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Allan F Wiechmann

TitleProf,Asoc
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentCell Biology
AddressBMSB 553
940 Stanton L Young Blvd
Oklahoma City OK 73104
Phone405/271-8001
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    F32EY005859     (WIECHMANN, ALLAN F)Oct 21, 1985
    NIH
    THE ROLE OF MELATONIN IN RETINAL METABOLISM
    Role: Principal Investigator

    R29EY008006     (WIECHMANN, ALLAN F)May 1, 1988 - Apr 30, 1993
    NIH
    REGULATION AND FUNCTION OF MELATONIN IN THE RETINA
    Role: Principal Investigator

    R01EY010081     (WIECHMANN, ALLAN F)May 1, 1993 - Apr 30, 2000
    NIH
    EXPRESSION OF RECOVERIN IN THE RETINA
    Role: Principal Investigator

    R03EY013686     (WIECHMANN, ALLAN F)Feb 7, 2002 - Aug 31, 2006
    NIH
    Retinal Circadian Signaling in a Transgenic Model
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wiechmann AF, Martin TA, Horb ME. CRISPR/Cas9 mediated mutation of the mtnr1a melatonin receptor gene causes rod photoreceptor degeneration in developing Xenopus tropicalis. Sci Rep. 2020 08 13; 10(1):13757. PMID: 32792587.
      Citations:    Fields:    Translation:AnimalsCells
    2. Harper AR, Wiechmann AF, Moiseyev G, Ma JX, Summers JA. Identification of active retinaldehyde dehydrogenase isoforms in the postnatal human eye. PLoS One. 2015; 10(3):e0122008. PMID: 25793304.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    3. Wiechmann AF, Ceresa BP, Howard EW. Diurnal variation of tight junction integrity associates inversely with matrix metalloproteinase expression in Xenopus laevis corneal epithelium: implications for circadian regulation of homeostatic surface cell desquamation. PLoS One. 2014; 9(11):e113810. PMID: 25412440.
      Citations: 4     Fields:    Translation:AnimalsCells
    4. Wiechmann AF, Sherry DM. Role of melatonin and its receptors in the vertebrate retina. Int Rev Cell Mol Biol. 2013; 300:211-42. PMID: 23273863.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    5. Wiechmann AF, Sherry DM. Melatonin receptors are anatomically organized to modulate transmission specifically to cone pathways in the retina of Xenopus laevis. J Comp Neurol. 2012 Apr 15; 520(6):1115-27. PMID: 22020534.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Fung KM, Hassell LA, Talbert ML, Wiechmann AF, Chaser BE, Ramey J. Whole slide images and digital media in pathology education, testing, and practice: the Oklahoma experience. Anal Cell Pathol (Amst). 2012; 35(1):37-40. PMID: 21965282.
      Citations: 5     Fields:    Translation:Humans
    7. Rada JA, Wiechmann AF, Hollaway LR, Baggenstoss BA, Weigel PH. Increased hyaluronan synthase-2 mRNA expression and hyaluronan accumulation with choroidal thickening: response during recovery from induced myopia. Invest Ophthalmol Vis Sci. 2010 Dec; 51(12):6172-9. PMID: 20574026.
      Citations: 10     Fields:    Translation:Animals
    8. Huang Z, Anderson RE, Cao W, Wiechmann AF, Rajala RV. Light-induced tyrosine phosphorylation of rod outer segment membrane proteins regulate the translocation, membrane binding and activation of type II a phosphatidylinositol-5-phosphate 4-kinase. Neurochem Res. 2011 Apr; 36(4):627-35. PMID: 20204506.
      Citations: 5     Fields:    Translation:AnimalsCells
    9. Wiechmann AF, Hollaway LR, Rada JA. Melatonin receptor expression in Xenopus laevis surface corneal epithelium: diurnal rhythm of lateral membrane localization. Mol Vis. 2009 Nov 17; 15:2384-403. PMID: 19936310.
      Citations: 3     Fields:    Translation:AnimalsCells
    10. Rada JA, Wiechmann AF. Ocular expression of avian thymic hormone: changes during the recovery from induced myopia. Mol Vis. 2009; 15:778-92. PMID: 19390653.
      Citations: 16     Fields:    Translation:AnimalsCells
    11. Li G, Rajala A, Wiechmann AF, Anderson RE, Rajala RV. Activation and membrane binding of retinal protein kinase Balpha/Akt1 is regulated through light-dependent generation of phosphoinositides. J Neurochem. 2008 Dec; 107(5):1382-97. PMID: 18823366.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    12. Plafker KS, Farjo KM, Wiechmann AF, Plafker SM. The human ubiquitin conjugating enzyme, UBE2E3, is required for proliferation of retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2008 Dec; 49(12):5611-8. PMID: 18614808.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    13. Wiechmann AF, Summers JA. Circadian rhythms in the eye: the physiological significance of melatonin receptors in ocular tissues. Prog Retin Eye Res. 2008 Mar; 27(2):137-60. PMID: 18316227.
      Citations: 35     Fields:    Translation:HumansAnimals
    14. Wiechmann AF, Chignell CF, Roberts JE. Influence of dietary melatonin on photoreceptor survival in the rat retina: an ocular toxicity study. Exp Eye Res. 2008 Feb; 86(2):241-50. PMID: 18078931.
      Citations: 5     Fields:    Translation:AnimalsCellsPHPublic Health
    15. Rada JA, Wiechmann AF. Melatonin receptors in chick ocular tissues: implications for a role of melatonin in ocular growth regulation. Invest Ophthalmol Vis Sci. 2006 Jan; 47(1):25-33. PMID: 16384940.
      Citations: 26     Fields:    Translation:Animals
    16. Prada C, Udin SB, Wiechmann AF, Zhdanova IV. Stimulation of melatonin receptors decreases calcium levels in xenopus tectal cells by activating GABA(C) receptors. J Neurophysiol. 2005 Aug; 94(2):968-78. PMID: 15817645.
      Citations: 7     Fields:    Translation:AnimalsCells
    17. Wiechmann AF, Udin SB, Summers Rada JA. Localization of Mel1b melatonin receptor-like immunoreactivity in ocular tissues of Xenopus laevis. Exp Eye Res. 2004 Oct; 79(4):585-94. PMID: 15381042.
      Citations: 13     Fields:    Translation:Animals
    18. Wiechmann AF, Vrieze MJ, Dighe R, Hu Y. Direct modulation of rod photoreceptor responsiveness through a Mel(1c) melatonin receptor in transgenic Xenopus laevis retina. Invest Ophthalmol Vis Sci. 2003 Oct; 44(10):4522-31. PMID: 14507901.
      Citations: 15     Fields:    Translation:AnimalsCells
    19. Wiechmann AF, Rada JA. Melatonin receptor expression in the cornea and sclera. Exp Eye Res. 2003 Aug; 77(2):219-25. PMID: 12873453.
      Citations: 9     Fields:    Translation:Animals
    20. Wiechmann AF, Vrieze MJ, Wirsig-Wiechmann CR. Differential distribution of melatonin receptors in the pituitary gland of Xenopus laevis. Anat Embryol (Berl). 2003 Mar; 206(4):291-9. PMID: 12649727.
      Citations: 2     Fields:    Translation:Animals
    21. Wiechmann A, Howard E. Functional analysis of the human recoverin gene promoter. Curr Eye Res. 2003 Jan; 26(1):25-32. PMID: 12789533.
      Citations: 1     Fields:    Translation:HumansCells
    22. Wiechmann AF. Differential distribution of Mel(1a) and Mel(1c) melatonin receptors in Xenopus laevis retina. Exp Eye Res. 2003 Jan; 76(1):99-106. PMID: 12589779.
      Citations: 6     Fields:    Translation:AnimalsCells
    23. Wiechmann AF. Regulation of gene expression by melatonin: a microarray survey of the rat retina. J Pineal Res. 2002 Oct; 33(3):178-85. PMID: 12220334.
      Citations: 1     Fields:    Translation:AnimalsCells
    24. Wirsig-Wiechmann CR, Wiechmann AF. Vole retina is a target for gonadotropin-releasing hormone. Brain Res. 2002 Sep 20; 950(1-2):210-7. PMID: 12231246.
      Citations: 7     Fields:    Translation:AnimalsCells
    25. Wiechmann AF, Komori N, Matsumoto H. Melatonin induces alterations in protein expression in the Xenopus laevis retina. J Pineal Res. 2002 May; 32(4):270-4. PMID: 11982798.
      Citations:    Fields:    Translation:Animals
    26. Thompson AM, Wiechmann AF. 5-HT(1A) receptor subtype mRNA expression in cochlear nucleus. Hear Res. 2002 Feb; 164(1-2):77-81. PMID: 11950527.
      Citations: 3     Fields:    Translation:AnimalsCells
    27. Wirsig-Wiechmann CR, Wiechmann AF, Eisthen HL. What defines the nervus terminalis? Neurochemical, developmental, and anatomical criteria. Prog Brain Res. 2002; 141:45-58. PMID: 12508560.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    28. Wirsig-Wiechmann CR, Wiechmann AF. The prairie vole vomeronasal organ is a target for gonadotropin-releasing hormone. Chem Senses. 2001 Nov; 26(9):1193-202. PMID: 11705805.
      Citations: 4     Fields:    Translation:AnimalsCells
    29. Wiechmann AF, Wirsig-Wiechmann CR. Melatonin receptor mRNA and protein expression in Xenopus laevis nonpigmented ciliary epithelial cells. Exp Eye Res. 2001 Nov; 73(5):617-23. PMID: 11747362.
      Citations: 8     Fields:    Translation:AnimalsCells
    30. Wiechmann AF, Wirsig-Wiechmann CR. Multiple cell targets for melatonin action in Xenopus laevis retina: distribution of melatonin receptor immunoreactivity. Vis Neurosci. 2001 Sep-Oct; 18(5):695-702. PMID: 11925005.
      Citations: 4     Fields:    Translation:AnimalsCells
    31. Wiechmann AF, Smith AR. Melatonin receptor RNA is expressed in photoreceptors and displays a diurnal rhythm in Xenopus retina. Brain Res Mol Brain Res. 2001 Jul 13; 91(1-2):104-11. PMID: 11457497.
      Citations: 4     Fields:    Translation:AnimalsCells
    32. Roberts JE, Wiechmann AF, Hu DN. Melatonin receptors in human uveal melanocytes and melanoma cells. J Pineal Res. 2000 Apr; 28(3):165-71. PMID: 10739303.
      Citations: 5     Fields:    Translation:HumansCells
    33. Jacoby RA, Wiechmann AF, Amara SG, Leighton BH, Marshak DW. Diffuse bipolar cells provide input to OFF parasol ganglion cells in the macaque retina. J Comp Neurol. 2000 Jan 03; 416(1):6-18. PMID: 10578099.
      Citations: 28     Fields:    Translation:AnimalsCells
    34. Wiechmann AF, Burden MA. Regulation of AA-NAT and HIOMT gene expression by butyrate and cyclic AMP in Y79 human retinoblastoma cells. J Pineal Res. 1999 Sep; 27(2):116-21. PMID: 10496148.
      Citations: 5     Fields:    Translation:HumansCells
    35. Wiechmann AF, Campbell LD, Defoe DM. Melatonin receptor RNA expression in Xenopus retina. Brain Res Mol Brain Res. 1999 Jan 08; 63(2):297-303. PMID: 9878796.
      Citations: 3     Fields:    Translation:AnimalsCells
    36. Wiechmann AF, Sinacola MK. Diurnal expression of recoverin in the rat retina. Brain Res Mol Brain Res. 1997 May; 45(2):321-4. PMID: 9149107.
      Citations: 1     Fields:    Translation:AnimalsCells
    37. Yan XX, Wiechmann AF. Early expression of recoverin in a unique population of neurons in the human retina. Anat Embryol (Berl). 1997 Jan; 195(1):51-63. PMID: 9006715.
      Citations: 7     Fields:    Translation:HumansCells
    38. Wiechmann AF. Recoverin in cultured human retinoblastoma cells: enhanced expression during morphological differentiation. J Neurochem. 1996 Jul; 67(1):105-10. PMID: 8666979.
      Citations: 10     Fields:    Translation:HumansCells
    39. Wiechmann AF. Hydroxyindole-O-methyltransferase mRNA expression in a subpopulation of photoreceptors in the chicken retina. J Pineal Res. 1996 May; 20(4):217-25. PMID: 8836956.
      Citations: 1     Fields:    Translation:AnimalsCells
    40. Wiechmann AF, Haro KC, Bowden DW. Three microsatellite polymorphisms at the recoverin locus on chromosome 17. Hum Mol Genet. 1994 Jun; 3(6):1028. PMID: 7951220.
      Citations: 3     Fields:    Translation:HumansCells
    41. Craft CM, Whitmore DH, Wiechmann AF. Cone arrestin identified by targeting expression of a functional family. J Biol Chem. 1994 Feb 11; 269(6):4613-9. PMID: 8308033.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    42. Wiechmann AF, Akots G, Hammarback JA, Pettenati MJ, Rao PN, Bowden DW. Genetic and physical mapping of human recoverin: a gene expressed in retinal photoreceptors. Invest Ophthalmol Vis Sci. 1994 Feb; 35(2):325-31. PMID: 7906682.
      Citations: 4     Fields:    Translation:HumansCells
    43. Wiechmann AF, Wirsig-Wiechmann CR. Melatonin receptor distribution in the brain and retina of a lizard, Anolis carolinensis. Brain Behav Evol. 1994; 43(1):26-33. PMID: 8306189.
      Citations: 2     Fields:    Translation:Animals
    44. Wiechmann AF, Hammarback JA. Expression of recoverin mRNA in the human retina: localization by in situ hybridization. Exp Eye Res. 1993 Dec; 57(6):763-9. PMID: 8150028.
      Citations: 5     Fields:    Translation:HumansCells
    45. Wiechmann AF. Localization of hydroxyindole-O-methyltransferase in the retina: a re-evaluation. Exp Eye Res. 1993 Sep; 57(3):379-80. PMID: 8224025.
      Citations: 2     Fields:    Translation:Humans
    46. Wiechmann AF, Hammarback JA. Molecular cloning and nucleotide sequence of a cDNA encoding recoverin from human retina. Exp Eye Res. 1993 Apr; 56(4):463-70. PMID: 8500558.
      Citations: 2     Fields:    Translation:HumansCells
    47. Wiechmann AF, Craft CM. Localization of mRNA encoding the indolamine synthesizing enzyme, hydroxyindole-O-methyltransferase, in chicken pineal gland and retina by in situ hybridization. Neurosci Lett. 1993 Feb 19; 150(2):207-11. PMID: 8469423.
      Citations: 4     Fields:    Translation:AnimalsCells
    48. Wiechmann AF, Wirsig-Wiechmann CR. Distribution of melatonin receptors in the brain of the frog Rana pipiens as revealed by in vitro autoradiography. Neuroscience. 1993 Jan; 52(2):469-80. PMID: 8383821.
      Citations: 5     Fields:    Translation:AnimalsCells
    49. Wiechmann AF, Wirsig-Wiechmann CR. Asymmetric distribution of melatonin receptors in the brain of the lizard Anolis carolinensis. Brain Res. 1992 Oct 16; 593(2):281-6. PMID: 1333346.
      Citations: 3     Fields:    Translation:Animals
    50. Wiechmann AF, O'Steen WK. Melatonin increases photoreceptor susceptibility to light-induced damage. Invest Ophthalmol Vis Sci. 1992 May; 33(6):1894-902. PMID: 1582795.
      Citations: 24     Fields:    Translation:AnimalsCellsPHPublic Health
    51. Wiechmann AF, Font RL, Hollyfield JG. Idiopathic retinal degeneration in the dog: differential patterns of [3H]uridine incorporation and HIOMT-like immunoreactivity in surviving photoreceptors. Exp Eye Res. 1991 Mar; 52(3):311-20. PMID: 2015860.
      Citations:    Fields:    Translation:AnimalsCells
    52. Wiechmann AF, Wirsig-Wiechmann CR. Localization and quantification of high-affinity melatonin binding sites in Rana pipiens retina. J Pineal Res. 1991; 10(4):174-9. PMID: 1656012.
      Citations: 1     Fields:    Translation:AnimalsCells
    53. Wiechmann AF, Kyritsis AP, Fletcher RT, Chader GJ. Cyclic AMP and butyrate modulate melatonin synthesis in Y79 human retinoblastoma cells. J Neurochem. 1990 Jul; 55(1):208-14. PMID: 2162375.
      Citations:    Fields:    Translation:HumansCells
    54. Wiechmann AF, O'Steen WK. Hydroxyindole-O-methyltransferase in rat retinal bipolar cells: persistence following photoreceptor destruction. Brain Res. 1990 Jan 01; 506(1):14-8. PMID: 2302551.
      Citations:    Fields:    Translation:AnimalsCells
    55. Wiechmann AF, Hollyfield JG. HIOMT-like immunoreactivity in the vertebrate retina: a species comparison. Exp Eye Res. 1989 Dec; 49(6):1079-95. PMID: 2612586.
      Citations: 4     Fields:    Translation:Animals
    56. Wiechmann AF, Yang XL, Wu SM, Hollyfield JG. Melatonin enhances horizontal cell sensitivity in salamander retina. Brain Res. 1988 Jun 21; 453(1-2):377-80. PMID: 3401776.
      Citations: 11     Fields:    Translation:AnimalsCells
    57. Kyritsis AP, Wiechmann AF, Bok D, Chader GJ. Hydroxyindole-O-methyltransferase in Y-79 human retinoblastoma cells: effect of cell attachment. J Neurochem. 1987 May; 48(5):1612-6. PMID: 2435851.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    58. Wiechmann AF, Hollyfield JG. Localization of hydroxyindole-O-methyltransferase-like immunoreactivity in photoreceptors and cone bipolar cells in the human retina: a light and electron microscope study. J Comp Neurol. 1987 Apr 08; 258(2):253-66. PMID: 3294924.
      Citations:    Fields:    Translation:HumansCells
    59. Wiechmann AF, Hollyfield JG. Immunocytochemistry of retinitis pigmentosa retinas: localization of HIOMT immunoreactivity in surviving photoreceptor cells. Prog Clin Biol Res. 1987; 247:69-77. PMID: 3685046.
      Citations:    Fields:    Translation:HumansCells
    60. Wiechmann AF. Melatonin: parallels in pineal gland and retina. Exp Eye Res. 1986 Jun; 42(6):507-27. PMID: 3013666.
      Citations: 22     Fields:    Translation:Animals
    61. Wiechmann AF, Bok D, Horwitz J. Melatonin-binding in the frog retina: autoradiographic and biochemical analysis. Invest Ophthalmol Vis Sci. 1986 Feb; 27(2):153-63. PMID: 3484734.
      Citations: 5     Fields:    Translation:AnimalsCells
    62. Wiechmann AF, Bok D, Horwitz J. Localization of hydroxyindole-O-methyltransferase in the mammalian pineal gland and retina. Invest Ophthalmol Vis Sci. 1985 Mar; 26(3):253-65. PMID: 3882608.
      Citations: 7     Fields:    Translation:Animals
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