Jokubaitis L. Cisapride 20 mg b.d. for preventing symptoms of GERD induced by a provocative meal. The CIS-USA-89 Study Group. Aliment Pharmacol Ther. 1999 Jun; 13(6):787-94. PMID: 10383509.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    101. Lu CL, Zou X, Orr WC, Chen JD. Postprandial changes of sympathovagal balance measured by heart rate variability. Dig Dis Sci. 1999 Apr; 44(4):857-61. PMID: 10219849.
      Citations: 36     Fields:    Translation:Humans
    102. Lu CL, Montgomery P, Zou X, Orr WC, Chen JD. Gastric myoelectrical activity in patients with cervical spinal cord injury. Am J Gastroenterol. 1998 Dec; 93(12):2391-6. PMID: 9860398.
      Citations: 12     Fields:    Translation:Humans
    103. Chen JD, Lin X, Zhang M, Torres-Pinedo RB, Orr WC. Gastric myoelectrical activity in healthy children and children with functional dyspepsia. Dig Dis Sci. 1998 Nov; 43(11):2384-91. PMID: 9824123.
      Citations: 10     Fields:    Translation:Humans
    104. Orr WC, Harnish MJ. Sleep-related gastro-oesophageal reflux: provocation with a late evening meal and treatment with acid suppression. Aliment Pharmacol Ther. 1998 Oct; 12(10):1033-8. PMID: 9798810.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    105. Harnish MJ, Greenleaf SR, Orr WC. A comparison of feeding to cephalic stimulation on postprandial sleepiness. Physiol Behav. 1998 Apr; 64(1):93-6. PMID: 9661987.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    106. Levanon D, Zhang M, Orr WC, Chen JD. Effects of meal volume and composition on gastric myoelectrical activity. Am J Physiol. 1998 02; 274(2):G430-4. PMID: 9486200.
      Citations: 16     Fields:    Translation:Humans
    107. Orr WC, Johnson LF. Responses to different levels of esophageal acidification during waking and sleep. Dig Dis Sci. 1998 Feb; 43(2):241-5. PMID: 9512113.
      Citations: 10     Fields:    Translation:Humans
    108. Orr WC, Shadid G, Harnish MJ, Elsenbruch S. Meal composition and its effect on postprandial sleepiness. Physiol Behav. 1997 Oct; 62(4):709-12. PMID: 9284488.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    109. Orr WC, Crowell MD, Lin B, Harnish MJ, Chen JD. Sleep and gastric function in irritable bowel syndrome: derailing the brain-gut axis. Gut. 1997 Sep; 41(3):390-3. PMID: 9378397.
      Citations: 17     Fields:    Translation:Humans
    110. Chen JD, Co E, Liang J, Pan J, Sutphen J, Torres-Pinedo RB, Orr WC. Patterns of gastric myoelectrical activity in human subjects of different ages. Am J Physiol. 1997 May; 272(5 Pt 1):G1022-7. PMID: 9176209.
      Citations: 19     Fields:    Translation:Humans
    111. Orr WC, Johnson P, Yates C. Chronic constipation: a clinical conundrum. J Am Geriatr Soc. 1997 May; 45(5):652-3. PMID: 9158596.
      Citations:    Fields:    Translation:Humans
    112. Chen JD, Pan J, Orr WC. Role of sham feeding in postprandial changes of gastric myoelectrical activity. Dig Dis Sci. 1996 Sep; 41(9):1706-12. PMID: 8794783.
      Citations: 5     Fields:    Translation:Humans
    113. Shoenut JP, Yamashiro Y, Orr WC, Kerr P, Micflikier AB, Kryger MH. Effect of severe gastroesophageal reflux on sleep stage in patients with aperistaltic esophagus. Dig Dis Sci. 1996 Feb; 41(2):372-6. PMID: 8601385.
      Citations: 2     Fields:    Translation:Humans
    114. Orr WC, Mellow MH, Grossman MR. Patterns of 24-hour oesophageal acid exposure after acute withdrawal of acid suppression. Aliment Pharmacol Ther. 1995 Oct; 9(5):571-4. PMID: 8580280.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    115. Orr WC. Sleep and esophageal function: brain talk. Am J Gastroenterol. 1995 Apr; 90(4):667-9. PMID: 7717338.
      Citations:    Fields:    Translation:Humans
    116. Vanoli E, Adamson PB, Pinna GD, Lazzara R, Orr WC. Heart rate variability during specific sleep stages. A comparison of healthy subjects with patients after myocardial infarction. Circulation. 1995 Apr 01; 91(7):1918-22. PMID: 7895347.
      Citations: 59     Fields:    Translation:Humans
    117. Orr WC. The physiology and philosophy of cause and effect. Gastroenterology. 1994 Dec; 107(6):1898-901. PMID: 7958711.
      Citations: 7     Fields:    Translation:Humans
    118. Orr WC, Duke JC, Imes NK, Mellow MH. Comparative effects of H2-receptor antagonists on subjective and objective assessments of sleep. Aliment Pharmacol Ther. 1994 Apr; 8(2):203-7. PMID: 8038352.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    119. Orr WC, Allen ML, Robinson M. The pattern of nocturnal and diurnal esophageal acid exposure in the pathogenesis of erosive mucosal damage. Am J Gastroenterol. 1994 Apr; 89(4):509-12. PMID: 8147351.
      Citations: 24     Fields:    Translation:Humans
    120. Orr WC, Eiken T, Pegram V, Jones R, Rundell OH. A laboratory validation study of a portable system for remote recording of sleep-related respiratory disorders. Chest. 1994 Jan; 105(1):160-2. PMID: 8275725.
      Citations: 2     Fields:    Translation:Humans
    121. Orr WC. The irritable bowel syndrome: in your dreams? Am J Gastroenterol. 1993 May; 88(5):781-3. PMID: 8480751.
      Citations:    Fields:    Translation:Humans
    122. Orr WC. Sleep studies in OSA patients before CPAP treatment. One night or two? Chest. 1993 Feb; 103(2):652-3. PMID: 8432185.
      Citations:    Fields:    Translation:Humans
    123. Orr WC. Chest pain and the esophagus: is it more obvious in the CCU? Am J Gastroenterol. 1992 Sep; 87(9):1221-3. PMID: 1519590.
      Citations:    Fields:    Translation:Humans
    124. Orr WC, Shamma-Othman Z, Allen M, Robinson MG. Esophageal function and gastroesophageal reflux during sleep and waking in patients with chronic obstructive pulmonary disease. Chest. 1992 Jun; 101(6):1521-5. PMID: 1600768.
      Citations: 7     Fields:    Translation:Humans
    125. Orr WC. Snoring. A major health risk? Chest. 1992 Apr; 101(4):889-90. PMID: 1555454.
      Citations:    Fields:    Translation:Humans
    126. Russell J, Orr WC, Wilson T, Finn AL. Effects of ranitidine, given t.d.s., on intragastric and oesophageal pH in patients with gastrooesophageal reflux. Aliment Pharmacol Ther. 1991 Dec; 5(6):621-30. PMID: 1782305.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    127. Orr WC. Noncardiac chest pain: conundrum of cause and effect. Am J Gastroenterol. 1991 Oct; 86(10):1548-50. PMID: 1928056.
      Citations: 1     Fields:    Translation:Humans
    128. Orr WC, Othman JA, Rundell OH. Genetic markers in familial narcolepsy. Sleep. 1991 Jun; 14(3):270-1. PMID: 1896730.
      Citations:    Fields:    Translation:Humans
    129. Orr WC, Robinson MG, Johnson LF. The effect of esophageal acid volume on arousals from sleep and acid clearance. Chest. 1991 Feb; 99(2):351-4. PMID: 1989794.
      Citations: 6     Fields:    Translation:Humans
    130. Orr WC, Finn A, Wilson T, Russell J. Esophageal acid contact time and heartburn in acute treatment with ranitidine and metoclopramide. Am J Gastroenterol. 1990 Jun; 85(6):697-700. PMID: 2191595.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    131. Allen ML, Mellow MH, Robinson MG, Orr WC. The effect of raw onions on acid reflux and reflux symptoms. Am J Gastroenterol. 1990 Apr; 85(4):377-80. PMID: 2327378.
      Citations: 11     Fields:    Translation:HumansAnimals
    132. Orr WC, Shamma-Othman Z, Levin D, Othman J, Rundell OH. Persistent hypoxemia and excessive daytime sleepiness in chronic obstructive pulmonary disease (COPD). Chest. 1990 Mar; 97(3):583-5. PMID: 2306962.
      Citations: 7     Fields:    Translation:Humans
    133. Allen ML, Robinson MG, Orr WC. Lower esophageal sphincter pressure, esophageal body motor functioning, and esophageal acid sensitivity. Scand J Gastroenterol. 1989 Nov; 24(9):1129-34. PMID: 2595275.
      Citations:    Fields:    Translation:Humans
    134. Orr WC, Finn AL, Allen M, Robinson MG, Wilson T. The timing of evening meal and ranitidine administration--effects on patterns of 24 hour intragastric acidity. Aliment Pharmacol Ther. 1988 Dec; 2(6):541-9. PMID: 2979277.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    135. Bonham PE, Currier GF, Orr WC, Othman J, Nanda RS. The effect of a modified functional appliance on obstructive sleep apnea. Am J Orthod Dentofacial Orthop. 1988 Nov; 94(5):384-92. PMID: 3189241.
      Citations: 15     Fields:    Translation:Humans
    136. Allen ML, Orr WC, Mellow MH, Robinson MG. Water swallows versus food ingestion as manometric tests for esophageal dysfunction. Gastroenterology. 1988 Sep; 95(3):831-3. PMID: 3273752.
      Citations: 13     Fields:    Translation:Humans
    137. Orr WC, Lackey C, Robinson MG, Johnson LF, Welsh JD. Esophageal acid clearance during sleep in patients with Barrett's esophagus. Dig Dis Sci. 1988 Jun; 33(6):654-9. PMID: 3371137.
      Citations: 9     Fields:    Translation:Humans
    138. Orr WC, Robinson MG, Humphries TJ, Antonello J, Cagliola A. Dose--response effect of famotidine on patterns of gastro-oesophageal reflux. Aliment Pharmacol Ther. 1988 Jun; 2(3):229-35. PMID: 2979247.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    139. Allen ML, Orr WC, Woodruff DM, Robinson MG. Validation of an ambulatory esophageal pH monitoring system. Am J Gastroenterol. 1988 Mar; 83(3):287-90. PMID: 3344731.
      Citations: 1     Fields:    Translation:Humans
    140. Allen ML, Orr WC, Robinson MG. Anorectal functioning in fecal incontinence. Dig Dis Sci. 1988 Jan; 33(1):36-40. PMID: 3338357.
      Citations: 6     Fields:    Translation:Humans
    141. Orr WC, Levine NS, Buchanan RT. Effect of cleft palate repair and pharyngeal flap surgery on upper airway obstruction during sleep. Plast Reconstr Surg. 1987 Aug; 80(2):226-32. PMID: 3602172.
      Citations: 9     Fields:    Translation:Humans
    142. Robinson MG, Orr WC, McCallum R, Nardi R. Do endoscopic findings influence response to H2 antagonist therapy for gastroesophageal reflux disease? Am J Gastroenterol. 1987 Jun; 82(6):519-22. PMID: 3554990.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    143. Allen M, Mellow M, Robinson MG, Orr WC. Comparison of calcium channel blocking agents and an anticholinergic agent on oesophageal function. Aliment Pharmacol Ther. 1987 Apr; 1(2):153-9. PMID: 2979217.
      Citations: 4     Fields:    Translation:Humans
    144. Allen M, Orr WC. Importance of adequate controls in experimental design. Gastroenterology. 1987 Jan; 92(1):271. PMID: 3781199.
      Citations:    Fields:    Translation:Humans
    145. Toubas PL, Duke JC, McCaffree MA, Mattice CD, Bendell D, Orr WC. Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study. Pediatrics. 1986 Jul; 78(1):159-63. PMID: 3725488.
      Citations: 6     Fields:    Translation:Humans
    146. Orr WC. Sleep apnea, hypoxemia, and cardiac arrhythmias. Chest. 1986 Jan; 89(1):1-2. PMID: 3940767.
      Citations: 3     Fields:    Translation:Humans
    147. Orr WC. Utilization of polysomnography in the assessment of sleep disorders. Med Clin North Am. 1985 Nov; 69(6):1153-67. PMID: 3934480.
      Citations: 5     Fields:    Translation:Humans
    148. Moran WB, Orr WC. Diagnosis and management of obstructive sleep apnea. Part II. Arch Otolaryngol. 1985 Oct; 111(10):650-8. PMID: 4038137.
      Citations: 1     Fields:    Translation:Humans
    149. Orr WC, Moran WB. Diagnosis and management of obstructive sleep apnea. A multidisciplinary approach. Arch Otolaryngol. 1985 Sep; 111(9):583-8. PMID: 4026674.
      Citations: 2     Fields:    Translation:Humans
    150. Allen ML, Orr WC, Woodruff DM, Duke JC, Robinson MG. The effects of swallowing frequency and transdermal scopolamine on esophageal acid clearance. Am J Gastroenterol. 1985 Sep; 80(9):669-72. PMID: 4036944.
      Citations: 1     Fields:    Translation:Humans
    151. Orr WC, Stahl ML, Duke J, McCaffree MA, Toubas P, Mattice C, Krous HF. Effect of sleep state and position on the incidence of obstructive and central apnea in infants. Pediatrics. 1985 May; 75(5):832-5. PMID: 3991268.
      Citations: 9     Fields:    Translation:Humans
    152. Stahl ML, Orr WC, Males JL. Progesterone levels and sleep-related breathing during menstrual cycles of normal women. Sleep. 1985; 8(3):227-30. PMID: 4048738.
      Citations: 4     Fields:    Translation:Humans
    153. Moran WB, Orr WC, Fixley MS, Wittels EE. Nonhypersomnolent patients with obstructive sleep apnea. Otolaryngol Head Neck Surg. 1984 Dec; 92(6):608-10. PMID: 6440074.
      Citations: 1     Fields:    Translation:Humans
    154. Orr WC, Johnson LF, Robinson MG. Effect of sleep on swallowing, esophageal peristalsis, and acid clearance. Gastroenterology. 1984 May; 86(5 Pt 1):814-9. PMID: 6706065.
      Citations: 34     Fields:    Translation:Humans
    155. Orr WC. Sleep and breathing: an overview. Ear Nose Throat J. 1984 May; 63(5):191-8. PMID: 6734478.
      Citations:    Fields:    Translation:Humans
    156. Orr WC. Sleep-related breathing disorders. An update. Chest. 1983 Oct; 84(4):475-80. PMID: 6352198.
      Citations:    Fields:    Translation:Humans
    157. Stahl ML, Orr WC, Bollinger C. Postprandial sleepiness: objective documentation via polysomnography. Sleep. 1983; 6(1):29-35. PMID: 6844795.
      Citations: 6     Fields:    Translation:HumansAnimals
    158. Orr WC, Robinson MG. Hypertensive peristalsis in the pathogenesis of chest pain: further exploration of the "nutcracker" esophagus. Am J Gastroenterol. 1982 Sep; 77(9):604-7. PMID: 7114023.
      Citations: 4     Fields:    Translation:Humans
    159. Coleman RM, Roffwarg HP, Kennedy SJ, Guilleminault C, Cinque J, Cohn MA, Karacan I, Kupfer DJ, Lemmi H, Miles LE, Orr WC, Phillips ER, Roth T, Sassin JF, Schmidt HS, Weitzman ED, Dement WC. Sleep-wake disorders based on a polysomnographic diagnosis. A national cooperative study. JAMA. 1982 Feb 19; 247(7):997-1003. PMID: 7057593.
      Citations: 42     Fields:    Translation:Humans
    160. Whitehead WE, Orr WC, Engel BT, Schuster MM. External anal sphincter response to rectal distention: learned response or reflex. Psychophysiology. 1982 Jan; 19(1):57-62. PMID: 7058240.
      Citations: 9     Fields:    Translation:Humans
    161. Prigatano GP, Stahl ML, Orr WC, Zeiner HK. Sleep and dreaming disturbances in closed head injury patients. J Neurol Neurosurg Psychiatry. 1982 Jan; 45(1):78-80. PMID: 7062076.
      Citations: 9     Fields:    Translation:Humans
    162. Orr WC, Robinson MG. The sleeping gut. Med Clin North Am. 1981 Nov; 65(6):1359-76. PMID: 7035769.
      Citations: 4     Fields:    Translation:Humans
    163. Karacan I, Orr W, Roth T, Kramer M, Thornby J, Bingham S, Kay D. Dose-related effects of phenobarbitone on human sleep-waking patterns. Br J Clin Pharmacol. 1981 Sep; 12(3):303-13. PMID: 7295460.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    164. Orr WC, Martin RJ. Obstructive sleep apnea associated with tonsillar hypertrophy in adults. Arch Intern Med. 1981 Jul; 141(8):990-2. PMID: 7247607.
      Citations: 11     Fields:    Translation:Humans
    165. Orr WC, Males JL, Imes NK. Myxedema and obstructive sleep apnea. Am J Med. 1981 May; 70(5):1061-6. PMID: 7234872.
      Citations: 13     Fields:    Translation:Humans
    166. Orr WC, Robinson MG, Johnson LF. Acid clearance during sleep in the pathogenesis of reflux esophagitis. Dig Dis Sci. 1981 May; 26(5):423-7. PMID: 7249882.
      Citations: 29     Fields:    Translation:Humans
    167. Sauerland EK, Orr WC, Hairston LE. DMG patterns of oropharyngeal muscles during respiration in wakefulness and sleep. Electromyogr Clin Neurophysiol. 1981 Feb-Mar; 21(2-3):307-16. PMID: 7262010.
      Citations: 11     Fields:    Translation:Humans
    168. Karacan I, Orr W, Roth T, Kramer M, Thornby J, Bingham S, Kay D. Dose-related effects of flurazepam on human sleep-walking patterns. Psychopharmacology (Berl). 1981; 73(4):332-9. PMID: 6789354.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    169. Martin RJ, Pennock BE, Orr WC, Sanders MH, Rogers RM. Respiratory mechanics and timing during sleep in occlusive sleep apnea. J Appl Physiol Respir Environ Exerc Physiol. 1980 Mar; 48(3):432-7. PMID: 7372513.
      Citations: 9     Fields:    Translation:Humans
    170. Orr WC. Arousals from sleep: is a good night's sleep really good? Int J Neurosci. 1980; 11(2):143-4. PMID: 7191838.
      Citations:    Fields:    Translation:HumansAnimals
    171. Orr WC, Martin RJ, Imes NK, Rogers RM, Stahl ML. Hypersomnolent and nonhypersomnolent patients with upper airway obstruction during sleep. Chest. 1979 Apr; 75(4):418-22. PMID: 221152.
      Citations: 7     Fields:    Translation:Humans
    172. Kreutzer DL, Desai U, Orr W, Showell H, Ward PA. Induction of acute inflammatory reactions in lung following intrapulmonary instillation of preformed chemotactic peptides and purified complement components. Chest. 1979 Feb; 75(2 Suppl):259-62. PMID: 436469.
      Citations: 7     Fields:    Translation:HumansAnimals
    173. Orr WC, Stahl ML, Whitsett T, Langevin E. Physiological sleep patterns and cardiac arrhythmias. Am Heart J. 1979 Jan; 97(1):128-9. PMID: 215022.
      Citations:    Fields:    Translation:Humans
    174. Orr WC, Imes NK, Martin RJ. Progesterone therapy in obese patients with sleep apnea. Arch Intern Med. 1979 Jan; 139(1):109-11. PMID: 216329.
      Citations: 13     Fields:    Translation:Humans
    175. Mangat D, Orr WC, Smith RO. Sleep apnea, hypersomnolence, and upper airway obstruction secondary to adenotonsillar enlargement. Arch Otolaryngol. 1977 Jul; 103(7):383-6. PMID: 880101.
      Citations: 7     Fields:    Translation:Humans
    176. Imes NK, Orr WC, Smith RO, Rogers RM. Retrognathia and sleep apnea. A life-threatening condition masquerading as narcolepsy. JAMA. 1977 Apr 11; 237(15):1596-7. PMID: 576659.
      Citations: 3     Fields:    Translation:Humans
    177. Orr WC, Stahl ML. Sleep disturbances after open heart surgery. Am J Cardiol. 1977 Feb; 39(2):196-201. PMID: 299975.
      Citations: 17     Fields:    Translation:Humans
    178. Orr WC, Vogel GW, Stahl ML, Griffiths WJ, Seely JR. Sleep patterns in growth hormone deficient children and age-matched controls: developmental considerations. Neuroendocrinology. 1977; 24(5-6):347-52. PMID: 205813.
      Citations: 3     Fields:    Translation:Humans
    179. Anch M, Orr WC, Karacan I. Stress, cardiac activity and sleep. J Human Stress. 1976 Sep; 2(3):15-24. PMID: 190312.
      Citations:    Fields:    Translation:Humans
    180. Orr WC, Hall WH, Stahl ML, Durkin MG, Whitsett TL. Sleep patterns and gastric acid secretion in duodenal ucler disease. Arch Intern Med. 1976 Jun; 136(6):655-60. PMID: 179485.
      Citations: 9     Fields:    Translation:Humans
    181. Hall WH, Orr WC. Letter: Gastric secretion during sleep. Gastroenterology. 1976 Mar; 70(3):465. PMID: 1248704.
      Citations:    Fields:    Translation:Humans
    182. Orr WC, Shappell SD. Letter: REM sleep and cardiac arrhythmias. Circulation. 1975 Sep; 52(3):519. PMID: 168989.
      Citations:    Fields:    Translation:Humans
    183. Shappell SD, Orr WC. Variant angina and sleep: a case report with therapeutic considerations. Dis Nerv Syst. 1975 Jun; 36(6):295-8. PMID: 807462.
      Citations: 2     Fields:    Translation:Humans
    184. Shappell SD, Orr W, Gunn CG. The ballooning posterior leaflet syndrome: Minnesota Multiphasic Personality Inventory profiles in symptomatic and asymptomatic groups. Chest. 1974 Dec; 66(6):690-2. PMID: 4154184.
      Citations: 1     Fields:    Translation:Humans
    185. Orr WC, Hoffman HJ, Hegge FW. Ultradian rhythms in extended performance. Aerosp Med. 1974 Sep; 45(9):995-1000. PMID: 4416768.
      Citations: 3     Fields:    Translation:Humans
    186. Orr WC, Hoffman HJ. A 90-min cardiac biorhythm: methodology and data analysis using modified periodograms and complex demodulation. IEEE Trans Biomed Eng. 1974 Mar; 21(2):130-43. PMID: 4818799.
      Citations: 2     Fields:    Translation:Humans
    187. Gerber MA, Orr W, Denk H, Schaffner F, Popper H. Hepatocellular hyalin in cholestasis and cirrhosis: its diagnostic significance. Gastroenterology. 1973 Jan; 64(1):89-98. PMID: 4119149.
      Citations: 15     Fields:    Translation:Humans
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