Robert Cichewicz to Humans
This is a "connection" page, showing publications Robert Cichewicz has written about Humans.
Connection Strength
1.145
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Persephacin Is a Broad-Spectrum Antifungal Aureobasidin Metabolite That Overcomes Intrinsic Resistance in Aspergillus fumigatus. J Nat Prod. 2023 08 25; 86(8):1980-1993.
Score: 0.049
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Resolving a Natural Product Cold Case: Elucidation of Fusapyrone Structure and Absolute Configuration and Demonstration of Their Fungal Biofilm Disrupting Properties. J Org Chem. 2023 Jul 07; 88(13):9167-9186.
Score: 0.048
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Appraisal of Fungus-Derived Xanthoquinodins as Broad-Spectrum Anti-Infectives Targeting Phylogenetically Diverse Human Pathogens. J Nat Prod. 2023 Jun 23; 86(6):1596-1605.
Score: 0.048
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In Vitro Susceptibility and Resistance of Mycoplasma genitalium to Nitroimidazoles. Antimicrob Agents Chemother. 2023 04 18; 67(4):e0000623.
Score: 0.047
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Leveraging Peptaibol Biosynthetic Promiscuity for Next-Generation Antiplasmodial Therapeutics. J Nat Prod. 2021 02 26; 84(2):503-517.
Score: 0.041
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Triple-Negative Breast Cancer Cells Exhibit Differential Sensitivity to Cardenolides from Calotropis gigantea. J Nat Prod. 2020 07 24; 83(7):2269-2280.
Score: 0.039
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Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. Demonstrate Selective Antiproliferative Effects in Cells Representing the Luminal Androgen Receptor Subtype of Triple Negative Breast Cancer. J Nat Prod. 2020 06 26; 83(6):2010-2024.
Score: 0.039
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Using the Cancer Dependency Map to Identify the Mechanism of Action of a Cytotoxic Alkenyl Derivative from the Fruit of Choerospondias axillaris. J Nat Prod. 2020 03 27; 83(3):584-592.
Score: 0.038
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Design and Application of a High-Throughput, High-Content Screening System for Natural Product Inhibitors of the Human Parasite Trichomonas vaginalis. ACS Infect Dis. 2019 08 09; 5(8):1456-1470.
Score: 0.037
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Natural-Product-Inspired Compounds as Countermeasures against the Liver Carcinogen Aflatoxin B1. J Nat Prod. 2019 06 28; 82(6):1694-1703.
Score: 0.036
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In Situ Ring Contraction and Transformation of the Rhizoxin Macrocycle through an Abiotic Pathway. J Nat Prod. 2019 04 26; 82(4):886-894.
Score: 0.036
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Anacolosins A-F and Corymbulosins X and Y, Clerodane Diterpenes from Anacolosa clarkii Exhibiting Cytotoxicity toward Pediatric Cancer Cell Lines. J Nat Prod. 2019 04 26; 82(4):928-936.
Score: 0.036
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Special Issue in Honor of Professor Phil Crews. J Nat Prod. 2017 03 24; 80(3):579-581.
Score: 0.031
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Opportunistic Sampling of Roadkill as an Entry Point to Accessing Natural Products Assembled by Bacteria Associated with Non-anthropoidal Mammalian Microbiomes. J Nat Prod. 2017 03 24; 80(3):598-608.
Score: 0.031
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Identification of Compounds with Efficacy against Malaria Parasites from Common North American Plants. J Nat Prod. 2016 Mar 25; 79(3):490-8.
Score: 0.029
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Polyketide glycosides from Bionectria ochroleuca inhibit Candida albicans biofilm formation. J Nat Prod. 2014 Oct 24; 77(10):2273-9.
Score: 0.026
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Bioactive sulfur-containing sulochrin dimers and other metabolites from an Alternaria sp. isolate from a Hawaiian soil sample. J Nat Prod. 2014 Oct 24; 77(10):2280-7.
Score: 0.026
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A potent HDAC inhibitor, 1-alaninechlamydocin, from a Tolypocladium sp. induces G2/M cell cycle arrest and apoptosis in MIA PaCa-2 cells. J Nat Prod. 2014 Jul 25; 77(7):1753-7.
Score: 0.026
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Cytotoxic dimeric epipolythiodiketopiperazines from the ascomycetous fungus Preussia typharum. J Nat Prod. 2014 Jun 27; 77(6):1459-66.
Score: 0.026
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Crowdsourcing natural products discovery to access uncharted dimensions of fungal metabolite diversity. Angew Chem Int Ed Engl. 2014 Jan 13; 53(3):804-9.
Score: 0.025
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Production of cytotoxic glidobactins/luminmycins by Photorhabdus asymbiotica in liquid media and live crickets. J Nat Prod. 2012 Nov 26; 75(11):2007-11.
Score: 0.023
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Waikialoid A suppresses hyphal morphogenesis and inhibits biofilm development in pathogenic Candida albicans. J Nat Prod. 2012 Apr 27; 75(4):707-15.
Score: 0.022
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Fungal biofilm inhibitors from a human oral microbiome-derived bacterium. Org Biomol Chem. 2012 Mar 14; 10(10):2044-50.
Score: 0.022
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Briarane diterpenes diminish COX-2 expression in human colon adenocarcinoma cells. J Nat Prod. 2011 Apr 25; 74(4):857-61.
Score: 0.021
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Bringing natural products into the fold - exploring the therapeutic lead potential of secondary metabolites for the treatment of protein-misfolding-related neurodegenerative diseases. Nat Prod Rep. 2011 Jan; 28(1):26-47.
Score: 0.020
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Reassessing the ichthyotoxin profile of cultured Prymnesium parvum (golden algae) and comparing it to samples collected from recent freshwater bloom and fish kill events in North America. Toxicon. 2010 Jun 15; 55(7):1396-404.
Score: 0.019
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Probing the metabolic aberrations underlying mutant huntingtin toxicity in yeast and assessing their degree of preservation in humans and mice. J Proteome Res. 2010 Jan; 9(1):404-12.
Score: 0.019
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Bioactivity profiling with parallel mass spectrometry reveals an assemblage of green tea metabolites affording protection against human huntingtin and alpha-synuclein toxicity. J Agric Food Chem. 2007 Nov 14; 55(23):9450-6.
Score: 0.016
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Stereochemical determination and bioactivity assessment of (S)-(+)-curcuphenol dimers isolated from the marine sponge Didiscus aceratus and synthesized through laccase biocatalysis. Bioorg Med Chem. 2005 Oct 01; 13(19):5600-12.
Score: 0.014
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Fungal-derived methyldeoxaphomins target Plasmodium falciparum segregation through the inhibition of PfActin1. Proc Natl Acad Sci U S A. 2025 Feb 25; 122(8):e2418871122.
Score: 0.014
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Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: archetypes for a unique class of selective and recyclable inhibitors. J Am Chem Soc. 2004 Nov 17; 126(45):14910-20.
Score: 0.013
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Chemoreactive 2,5-Diketopiperazines from a Penicillium sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways. J Nat Prod. 2024 Jul 26; 87(7):1826-1837.
Score: 0.013
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Psymberin, a potent sponge-derived cytotoxin from Psammocinia distantly related to the pederin family. Org Lett. 2004 Jun 10; 6(12):1951-4.
Score: 0.013
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Understanding the Antiplasmodial Action of Resistance-Refractory Xanthoquinodin A1. ACS Infect Dis. 2024 Jun 14; 10(6):2276-2287.
Score: 0.013
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Identification of fungal natural products with potent inhibition in Toxoplasma gondii. Microbiol Spectr. 2024 Apr 02; 12(4):e0414223.
Score: 0.013
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Inhibition of human tumor cell proliferation by novel anthraquinones from daylilies. Life Sci. 2004 Feb 20; 74(14):1791-9.
Score: 0.013
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microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data. Nat Microbiol. 2024 Feb; 9(2):336-345.
Score: 0.013
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Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cancer and HIV infection. Med Res Rev. 2004 Jan; 24(1):90-114.
Score: 0.013
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Identification of natural product modulators of Merkel cell carcinoma cell growth and survival. Sci Rep. 2021 06 30; 11(1):13597.
Score: 0.011
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Roseabol A, a New Peptaibol from the Fungus Clonostachys rosea. Molecules. 2021 Jun 11; 26(12).
Score: 0.011
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CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells. J Nat Prod. 2020 10 23; 83(10):3080-3092.
Score: 0.010
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Dimerization of resveratrol by the grapevine pathogen Botrytis cinerea. J Nat Prod. 2000 Jan; 63(1):29-33.
Score: 0.010
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Identification of C-6 as a New Site for Linker Conjugation to the Taccalonolide Microtubule Stabilizers. J Nat Prod. 2019 03 22; 82(3):583-588.
Score: 0.009
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Taccalonolide Microtubule Stabilizers Generated Using Semisynthesis Define the Effects of Mono Acyloxy Moieties at C-7 or C-15 and Disubstitutions at C-7 and C-25. J Nat Prod. 2018 03 23; 81(3):579-593.
Score: 0.008
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Structure-Activity Relationships of New Natural Product-Based Diaryloxazoles with Selective Activity against Androgen Receptor-Positive Breast Cancer Cells. J Med Chem. 2017 11 22; 60(22):9275-9289.
Score: 0.008
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Growth Inhibition of Colon Cancer and Melanoma Cells by Versiol Derivatives from a Paraconiothyrium Species. J Nat Prod. 2017 07 28; 80(7):2037-2044.
Score: 0.008
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Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ. J Nat Prod. 2017 02 24; 80(2):409-414.
Score: 0.008
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Maximiscin Induces DNA Damage, Activates DNA Damage Response Pathways, and Has Selective Cytotoxic Activity against a Subtype of Triple-Negative Breast Cancer. J Nat Prod. 2016 07 22; 79(7):1822-7.
Score: 0.007
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Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancer. Breast Cancer Res Treat. 2016 06; 157(3):475-88.
Score: 0.007
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Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke. Sci Rep. 2016 05 12; 6:25626.
Score: 0.007
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Texas Native Plants Yield Compounds with Cytotoxic Activities against Prostate Cancer Cells. J Nat Prod. 2016 Mar 25; 79(3):531-40.
Score: 0.007
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Targeting mosquito FREP1 with a fungal metabolite blocks malaria transmission. Sci Rep. 2015 Oct 06; 5:14694.
Score: 0.007
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Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nat Med. 2011 Dec 18; 18(1):153-8.
Score: 0.005
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Interrogating the bioactive pharmacophore of the latrunculin chemotype by investigating the metabolites of two taxonomically unrelated sponges. J Med Chem. 2008 Nov 27; 51(22):7234-42.
Score: 0.004
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Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties. J Med Chem. 2007 Aug 09; 50(16):3795-803.
Score: 0.004
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Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. J Med Chem. 2004 Jul 29; 47(16):4060-5.
Score: 0.003