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Ira N Targoff

InstitutionUniversity of Oklahoma Health Sciences Center
AddressAAT 6400
800 Stanton L Young Blvd
Oklahoma City OK 73104
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    R29AI027181     (TARGOFF, IRA)Jul 1, 1989 - Aug 31, 1994
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Karasawa R, Yudoh K, Sato T, Tanaka M, Tamaki M, Sabbagh SE, O'Hanlon TP, Noroozi-Farhadi P, Targoff IN, Flegel WA, Mammen AL, Miller FW, Hicar MD, Rider LG, Jarvis JN. Association of Anti-HSC70 Autoantibodies with Cutaneous Ulceration and Severe Disease in Juvenile Dermatomyositis. Rheumatology (Oxford). 2021 Nov 13. PMID: 34791087.
      Citations:    Fields:    
    2. Kishi T, Warren-Hicks W, Bayat N, Targoff IN, Huber AM, Ward MM, Rider LG. Corticosteroid discontinuation, complete clinical response and remission in juvenile dermatomyositis. Rheumatology (Oxford). 2021 05 14; 60(5):2134-2145. PMID: 33067611.
      Citations:    Fields:    Translation:Humans
    3. Mamyrova G, Kishi T, Shi M, Targoff IN, Huber AM, Curiel RV, Miller FW, Rider LG. Anti-MDA5 autoantibodies associated with juvenile dermatomyositis constitute a distinct phenotype in North America. Rheumatology (Oxford). 2021 04 06; 60(4):1839-1849. PMID: 33140079.
      Citations: 6     Fields:    Translation:Humans
    4. Landon-Cardinal O, Baril-Dionne A, Hoa S, Meyer A, Leclair V, Bourré-Tessier J, Mansour AM, Zarka F, Makhzoum JP, Nehme J, Rich E, Goulet JR, Grodzicky T, Koenig M, Joyal F, Richard I, Hudson M, Targoff I, Satoh M, Fritzler MJ, Troyanov Y, Senécal JL. Recognising the spectrum of scleromyositis: HEp-2 ANA patterns allow identification of a novel clinical subset with anti-SMN autoantibodies. RMD Open. 2020 09; 6(2). PMID: 32892170.
    5. Kim H, Gunter-Rahman F, McGrath JA, Lee E, de Jesus AA, Targoff IN, Huang Y, O'Hanlon TP, Tsai WL, Gadina M, Miller FW, Goldbach-Mansky R, Rider LG. Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies. Arthritis Res Ther. 2020 04 06; 22(1):69. PMID: 32252809.
      Citations: 10     Fields:    Translation:Humans
    6. Meyer A, Troyanov Y, Drouin J, Oligny-Longpré G, Landon-Cardinal O, Hoa S, Hervier B, Bourré-Tessier J, Mansour AM, Hussein S, Morin V, Rich E, Goulet JR, Chartrand S, Hudson M, Nehme J, Makhzoum JP, Zarka F, Villeneuve E, Raynauld JP, Landry M, O'Ferrall EK, Ferreira J, Ellezam B, Karamchandani J, Larue S, Massie R, Isabelle C, Deschênes I, Leclair V, Couture H, Targoff IN, Fritzler MJ, Senécal JL. Statin-induced anti-HMGCR myopathy: successful therapeutic strategies for corticosteroid-free remission in 55 patients. Arthritis Res Ther. 2020 01 08; 22(1):5. PMID: 31915059.
      Citations: 18     Fields:    Translation:Humans
    7. Tsaltskan V, Aldous A, Serafi S, Yakovleva A, Sami H, Mamyrova G, Targoff IN, Schiffenbauer A, Miller FW, Simmens SJ, Curiel R, Jones OY, Rider LG. Long-term outcomes in Juvenile Myositis patients. Semin Arthritis Rheum. 2020 02; 50(1):149-155. PMID: 31303436.
      Citations: 4     Fields:    Translation:Humans
    8. Sabbagh S, Pinal-Fernandez I, Kishi T, Targoff IN, Miller FW, Rider LG, Mammen AL. Anti-Ro52 autoantibodies are associated with interstitial lung disease and more severe disease in patients with juvenile myositis. Ann Rheum Dis. 2019 07; 78(7):988-995. PMID: 31018961.
      Citations: 25     Fields:    Translation:Humans
    9. Trieu EP, Targoff IN. SDS-PAGE for 35S Immunoprecipitation and Immunoprecipitation Western Blotting. Methods Mol Biol. 2019; 1855:417-436. PMID: 30426436.
      Citations:    Fields:    Translation:HumansAnimals
    10. Mamyrova G, Kishi T, Targoff IN, Ehrlich A, Curiel RV, Rider LG. Features distinguishing clinically amyopathic juvenile dermatomyositis from juvenile dermatomyositis. Rheumatology (Oxford). 2018 11 01; 57(11):1956-1963. PMID: 30016492.
      Citations: 7     Fields:    Translation:Humans
    11. Kishi T, Bayat N, Ward MM, Huber AM, Wu L, Mamyrova G, Targoff IN, Warren-Hicks WJ, Miller FW, Rider LG. Medications received by patients with juvenile dermatomyositis. Semin Arthritis Rheum. 2018 12; 48(3):513-522. PMID: 29773230.
      Citations: 8     Fields:    Translation:Humans
    12. Schiffenbauer A, Faghihi-Kashani S, O'Hanlon TP, Flegel WA, Adams SD, Targoff IN, Oddis CV, Ytterberg SR, Aggarwal R, Christopher-Stine L, Shamim EA, Dellaripa PF, Danoff SK, Mammen AL, Miller FW. The effect of cigarette smoking on the clinical and serological phenotypes of polymyositis and dermatomyositis. Semin Arthritis Rheum. 2018 12; 48(3):504-512. PMID: 29703532.
      Citations: 10     Fields:    Translation:Humans
    13. Yeker RM, Pinal-Fernandez I, Kishi T, Pak K, Targoff IN, Miller FW, Rider LG, Mammen AL. Anti-NT5C1A autoantibodies are associated with more severe disease in patients with juvenile myositis. Ann Rheum Dis. 2018 05; 77(5):714-719. PMID: 29363513.
      Citations: 8     Fields:    Translation:Humans
    14. Hoa S, Troyanov Y, Fritzler MJ, Targoff IN, Chartrand S, Mansour AM, Rich E, Boudabbouz H, Bourré-Tessier J, Albert M, Goulet JR, Landry M, Senécal JL. Describing and expanding the clinical phenotype of anti-MDA5-associated rapidly progressive interstitial lung disease: case series of nine Canadian patients and literature review. Scand J Rheumatol. 2018 05; 47(3):210-224. PMID: 29065773.
      Citations: 12     Fields:    Translation:Humans
    15. Kishi T, Rider LG, Pak K, Barillas-Arias L, Henrickson M, McCarthy PL, Shaham B, Weiss PF, Horkayne-Szakaly I, Targoff IN, Miller FW, Mammen AL. Association of Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Autoantibodies With DRB1*07:01 and Severe Myositis in Juvenile Myositis Patients. Arthritis Care Res (Hoboken). 2017 07; 69(7):1088-1094. PMID: 28129483.
      Citations: 25     Fields:    Translation:Humans
    16. Troyanov Y, Landon-Cardinal O, Fritzler MJ, Ferreira J, Targoff IN, Rich E, Goulet M, Goulet JR, Bourré-Tessier J, Robitaille Y, Drouin J, Albert A, Senécal JL. Atorvastatin-induced necrotizing autoimmune myositis: An emerging dominant entity in patients with autoimmune myositis presenting with a pure polymyositis phenotype. Medicine (Baltimore). 2017 Jan; 96(3):e5694. PMID: 28099331.
      Citations: 12     Fields:    Translation:Humans
    17. Ibarra M, Rigsby C, Morgan GA, Sammet CL, Huang CC, Xu D, Targoff IN, Pachman LM. Monitoring change in volume of calcifications in juvenile idiopathic inflammatory myopathy: a pilot study using low dose computed tomography. Pediatr Rheumatol Online J. 2016 Nov 29; 14(1):64. PMID: 27894310.
      Citations: 2     Fields:    Translation:Humans
    18. Habers GE, Huber AM, Mamyrova G, Targoff IN, O'Hanlon TP, Adams S, Pandey JP, Boonacker C, van Brussel M, Miller FW, van Royen-Kerkhof A, Rider LG. Brief Report: Association of Myositis Autoantibodies, Clinical Features, and Environmental Exposures at Illness Onset With Disease Course in Juvenile Myositis. Arthritis Rheumatol. 2016 Mar; 68(3):761-8. PMID: 26474155.
      Citations: 18     Fields:    Translation:HumansPHPublic Health
    19. Trieu EP, Targoff IN. Immunoprecipitation: Western blot for proteins of low abundance. Methods Mol Biol. 2015; 1312:327-42. PMID: 26044015.
      Citations: 3     Fields:    Translation:Humans
    20. Troyanov Y, Targoff IN, Payette MP, Raynauld JP, Chartier S, Goulet JR, Bourré-Tessier J, Rich E, Grodzicky T, Fritzler MJ, Joyal F, Koenig M, Senécal JL. Redefining dermatomyositis: a description of new diagnostic criteria that differentiate pure dermatomyositis from overlap myositis with dermatomyositis features. Medicine (Baltimore). 2014 Nov; 93(24):318-332. PMID: 25500701.
      Citations: 28     Fields:    Translation:Humans
    21. Senécal JL, Isabelle C, Fritzler MJ, Targoff IN, Goldstein R, Gagné M, Raynauld JP, Joyal F, Troyanov Y, Dabauvalle MC. An autoimmune myositis-overlap syndrome associated with autoantibodies to nuclear pore complexes: description and long-term follow-up of the anti-Nup syndrome. Medicine (Baltimore). 2014 Nov; 93(24):383-394. PMID: 25500708.
      Citations: 7     Fields:    Translation:HumansCells
    22. Huber AM, Mamyrova G, Lachenbruch PA, Lee JA, Katz JD, Targoff IN, Miller FW, Rider LG. Early illness features associated with mortality in the juvenile idiopathic inflammatory myopathies. Arthritis Care Res (Hoboken). 2014 May; 66(5):732-40. PMID: 24151254.
      Citations: 26     Fields:    Translation:Humans
    23. Kurien BT, D'Sousa A, Bruner BF, Gross T, James JA, Targoff IN, Maier-Moore JS, Harley IT, Wang H, Scofield RH. Prolidase deficiency breaks tolerance to lupus-associated antigens. Int J Rheum Dis. 2013 Dec; 16(6):674-80. PMID: 24330273.
      Citations: 10     Fields:    Translation:Humans
    24. Mamyrova G, Katz JD, Jones RV, Targoff IN, Lachenbruch PA, Jones OY, Miller FW, Rider LG. Clinical and laboratory features distinguishing juvenile polymyositis and muscular dystrophy. Arthritis Care Res (Hoboken). 2013 Dec; 65(12):1969-75. PMID: 23925923.
      Citations: 4     Fields:    Translation:Humans
    25. Shah M, Targoff IN, Rice MM, Miller FW, Rider LG. Brief report: ultraviolet radiation exposure is associated with clinical and autoantibody phenotypes in juvenile myositis. Arthritis Rheum. 2013 Jul; 65(7):1934-41. PMID: 23658122.
      Citations: 26     Fields:    Translation:Humans
    26. Rider LG, Shah M, Mamyrova G, Huber AM, Rice MM, Targoff IN, Miller FW. The myositis autoantibody phenotypes of the juvenile idiopathic inflammatory myopathies. Medicine (Baltimore). 2013 Jul; 92(4):223-243. PMID: 23877355.
      Citations: 92     Fields:    Translation:Humans
    27. Shah M, Mamyrova G, Targoff IN, Huber AM, Malley JD, Rice MM, Miller FW, Rider LG. The clinical phenotypes of the juvenile idiopathic inflammatory myopathies. Medicine (Baltimore). 2013 Jan; 92(1):25-41. PMID: 23263716.
      Citations: 60     Fields:    Translation:Humans
    28. Trieu EP, Targoff IN. SDS-PAGE for ³5S immunoprecipitation and immunoprecipitation western blotting. Methods Mol Biol. 2012; 869:215-33. PMID: 22585489.
      Citations: 3     Fields:    Translation:HumansAnimals
    29. Gupta R, Wayangankar SA, Targoff IN, Hennebry TA. Clinical cardiac involvement in idiopathic inflammatory myopathies: a systematic review. Int J Cardiol. 2011 May 05; 148(3):261-70. PMID: 20826015.
      Citations: 33     Fields:    Translation:HumansAnimals
    30. Rider LG, Wu L, Mamyrova G, Targoff IN, Miller FW. Environmental factors preceding illness onset differ in phenotypes of the juvenile idiopathic inflammatory myopathies. Rheumatology (Oxford). 2010 Dec; 49(12):2381-90. PMID: 20802007.
      Citations: 18     Fields:    Translation:HumansPHPublic Health
    31. Wahlström J, Dengjel J, Winqvist O, Targoff I, Persson B, Duyar H, Rammensee HG, Eklund A, Weissert R, Grunewald J. Autoimmune T cell responses to antigenic peptides presented by bronchoalveolar lavage cell HLA-DR molecules in sarcoidosis. Clin Immunol. 2009 Dec; 133(3):353-63. PMID: 19786367.
      Citations: 24     Fields:    Translation:HumansCells
    32. Love LA, Weinberg CR, McConnaughey DR, Oddis CV, Medsger TA, Reveille JD, Arnett FC, Targoff IN, Miller FW. Ultraviolet radiation intensity predicts the relative distribution of dermatomyositis and anti-Mi-2 autoantibodies in women. Arthritis Rheum. 2009 Aug; 60(8):2499-504. PMID: 19644877.
      Citations: 43     Fields:    Translation:HumansPHPublic Health
    33. Trieu EP, Gross JK, Targoff IN. Immunoprecipitation-western blot for proteins of low abundance. Methods Mol Biol. 2009; 536:259-75. PMID: 19378065.
      Citations: 4     Fields:    Translation:HumansAnimals
    34. O'Hanlon TP, Rider LG, Schiffenbauer A, Targoff IN, Malley K, Pandey JP, Miller FW. Immunoglobulin gene polymorphisms are susceptibility factors in clinical and autoantibody subgroups of the idiopathic inflammatory myopathies. Arthritis Rheum. 2008 Oct; 58(10):3239-46. PMID: 18821675.
      Citations: 21     Fields:    Translation:Humans
    35. Targoff IN. Autoantibodies and their significance in myositis. Curr Rheumatol Rep. 2008 Aug; 10(4):333-40. PMID: 18662515.
      Citations: 23     Fields:    Translation:HumansAnimals
    36. Bingham A, Mamyrova G, Rother KI, Oral E, Cochran E, Premkumar A, Kleiner D, James-Newton L, Targoff IN, Pandey JP, Carrick DM, Sebring N, O'Hanlon TP, Ruiz-Hidalgo M, Turner M, Gordon LB, Laborda J, Bauer SR, Blackshear PJ, Imundo L, Miller FW, Rider LG. Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity. Medicine (Baltimore). 2008 Mar; 87(2):70-86. PMID: 18344805.
      Citations: 48     Fields:    Translation:Humans
    37. Vegosen LJ, Weinberg CR, O'Hanlon TP, Targoff IN, Miller FW, Rider LG. Seasonal birth patterns in myositis subgroups suggest an etiologic role of early environmental exposures. Arthritis Rheum. 2007 Aug; 56(8):2719-28. PMID: 17665425.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    38. Hirakata M, Suwa A, Takada T, Sato S, Nagai S, Genth E, Song YW, Mimori T, Targoff IN. Clinical and immunogenetic features of patients with autoantibodies to asparaginyl-transfer RNA synthetase. Arthritis Rheum. 2007 Apr; 56(4):1295-303. PMID: 17393393.
      Citations: 24     Fields:    Translation:HumansCells
    39. Koenig M, Fritzler MJ, Targoff IN, Troyanov Y, Senécal JL. Heterogeneity of autoantibodies in 100 patients with autoimmune myositis: insights into clinical features and outcomes. Arthritis Res Ther. 2007; 9(4):R78. PMID: 17688695.
      Citations: 58     Fields:    Translation:Humans
    40. O'Hanlon TP, Rider LG, Mamyrova G, Targoff IN, Arnett FC, Reveille JD, Carrington M, Gao X, Oddis CV, Morel PA, Malley JD, Malley K, Shamim EA, Chanock SJ, Foster CB, Bunch T, Reed AM, Love LA, Miller FW. HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies. Arthritis Rheum. 2006 Nov; 54(11):3670-81. PMID: 17075818.
      Citations: 29     Fields:    Translation:HumansCells
    41. Targoff IN, Mamyrova G, Trieu EP, Perurena O, Koneru B, O'Hanlon TP, Miller FW, Rider LG. A novel autoantibody to a 155-kd protein is associated with dermatomyositis. Arthritis Rheum. 2006 Nov; 54(11):3682-9. PMID: 17075819.
      Citations: 119     Fields:    Translation:HumansPHPublic Health
    42. Targoff IN. Myositis specific autoantibodies. Curr Rheumatol Rep. 2006 Jun; 8(3):196-203. PMID: 16901077.
      Citations: 21     Fields:    Translation:Humans
    43. O'Hanlon TP, Carrick DM, Targoff IN, Arnett FC, Reveille JD, Carrington M, Gao X, Oddis CV, Morel PA, Malley JD, Malley K, Shamim EA, Rider LG, Chanock SJ, Foster CB, Bunch T, Blackshear PJ, Plotz PH, Love LA, Miller FW. Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies. Medicine (Baltimore). 2006 Mar; 85(2):111-127. PMID: 16609350.
      Citations: 50     Fields:    Translation:HumansCells
    44. Sarkar K, Weinberg CR, Oddis CV, Medsger TA, Plotz PH, Reveille JD, Arnett FC, Targoff IN, Genth E, Love LA, Miller FW. Seasonal influence on the onset of idiopathic inflammatory myopathies in serologically defined groups. Arthritis Rheum. 2005 Aug; 52(8):2433-8. PMID: 16052581.
      Citations: 15     Fields:    Translation:Humans
    45. Troyanov Y, Targoff IN, Tremblay JL, Goulet JR, Raymond Y, Senécal JL. Novel classification of idiopathic inflammatory myopathies based on overlap syndrome features and autoantibodies: analysis of 100 French Canadian patients. Medicine (Baltimore). 2005 Jul; 84(4):231-249. PMID: 16010208.
      Citations: 117     Fields:    Translation:Humans
    46. O'Hanlon T, Koneru B, Bayat E, Love L, Targoff I, Malley J, Malley K, Miller F. Immunogenetic differences between Caucasian women with and those without silicone implants in whom myositis develops. Arthritis Rheum. 2004 Nov; 50(11):3646-50. PMID: 15529361.
      Citations: 7     Fields:    Translation:Humans
    47. Okada S, Weatherhead E, Targoff IN, Wesley R, Miller FW. Global surface ultraviolet radiation intensity may modulate the clinical and immunologic expression of autoimmune muscle disease. Arthritis Rheum. 2003 Aug; 48(8):2285-93. PMID: 12905483.
      Citations: 43     Fields:    Translation:HumansPHPublic Health
    48. Targoff IN. Laboratory testing in the diagnosis and management of idiopathic inflammatory myopathies. Rheum Dis Clin North Am. 2002 Nov; 28(4):859-90, viii. PMID: 12506776.
      Citations: 37     Fields:    Translation:Humans
    49. Targoff IN. Idiopathic inflammatory myopathy: autoantibody update. Curr Rheumatol Rep. 2002 Oct; 4(5):434-41. PMID: 12217249.
      Citations: 14     Fields:    Translation:Humans
    50. Shamim EA, Rider LG, Pandey JP, O'Hanlon TP, Jara LJ, Samayoa EA, Burgos-Vargas R, Vazquez-Mellado J, Alcocer-Varela J, Salazar-Paramo M, Kutzbach AG, Malley JD, Targoff IN, Garcia-De la Torre I, Miller FW. Differences in idiopathic inflammatory myopathy phenotypes and genotypes between Mesoamerican Mestizos and North American Caucasians: ethnogeographic influences in the genetics and clinical expression of myositis. Arthritis Rheum. 2002 Jul; 46(7):1885-93. PMID: 12124873.
      Citations: 26     Fields:    Translation:Humans
    51. Targoff IN. Update on myositis-specific and myositis-associated autoantibodies. Curr Opin Rheumatol. 2000 Nov; 12(6):475-81. PMID: 11092195.
      Citations: 31     Fields:    Translation:Humans
    52. D'Cruz D, Keser G, Khamashta MA, Direskeneli H, Targoff IN, Miller F, Hughes GR. Antiendothelial cell antibodies in inflammatory myopathies: distribution among clinical and serologic groups and association with interstitial lung disease. J Rheumatol. 2000 Jan; 27(1):161-4. PMID: 10648033.
      Citations: 3     Fields:    Translation:Humans
    53. Lee LA, Walsh P, Prater CA, Su LJ, Marchbank A, Egbert TB, Dellavalle RP, Targoff IN, Kaufman KM, Chorzelski TP, Jablonska S. Characterization of an autoantigen associated with chronic ulcerative stomatitis: the CUSP autoantigen is a member of the p53 family. J Invest Dermatol. 1999 Aug; 113(2):146-51. PMID: 10469295.
      Citations: 6     Fields:    Translation:HumansCells
    54. Rider LG, Shamim E, Okada S, Pandey JP, Targoff IN, O'Hanlon TP, Kim HA, Lim YS, Han H, Song YW, Miller FW. Genetic risk and protective factors for idiopathic inflammatory myopathy in Koreans and American whites: a tale of two loci. Arthritis Rheum. 1999 Jun; 42(6):1285-90. PMID: 10366124.
      Citations: 16     Fields:    Translation:Humans
    55. Frank MB, McCubbin V, Trieu E, Wu Y, Isenberg DA, Targoff IN. The association of anti-Ro52 autoantibodies with myositis and scleroderma autoantibodies. J Autoimmun. 1999 Mar; 12(2):137-42. PMID: 10047434.
      Citations: 23     Fields:    Translation:Humans
    56. Hirakata M, Suwa A, Nagai S, Kron MA, Trieu EP, Mimori T, Akizuki M, Targoff IN. Anti-KS: identification of autoantibodies to asparaginyl-transfer RNA synthetase associated with interstitial lung disease. J Immunol. 1999 Feb 15; 162(4):2315-20. PMID: 9973509.
      Citations: 39     Fields:    Translation:HumansCells
    57. García-Lozano JR, González-Escribano MF, Rodríguez R, Rodriguez-Sanchez JL, Targoff IN, Wichmann I, Núñez-Roldán A. Detection of anti-PL-12 autoantibodies by ELISA using a recombinant antigen; study of the immunoreactive region. Clin Exp Immunol. 1998 Nov; 114(2):161-5. PMID: 9822271.
      Citations: 2     Fields:    Translation:HumansCells
    58. Rider LG, Gurley RC, Pandey JP, Garcia de la Torre I, Kalovidouris AE, O'Hanlon TP, Love LA, Hennekam RC, Baumbach LL, Neville HE, Garcia CA, Klingman J, Gibbs M, Weisman MH, Targoff IN, Miller FW. Clinical, serologic, and immunogenetic features of familial idiopathic inflammatory myopathy. Arthritis Rheum. 1998 Apr; 41(4):710-9. PMID: 9550481.
      Citations: 11     Fields:    Translation:Humans
    59. Targoff IN, Miller FW, Medsger TA, Oddis CV. Classification criteria for the idiopathic inflammatory myopathies. Curr Opin Rheumatol. 1997 Nov; 9(6):527-35. PMID: 9375282.
      Citations: 54     Fields:    Translation:Humans
    60. Salojin KV, Bordron A, Nassonov EL, Shtutman VZ, Guseva NG, Baranov AA, Targoff IN, Youinou P. Anti-endothelial cell antibody, thrombomodulin, and von Willebrand factor in idiopathic inflammatory myopathies. Clin Diagn Lab Immunol. 1997 Sep; 4(5):519-21. PMID: 9302198.
      Citations: 1     Fields:    Translation:Humans
    61. Koscec M, Koren E, Wolfson-Reichlin M, Fugate RD, Trieu E, Targoff IN, Reichlin M. Autoantibodies to ribosomal P proteins penetrate into live hepatocytes and cause cellular dysfunction in culture. J Immunol. 1997 Aug 15; 159(4):2033-41. PMID: 9257871.
      Citations: 30     Fields:    Translation:AnimalsCells
    62. Hausmanowa-Petrusewicz I, Kowalska-Oledzka E, Miller FW, Jarzabek-Chorzelska M, Targoff IN, Blaszczyk-Kostanecka M, Jablonska S. Clinical, serologic, and immunogenetic features in Polish patients with idiopathic inflammatory myopathies. Arthritis Rheum. 1997 Jul; 40(7):1257-66. PMID: 9214426.
      Citations: 37     Fields:    Translation:Humans
    63. Okano Y, Targoff IN, Oddis CV, Fujii T, Kuwana M, Tsuzaka K, Hirakata M, Mimori T, Craft J, Medsger TA. Anti-U5 small nuclear ribonucleoprotein (snRNP) antibodies: a rare anti-U snRNP specificity. Clin Immunol Immunopathol. 1996 Oct; 81(1):41-7. PMID: 8808640.
      Citations: 8     Fields:    Translation:HumansCells
    64. Schnitz W, Taylor-Albert E, Targoff IN, Reichlin M, Scofield RH. Anti-PM/Scl autoantibodies in patients without clinical polymyositis or scleroderma. J Rheumatol. 1996 Oct; 23(10):1729-33. PMID: 8895149.
      Citations: 6     Fields:    Translation:Humans
    65. Feldman BM, Reichlin M, Laxer RM, Targoff IN, Stein LD, Silverman ED. Clinical significance of specific autoantibodies in juvenile dermatomyositis. J Rheumatol. 1996 Oct; 23(10):1794-7. PMID: 8895161.
      Citations: 11     Fields:    Translation:Humans
    66. Seelig HP, Renz M, Targoff IN, Ge Q, Frank MB. Two forms of the major antigenic protein of the dermatomyositis-specific Mi-2 autoantigen. Arthritis Rheum. 1996 Oct; 39(10):1769-71. PMID: 8843877.
      Citations: 19     Fields:    Translation:HumansCells
    67. Arnett FC, Targoff IN, Mimori T, Goldstein R, Warner NB, Reveille JD. Interrelationship of major histocompatibility complex class II alleles and autoantibodies in four ethnic groups with various forms of myositis. Arthritis Rheum. 1996 Sep; 39(9):1507-18. PMID: 8814062.
      Citations: 45     Fields:    Translation:Humans
    68. Ge Q, Wu Y, James JA, Targoff IN. Epitope analysis of the major reactive region of the 100-kd protein of PM-Scl autoantigen. Arthritis Rheum. 1996 Sep; 39(9):1588-95. PMID: 8814071.
      Citations: 3     Fields:    Translation:HumansCells
    69. Nichols RC, Blinder J, Pai SI, Ge Q, Targoff IN, Plotz PH, Liu P. Assignment of two human autoantigen genes-isoleucyl-tRNA synthetase locates to 9q21 and lysyl-tRNA synthetase locates to 16q23-q24. Genomics. 1996 Aug 15; 36(1):210-3. PMID: 8812440.
      Citations: 1     Fields:    Translation:HumansCells
    70. Friedman AW, Targoff IN, Arnett FC. Interstitial lung disease with autoantibodies against aminoacyl-tRNA synthetases in the absence of clinically apparent myositis. Semin Arthritis Rheum. 1996 Aug; 26(1):459-67. PMID: 8870113.
      Citations: 39     Fields:    Translation:HumansCells
    71. Gelpí C, Kanterewicz E, Gratacos J, Targoff IN, Rodríguez-Sánchez JL. Coexistence of two antisynthetases in a patient with the antisynthetase syndrome. Arthritis Rheum. 1996 Apr; 39(4):692-7. PMID: 8630123.
      Citations: 11     Fields:    Translation:Humans
    72. Hirakata M, Suwa A, Takeda Y, Matsuoka Y, Irimajiri S, Targoff IN, Hardin JA, Craft J. Autoantibodies to glycyl-transfer RNA synthetase in myositis. Association with dermatomyositis and immunologic heterogeneity. Arthritis Rheum. 1996 Jan; 39(1):146-51. PMID: 8546723.
      Citations: 7     Fields:    Translation:HumansCells
    73. Nichols RC, Pai SI, Ge Q, Targoff IN, Plotz PH, Liu P. Localization of two human autoantigen genes by PCR screening and in situ hybridization--glycyl-tRNA synthetase locates to 7p15 and alanyl-tRNA synthetase locates to 16q22. Genomics. 1995 Nov 01; 30(1):131-2. PMID: 8595897.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    74. Ge Q, Nilasena DS, O'Brien CA, Frank MB, Targoff IN. Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen. J Clin Invest. 1995 Oct; 96(4):1730-7. PMID: 7560064.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    75. Kaufman LD, Varga J, Gomez-Reino JJ, Jimenez S, Targoff IN. Autoantibodies in sera from patients with L-tryptophan-associated eosinophilia-myalgia syndrome. Demonstration of unique antigen-antibody specificities. Clin Immunol Immunopathol. 1995 Aug; 76(2):115-9. PMID: 7542184.
      Citations:    Fields:    Translation:Humans
    76. Plotz PH, Rider LG, Targoff IN, Raben N, O'Hanlon TP, Miller FW. NIH conference. Myositis: immunologic contributions to understanding cause, pathogenesis, and therapy. Ann Intern Med. 1995 May 01; 122(9):715-24. PMID: 7702234.
      Citations: 29     Fields:    Translation:Humans
    77. Chmiel JF, Wessel HU, Targoff IN, Pachman LM. Pulmonary fibrosis and myositis in a child with anti-Jo-1 antibody. J Rheumatol. 1995 Apr; 22(4):762-5. PMID: 7791178.
      Citations:    Fields:    Translation:Humans
    78. Nilasena DS, Trieu EP, Targoff IN. Analysis of the Mi-2 autoantigen of dermatomyositis. Arthritis Rheum. 1995 Jan; 38(1):123-8. PMID: 7818561.
      Citations: 12     Fields:    Translation:Humans
    79. Ge Q, Trieu EP, Targoff IN. Primary structure and functional expression of human Glycyl-tRNA synthetase, an autoantigen in myositis. J Biol Chem. 1994 Nov 18; 269(46):28790-7. PMID: 7961834.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    80. Targoff IN. Immune manifestations of inflammatory muscle disease. Rheum Dis Clin North Am. 1994 Nov; 20(4):857-80. PMID: 7855326.
      Citations: 11     Fields:    Translation:Humans
    81. Ge Q, Wu Y, Trieu EP, Targoff IN. Analysis of the specificity of anti-PM-Scl autoantibodies. Arthritis Rheum. 1994 Oct; 37(10):1445-52. PMID: 7945469.
      Citations: 5     Fields:    Translation:Humans
    82. Rider LG, Miller FW, Targoff IN, Sherry DD, Samayoa E, Lindahl M, Wener MH, Pachman LM, Plotz PH. A broadened spectrum of juvenile myositis. Myositis-specific autoantibodies in children. Arthritis Rheum. 1994 Oct; 37(10):1534-8. PMID: 7945480.
      Citations: 20     Fields:    Translation:Humans
    83. Gelpí C, Martinez MA, Vidal S, Targoff IN, Rodriguez-Sanchez JL. Autoantibodies to a transfer RNA-associated protein in a murine model of chronic graft versus host disease. J Immunol. 1994 Feb 15; 152(4):1989-99. PMID: 8120403.
      Citations: 7     Fields:    Translation:AnimalsCells
    84. Targoff IN, Trieu EP, Miller FW. Reaction of anti-OJ autoantibodies with components of the multi-enzyme complex of aminoacyl-tRNA synthetases in addition to isoleucyl-tRNA synthetase. J Clin Invest. 1993 Jun; 91(6):2556-64. PMID: 8514867.
      Citations: 40     Fields:    Translation:Humans
    85. Joffe MM, Love LA, Leff RL, Fraser DD, Targoff IN, Hicks JE, Plotz PH, Miller FW. Drug therapy of the idiopathic inflammatory myopathies: predictors of response to prednisone, azathioprine, and methotrexate and a comparison of their efficacy. Am J Med. 1993 Apr; 94(4):379-87. PMID: 8386437.
      Citations: 59     Fields:    Translation:HumansCells
    86. Targoff IN. Humoral immunity in polymyositis/dermatomyositis. J Invest Dermatol. 1993 Jan; 100(1):116S-123S. PMID: 8423380.
      Citations: 21     Fields:    Translation:HumansCells
    87. Ge Q, Frank MB, O'Brien C, Targoff IN. Cloning of a complementary DNA coding for the 100-kD antigenic protein of the PM-Scl autoantigen. J Clin Invest. 1992 Aug; 90(2):559-70. PMID: 1644924.
      Citations: 14     Fields:    Translation:HumansCells
    88. Targoff IN, Trieu EP, Plotz PH, Miller FW. Antibodies to glycyl-transfer RNA synthetase in patients with myositis and interstitial lung disease. Arthritis Rheum. 1992 Jul; 35(7):821-30. PMID: 1622421.
      Citations: 24     Fields:    Translation:Humans
    89. Targoff IN. Autoantibodies in polymyositis. Rheum Dis Clin North Am. 1992 May; 18(2):455-82. PMID: 1378227.
      Citations: 22     Fields:    Translation:HumansCells
    90. Sontheimer RD, McCauliffe DP, Zappi E, Targoff I. Antinuclear antibodies: clinical correlations and biologic significance. Adv Dermatol. 1992; 7:3-52; discussion 53. PMID: 1371222.
      Citations: 4     Fields:    Translation:HumansCells
    91. Love LA, Leff RL, Fraser DD, Targoff IN, Dalakas M, Plotz PH, Miller FW. A new approach to the classification of idiopathic inflammatory myopathy: myositis-specific autoantibodies define useful homogeneous patient groups. Medicine (Baltimore). 1991 Nov; 70(6):360-74. PMID: 1659647.
      Citations: 207     Fields:    Translation:HumansCells
    92. Leff RL, Burgess SH, Miller FW, Love LA, Targoff IN, Dalakas MC, Joffe MM, Plotz PH. Distinct seasonal patterns in the onset of adult idiopathic inflammatory myopathy in patients with anti-Jo-1 and anti-signal recognition particle autoantibodies. Arthritis Rheum. 1991 Nov; 34(11):1391-6. PMID: 1953817.
      Citations: 22     Fields:    Translation:Humans
    93. Codding C, Targoff IN, McCarty GA. Aseptic meningitis in association with diclofenac treatment in a patient with systemic lupus erythematosus. Arthritis Rheum. 1991 Oct; 34(10):1340-1. PMID: 1930326.
      Citations: 2     Fields:    Translation:Humans
    94. Targoff IN. Polymyositis. Immunol Ser. 1991; 54:201-46. PMID: 1954276.
      Citations:    Fields:    Translation:HumansAnimals
    95. Duncan AG, Richardson JB, Klein JB, Targoff IN, Woodcock TM, Callen JP. Clinical, serologic, and immunogenetic studies in patients with dermatomyositis. Acta Derm Venereol. 1991; 71(4):312-6. PMID: 1681647.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    96. Targoff IN. Immune mechanisms in myositis. Curr Opin Rheumatol. 1990 Dec; 2(6):882-8. PMID: 2083152.
      Citations: 1     Fields:    Translation:Humans
    97. Targoff IN, Johnson AE, Miller FW. Antibody to signal recognition particle in polymyositis. Arthritis Rheum. 1990 Sep; 33(9):1361-70. PMID: 2403400.
      Citations: 68     Fields:    Translation:HumansCells
    98. Goldstein R, Duvic M, Targoff IN, Reichlin M, McMenemy AM, Reveille JD, Warner NB, Pollack MS, Arnett FC. HLA-D region genes associated with autoantibody responses to histidyl-transfer RNA synthetase (Jo-1) and other translation-related factors in myositis. Arthritis Rheum. 1990 Aug; 33(8):1240-8. PMID: 1975177.
      Citations: 10     Fields:    Translation:HumansCells
    99. Targoff IN. Diagnosis and treatment of polymyositis and dermatomyositis. Compr Ther. 1990 Apr; 16(4):16-24. PMID: 2185913.
      Citations:    Fields:    Translation:Humans
    100. Targoff IN. Autoantibodies to aminoacyl-transfer RNA synthetases for isoleucine and glycine. Two additional synthetases are antigenic in myositis. J Immunol. 1990 Mar 01; 144(5):1737-43. PMID: 2307838.
      Citations: 38     Fields:    Translation:Humans
    101. Moulds JM, Rolih C, Goldstein R, Whittington KF, Warner NB, Targoff IN, Reichlin M, Arnett FC. C4 null genes in American whites and blacks with myositis. J Rheumatol. 1990 Mar; 17(3):331-4. PMID: 2332854.
      Citations: 3     Fields:    Translation:Humans
    102. Targoff IN, Arnett FC. Clinical manifestations in patients with antibody to PL-12 antigen (alanyl-tRNA synthetase). Am J Med. 1990 Mar; 88(3):241-51. PMID: 2178410.
      Citations: 25     Fields:    Translation:Humans
    103. Targoff IN. Immunologic aspects of myositis. Curr Opin Rheumatol. 1989 Dec; 1(4):432-42. PMID: 2562008.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    104. Targoff IN, Arnett FC, Berman L, O'Brien C, Reichlin M. Anti-KJ: a new antibody associated with the syndrome of polymyositis and interstitial lung disease. J Clin Invest. 1989 Jul; 84(1):162-72. PMID: 2661587.
      Citations: 8     Fields:    Translation:Humans
    105. Targoff IN, Reichlin M. Humoral immunity in polymyositis and dermatomyositis. Mt Sinai J Med. 1988 Nov; 55(6):487-93. PMID: 3068537.
      Citations:    Fields:    Translation:Humans
    106. Targoff IN, Arnett FC, Reichlin M. Antibody to threonyl-transfer RNA synthetase in myositis sera. Arthritis Rheum. 1988 Apr; 31(4):515-24. PMID: 3128989.
      Citations: 9     Fields:    Translation:HumansCells
    107. Targoff IN. Laboratory manifestations of polymyositis/dermatomyositis. Clin Dermatol. 1988 Apr-Jun; 6(2):76-92. PMID: 3293746.
      Citations: 5     Fields:    Translation:Humans
    108. Targoff IN, Reichlin M. Measurement of antibody to Jo-1 by ELISA and comparison to enzyme inhibitory activity. J Immunol. 1987 May 01; 138(9):2874-82. PMID: 3553328.
      Citations: 13     Fields:    Translation:HumansCells
    109. Targoff IN, Reichlin M. The association between Mi-2 antibodies and dermatomyositis. Arthritis Rheum. 1985 Jul; 28(7):796-803. PMID: 2409985.
      Citations: 57     Fields:    Translation:Humans
    110. Targoff IN, Reichlin M. Nucleolar localization of the PM-Scl antigen. Arthritis Rheum. 1985 Feb; 28(2):226-30. PMID: 3918546.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    111. Reichlin M, Maddison PJ, Targoff I, Bunch T, Arnett F, Sharp G, Treadwell E, Tan EM. Antibodies to a nuclear/nucleolar antigen in patients with polymyositis overlap syndromes. J Clin Immunol. 1984 Jan; 4(1):40-4. PMID: 6699138.
      Citations: 33     Fields:    Translation:HumansCells
    112. Targoff IN, Raghu G, Reichlin M. Antibodies to Mi-1 in SLE: relationship to other precipitins and reaction with bovine immunoglobulin. Clin Exp Immunol. 1983 Jul; 53(1):76-82. PMID: 6409478.
      Citations:    Fields:    Translation:Humans
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