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This is a "connection" page, showing publications co-authored by Ann West and Paul Cook.
Ann West
Connection Strength
2.319
Paul Cook
  1. Probing the chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae using site-directed mutagenesis. Arch Biochem Biophys. 2015 Oct 15; 584:98-106.
    View in: PubMed
    Score: 0.130
  2. Evidence for an induced conformational change in the catalytic mechanism of homoisocitrate dehydrogenase for Saccharomyces cerevisiae: Characterization of the D271N mutant enzyme. Arch Biochem Biophys. 2015 Oct 15; 584:20-7.
    View in: PubMed
    Score: 0.130
  3. Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae. Arch Biochem Biophys. 2012 Jun 01; 522(1):57-61.
    View in: PubMed
    Score: 0.103
  4. Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2012 Jan 31; 51(4):857-66.
    View in: PubMed
    Score: 0.101
  5. The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH. Arch Biochem Biophys. 2011 Sep 15; 513(2):71-80.
    View in: PubMed
    Score: 0.098
  6. Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction. Arch Biochem Biophys. 2011 Oct; 514(1-2):8-15.
    View in: PubMed
    Score: 0.098
  7. Kinetic and chemical mechanisms of homocitrate synthase from Thermus thermophilus. J Biol Chem. 2011 Aug 19; 286(33):29428-29439.
    View in: PubMed
    Score: 0.098
  8. Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts. J Biol Chem. 2010 Jul 02; 285(27):20756-68.
    View in: PubMed
    Score: 0.090
  9. Kinetic studies of the yeast His-Asp phosphorelay signaling pathway. Methods Enzymol. 2010; 471:59-75.
    View in: PubMed
    Score: 0.089
  10. Effects of osmolytes on the SLN1-YPD1-SSK1 phosphorelay system from Saccharomyces cerevisiae. Biochemistry. 2009 Aug 25; 48(33):8044-50.
    View in: PubMed
    Score: 0.086
  11. Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2009 Aug 04; 48(30):7305-12.
    View in: PubMed
    Score: 0.085
  12. Chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae. Biochemistry. 2009 Jun 30; 48(25):5899-907.
    View in: PubMed
    Score: 0.085
  13. Potassium is an activator of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2008 Oct 07; 47(40):10809-15.
    View in: PubMed
    Score: 0.080
  14. Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry. 2008 Jul 01; 47(26):6851-8.
    View in: PubMed
    Score: 0.079
  15. Overall kinetic mechanism of saccharopine dehydrogenase (L-glutamate forming) from Saccharomyces cerevisiae. Biochemistry. 2008 May 13; 47(19):5417-23.
    View in: PubMed
    Score: 0.078
  16. Chemical mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2008 Apr 01; 47(13):4169-80.
    View in: PubMed
    Score: 0.077
  17. Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2007 Nov 06; 46(44):12512-21.
    View in: PubMed
    Score: 0.075
  18. Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2007 Jun 26; 46(25):7625-36.
    View in: PubMed
    Score: 0.073
  19. A proposed proton shuttle mechanism for saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2007 Jan 23; 46(3):871-82.
    View in: PubMed
    Score: 0.072
  20. Complete kinetic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2007 Jan 23; 46(3):890-8.
    View in: PubMed
    Score: 0.072
  21. Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry. 2006 Oct 03; 45(39):12136-43.
    View in: PubMed
    Score: 0.070
  22. Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 2006 Oct 03; 45(39):12156-66.
    View in: PubMed
    Score: 0.070
  23. Crystal structure of the his-tagged saccharopine reductase from Saccharomyces cerevisiae at 1.7-A resolution. Cell Biochem Biophys. 2006; 46(1):17-26.
    View in: PubMed
    Score: 0.067
  24. The alpha-aminoadipate pathway for lysine biosynthesis in fungi. Cell Biochem Biophys. 2006; 46(1):43-64.
    View in: PubMed
    Score: 0.067
  25. Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. I. Kinetic studies. J Biol Chem. 2005 Sep 09; 280(36):31624-32.
    View in: PubMed
    Score: 0.064
  26. Kinetic analysis of YPD1-dependent phosphotransfer reactions in the yeast osmoregulatory phosphorelay system. Biochemistry. 2005 Jan 11; 44(1):377-86.
    View in: PubMed
    Score: 0.062
  27. Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. Biochemistry. 2004 Sep 21; 43(37):11790-5.
    View in: PubMed
    Score: 0.061
  28. Stabilization and characterization of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. Arch Biochem Biophys. 2004 Jan 15; 421(2):243-54.
    View in: PubMed
    Score: 0.058
Connection Strength

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