Bone Morphogenetic Protein 4

"Bone Morphogenetic Protein 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A bone morphogenetic protein that is a potent inducer of bone formation. It also functions as a regulator of MESODERM formation during EMBRYONIC DEVELOPMENT.

Descriptor ID	D055415
MeSH Number(s)	D12.644.276.954.200.400 D12.776.467.942.200.400 D23.529.942.200.400
Concept/Terms	Bone Morphogenetic Protein 4 Bone Morphogenetic Protein 4 Bone Morphogenetic Protein 2B

Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Protein 4".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
TGF-beta Superfamily Proteins [D12.644.276.954]
Bone Morphogenetic Proteins [D12.644.276.954.200]
Bone Morphogenetic Protein 4 [D12.644.276.954.200.400]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
TGF-beta Superfamily Proteins [D12.776.467.942]
Bone Morphogenetic Proteins [D12.776.467.942.200]
Bone Morphogenetic Protein 4 [D12.776.467.942.200.400]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
TGF-beta Superfamily Proteins [D23.529.942]
Bone Morphogenetic Proteins [D23.529.942.200]
Bone Morphogenetic Protein 4 [D23.529.942.200.400]

Below are MeSH descriptors whose meaning is related to "Bone Morphogenetic Protein 4".

Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Protein 4".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bone Morphogenetic Protein 4" by people in this website by year, and whether "Bone Morphogenetic Protein 4" was a major or minor topic of these publications.

Bar chart showing 10 publications over 5 distinct years, with a maximum of 3 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	0	2	2
2007	0	2	2
2008	0	3	3
2009	1	1	2
2015	1	0	1

Below are the most recent publications written about "Bone Morphogenetic Protein 4" by people in Profiles.

Spicer LJ, Schutz LF, Aad PY. Effects of bone morphogenetic protein 4, gremlin, and connective tissue growth factor on estradiol and progesterone production by bovine granulosa cells. J Anim Sci. 2021 Nov 01; 99(11).

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Tan PS, Nakagawa S, Goossens N, Venkatesh A, Huang T, Ward SC, Sun X, Song WM, Koh A, Canasto-Chibuque C, Deshmukh M, Nair V, Mahajan M, Zhang B, Fiel MI, Kobayashi M, Kumada H, Hoshida Y. Clinicopathological indices to predict hepatocellular carcinoma molecular classification. Liver Int. 2016 Jan; 36(1):108-18.

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Csiszar A, Lehoux S, Ungvari Z. Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression. Antioxid Redox Signal. 2009 Jul; 11(7):1683-97.

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Bieniasz M, Oszajca K, Eusebio M, Kordiak J, Bartkowiak J, Szemraj J. The positive correlation between gene expression of the two angiogenic factors: VEGF and BMP-2 in lung cancer patients. Lung Cancer. 2009 Dec; 66(3):319-26.

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Csiszar A, Labinskyy N, Jo H, Ballabh P, Ungvari Z. Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H569-77.

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Lee D, Park C, Lee H, Lugus JJ, Kim SH, Arentson E, Chung YS, Gomez G, Kyba M, Lin S, Janknecht R, Lim DS, Choi K. ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell. 2008 May 08; 2(5):497-507.

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Khan SA, Nelson MS, Pan C, Gaffney PM, Gupta P. Endogenous heparan sulfate and heparin modulate bone morphogenetic protein-4 signaling and activity. Am J Physiol Cell Physiol. 2008 Jun; 294(6):C1387-97.

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Ungvari ZI. Endothelium-derived bone morphogenic protein antagonists may counteract the proatherogenic vascular effects of bone morphogenic protein 4. Circulation. 2007 Sep 11; 116(11):1221-3.

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Csiszar A, Labinskyy N, Smith KE, Rivera A, Bakker EN, Jo H, Gardner J, Orosz Z, Ungvari Z. Downregulation of bone morphogenetic protein 4 expression in coronary arterial endothelial cells: role of shear stress and the cAMP/protein kinase A pathway. Arterioscler Thromb Vasc Biol. 2007 Apr; 27(4):776-82.

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Spicer LJ, Aad PY, Allen D, Mazerbourg S, Hsueh AJ. Growth differentiation factor-9 has divergent effects on proliferation and steroidogenesis of bovine granulosa cells. J Endocrinol. 2006 May; 189(2):329-39.

View in: PubMed

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