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Narcis Popescu

TitleResearch Assistant Member
InstitutionOklahoma Medical Research Foundation
DepartmentArthritis and Clinical Immunology
Address825 N.E. 13th Street
Oklahoma City OK 73104
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Popescu NI, Lupu C, Lupu F. Disseminated intravascular coagulation and its immune mechanisms. Blood. 2022 03 31; 139(13):1973-1986. PMID: 34428280.
      Citations:    Fields:    Translation:Humans
    2. Popescu NI, Cochran J, Duggan E, Kluza J, Silasi R, Coggeshall KM. Internalization of Polymeric Bacterial Peptidoglycan Occurs through Either Actin or Dynamin Dependent Pathways. Microorganisms. 2022 Mar 03; 10(3). PMID: 35336127.
    3. Keshari RS, Popescu NI, Silasi R, Regmi G, Lupu C, Simmons JH, Ricardo A, Coggeshall KM, Lupu F. Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons. Proc Natl Acad Sci U S A. 2021 09 14; 118(37). PMID: 34507997.
      Citations: 1     Fields:    Translation:AnimalsCells
    4. Keshari RS, Silasi R, Popescu NI, Regmi G, Chaaban H, Lambris JD, Lupu C, Mollnes TE, Lupu F. CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis. J Thromb Haemost. 2021 02; 19(2):429-443. PMID: 33174372.
      Citations: 2     Fields:    Translation:AnimalsCells
    5. Popescu NI, Keshari RS, Cochran J, Coggeshall KM, Lupu F. C3 Opsonization of Anthrax Bacterium and Peptidoglycan Supports Recognition and Activation of Neutrophils. Microorganisms. 2020 Jul 13; 8(7). PMID: 32668703.
    6. Keshari RS, Silasi R, Popescu NI, Georgescu C, Chaaban H, Lupu C, McCarty OJT, Esmon CT, Lupu F. Fondaparinux pentasaccharide reduces sepsis coagulopathy and promotes survival in the baboon model of Escherichia coli sepsis. J Thromb Haemost. 2020 01; 18(1):180-190. PMID: 31549765.
      Citations: 8     Fields:    Translation:AnimalsCells
    7. Popescu NI, Girton A, Burgett T, Lovelady K, Coggeshall KM. Monocyte procoagulant responses to anthrax peptidoglycan are reinforced by proinflammatory cytokine signaling. Blood Adv. 2019 08 27; 3(16):2436-2447. PMID: 31416821.
      Citations: 6     Fields:    Translation:HumansCells
    8. Popescu NI, Silasi R, Keshari RS, Girton A, Burgett T, Zeerleder SS, Gailani D, Gruber A, Lupu F, Coggeshall KM. Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways. Blood. 2018 08 23; 132(8):849-860. PMID: 29921614.
      Citations: 17     Fields:    Translation:AnimalsCells
    9. Girton AW, Popescu NI, Keshari RS, Burgett T, Lupu F, Coggeshall KM. Serum Amyloid P and IgG Exhibit Differential Capabilities in the Activation of the Innate Immune System in Response to Bacillus anthracis Peptidoglycan. Infect Immun. 2018 05; 86(5). PMID: 29531132.
      Citations: 7     Fields:    Translation:HumansCells
    10. Langer M, Girton AW, Popescu NI, Burgett T, Metcalf JP, Coggeshall KM. Neither Lys- and DAP-type peptidoglycans stimulate mouse or human innate immune cells via Toll-like receptor 2. PLoS One. 2018; 13(2):e0193207. PMID: 29474374.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    11. Keshari RS, Silasi R, Popescu NI, Patel MM, Chaaban H, Lupu C, Coggeshall KM, Mollnes TE, DeMarco SJ, Lupu F. Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis. Proc Natl Acad Sci U S A. 2017 Aug 01; 114(31):E6390-E6399. PMID: 28720697.
      Citations: 41     Fields:    
    12. Wolf AJ, Reyes CN, Liang W, Becker C, Shimada K, Wheeler ML, Cho HC, Popescu NI, Coggeshall KM, Arditi M, Underhill DM. Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. Cell. 2016 Jul 28; 166(3):624-636. PMID: 27374331.
      Citations: 189     Fields:    Translation:HumansAnimalsCells
    13. Silasi-Mansat R, Zhu H, Georgescu C, Popescu N, Keshari RS, Peer G, Lupu C, Taylor FB, Pereira HA, Kinasewitz G, Lambris JD, Lupu F. Complement inhibition decreases early fibrogenic events in the lung of septic baboons. J Cell Mol Med. 2015 Nov; 19(11):2549-63. PMID: 26337158.
      Citations: 21     Fields:    Translation:Animals
    14. Chaaban H, Keshari RS, Silasi-Mansat R, Popescu NI, Mehta-D'Souza P, Lim YP, Lupu F. Inter-a inhibitor protein and its associated glycosaminoglycans protect against histone-induced injury. Blood. 2015 Apr 02; 125(14):2286-96. PMID: 25631771.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    15. Keshari RS, Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Chaaban H, Lambris JD, Polf H, Lupu C, Kinasewitz G, Lupu F. Acute lung injury and fibrosis in a baboon model of Escherichia coli sepsis. Am J Respir Cell Mol Biol. 2014 Feb; 50(2):439-50. PMID: 24066737.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    16. Sun D, Popescu NI, Raisley B, Keshari RS, Dale GL, Lupu F, Coggeshall KM. Bacillus anthracis peptidoglycan activates human platelets through Fc?RII and complement. Blood. 2013 Jul 25; 122(4):571-9. PMID: 23733338.
      Citations: 17     Fields:    Translation:HumansCells
    17. Lupu C, Zhu H, Popescu NI, Wren JD, Lupu F. Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen. Blood. 2011 Oct 20; 118(16):4463-71. PMID: 21868574.
      Citations: 39     Fields:    Translation:HumansCells
    18. Zhang X, Yu H, Lou JR, Zheng J, Zhu H, Popescu NI, Lupu F, Lind SE, Ding WQ. MicroRNA-19 (miR-19) regulates tissue factor expression in breast cancer cells. J Biol Chem. 2011 Jan 14; 286(2):1429-35. PMID: 21059650.
      Citations: 53     Fields:    Translation:HumansCells
    19. Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Sfyroera G, Magotti P, Ivanciu L, Lupu C, Mollnes TE, Taylor FB, Kinasewitz G, Lambris JD, Lupu F. Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis. Blood. 2010 Aug 12; 116(6):1002-10. PMID: 20466856.
      Citations: 89     Fields:    Translation:Animals
    20. Popescu NI, Lupu C, Lupu F. Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure. Blood. 2010 Aug 12; 116(6):993-1001. PMID: 20448108.
      Citations: 62     Fields:    Translation:HumansCells
    21. Popescu NI, Lupu C, Lupu F. Role of PDI in regulating tissue factor: FVIIa activity. Thromb Res. 2010 Apr; 125 Suppl 1:S38-41. PMID: 20163832.
      Citations: 16     Fields:    Translation:HumansCells
    22. Tang H, Ivanciu L, Popescu N, Peer G, Hack E, Lupu C, Taylor FB, Lupu F. Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor. Am J Pathol. 2007 Sep; 171(3):1066-77. PMID: 17640967.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
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