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Nancy Wakeham

TitleAsst,Research III
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentCell Biology
AddressBRC 264
975 NE 10th St
Oklahoma City OK 73104
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nammalwar B, Bourne CR, Wakeham N, Bourne PC, Barrow EW, Muddala NP, Bunce RA, Berlin KD, Barrow WW. Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis. Bioorg Med Chem. 2015 Jan 01; 23(1):203-11. PMID: 25435253.
      Citations: 4     Fields:    Translation:Cells
    2. Hanigan MH, Gillies EM, Wickham S, Wakeham N, Wirsig-Wiechmann CR. Immunolabeling of gamma-glutamyl transferase 5 in normal human tissues reveals that expression and localization differ from gamma-glutamyl transferase 1. Histochem Cell Biol. 2015 May; 143(5):505-15. PMID: 25377544.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    3. Bourne CR, Wakeham N, Webb N, Nammalwar B, Bunce RA, Berlin KD, Barrow WW. The structure and competitive substrate inhibition of dihydrofolate reductase from Enterococcus faecalis reveal restrictions to cofactor docking. Biochemistry. 2014 Feb 25; 53(7):1228-38. PMID: 24495113.
      Citations: 2     Fields:    Translation:Cells
    4. Bourne CR, Wakeham N, Nammalwar B, Tseitin V, Bourne PC, Barrow EW, Mylvaganam S, Ramnarayan K, Bunce RA, Berlin KD, Barrow WW. Structure-activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase. Biochim Biophys Acta. 2013 Jan; 1834(1):46-52. PMID: 22999981.
      Citations: 5     Fields:    Translation:Cells
    5. Nammalwar B, Bourne CR, Bunce RA, Wakeham N, Bourne PC, Ramnarayan K, Mylvaganam S, Berlin KD, Barrow EW, Barrow WW. Inhibition of bacterial dihydrofolate reductase by 6-alkyl-2,4-diaminopyrimidines. ChemMedChem. 2012 Nov; 7(11):1974-82. PMID: 22930550.
      Citations: 5     Fields:    Translation:HumansCells
    6. Bourne CR, Wakeham N, Bunce RA, Nammalwar B, Berlin KD, Barrow WW. Classifying compound mechanism of action for linking whole cell phenotypes to molecular targets. J Mol Recognit. 2012 Apr; 25(4):216-23. PMID: 22434711.
      Citations: 3     Fields:    Translation:Cells
    7. Li F, Chvyrkova I, Terzyan S, Wakeham N, Turner R, Ghosh AK, Zhang XC, Tang J. Inhibition of anthrax lethal factor: lability of hydroxamate as a chelating group. Appl Microbiol Biotechnol. 2012 May; 94(4):1041-9. PMID: 22270239.
      Citations: 6     Fields:    Translation:AnimalsCells
    8. Zhu G, Chen J, Liu J, Brunzelle JS, Huang B, Wakeham N, Terzyan S, Li X, Rao Z, Li G, Zhang XC. Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. EMBO J. 2007 Jul 25; 26(14):3484-93. PMID: 17581628.
      Citations: 64     Fields:    Translation:HumansCells
    9. Zhu G, Zhai P, Wakeham N, He X, Zhang XC. Analysis of the interaction between GGA1 GAT domain and Rabaptin-5. Methods Enzymol. 2005; 403:583-92. PMID: 16473621.
      Citations: 1     Fields:    Translation:HumansCells
    10. Zhu G, Zhai P, He X, Wakeham N, Rodgers K, Li G, Tang J, Zhang XC. Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5. EMBO J. 2004 Oct 13; 23(20):3909-17. PMID: 15457209.
      Citations: 7     Fields:    Translation:HumansCells
    11. Terzyan S, Wakeham N, Zhai P, Rodgers K, Zhang XC. Characterization of Lys-698-to-Met substitution in human plasminogen catalytic domain. Proteins. 2004 Aug 01; 56(2):277-84. PMID: 15211511.
      Citations: 1     Fields:    Translation:HumansCells
    12. Zhai P, He X, Liu J, Wakeham N, Zhu G, Li G, Tang J, Zhang XC. The interaction of the human GGA1 GAT domain with rabaptin-5 is mediated by residues on its three-helix bundle. Biochemistry. 2003 Dec 02; 42(47):13901-8. PMID: 14636058.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    13. Zhai P, Wakeham N, Loy JA, Zhang XC. Functional roles of streptokinase C-terminal flexible peptide in active site formation and substrate recognition in plasminogen activation. Biochemistry. 2003 Jan 14; 42(1):114-20. PMID: 12515545.
      Citations: 4     Fields:    Translation:HumansCells
    14. Wakeham N, Terzyan S, Zhai P, Loy JA, Tang J, Zhang XC. Effects of deletion of streptokinase residues 48-59 on plasminogen activation. Protein Eng. 2002 Sep; 15(9):753-61. PMID: 12456874.
      Citations: 14     Fields:    Translation:HumansCells
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