"Macrophage-1 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
Descriptor ID |
D016177
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MeSH Number(s) |
D12.776.543.750.705.408.495.500 D12.776.543.750.705.408.600.500 D12.776.543.750.705.833.500
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Concept/Terms |
Macrophage-1 Antigen- Macrophage-1 Antigen
- Antigen, Macrophage-1
- Macrophage 1 Antigen
- CR3 Receptor
- Receptor, CR3
- Mo1 Antigen Receptor
- Antigen Receptor, Mo1
- Receptor, Mo1 Antigen
- Mo1 Glycoprotein Receptor
- Glycoprotein Receptor, Mo1
- Receptor, Mo1 Glycoprotein
- Integrin alpha(M)beta(2)
- Integrin alpha-M beta-2
- Integrin alpha M beta 2
- alpha-M beta-2, Integrin
- Complement 3 Receptor
- Receptor, Complement 3
- Mac-1 Antigen
- Mac 1 Antigen
- Adhesive Receptor Mac-1
- Mac-1 Adhesive Receptor
- Adhesive Receptor, Mac-1
- Mac 1 Adhesive Receptor
- Receptor, Mac-1 Adhesive
- Mac-1 Receptor
- Mac 1 Receptor
- Integrin alphaMbeta2
- alphaMbeta2, Integrin
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Below are MeSH descriptors whose meaning is more general than "Macrophage-1 Antigen".
Below are MeSH descriptors whose meaning is more specific than "Macrophage-1 Antigen".
This graph shows the total number of publications written about "Macrophage-1 Antigen" by people in this website by year, and whether "Macrophage-1 Antigen" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1992 | 1 | 0 | 1 |
1993 | 1 | 0 | 1 |
1999 | 0 | 1 | 1 |
2001 | 1 | 1 | 2 |
2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macrophage-1 Antigen" by people in Profiles.
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Sunderkötter C, Nikolic T, Dillon MJ, Van Rooijen N, Stehling M, Drevets DA, Leenen PJ. Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol. 2004 Apr 01; 172(7):4410-7.
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Gonzalez RJ, Moore EE, Ciesla DJ, Biffl WL, Johnson JL, Silliman CC. Mesenteric lymph is responsible for post-hemorrhagic shock systemic neutrophil priming. J Trauma. 2001 Dec; 51(6):1069-72.
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Ciesla DJ, Moore EE, Biffl WL, Gonzalez RJ, Silliman CC. Hypertonic saline attenuation of the neutrophil cytotoxic response is reversed upon restoration of normotonicity and reestablished by repeated hypertonic challenge. Surgery. 2001 May; 129(5):567-75.
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Zallen G, Moore EE, Johnson JL, Tamura DY, Ciesla DJ, Silliman CC. Posthemorrhagic shock mesenteric lymph primes circulating neutrophils and provokes lung injury. J Surg Res. 1999 May 15; 83(2):83-8.
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Drevets DA, Leenen PJ, Campbell PA. Complement receptor type 3 (CD11b/CD18) involvement is essential for killing of Listeria monocytogenes by mouse macrophages. J Immunol. 1993 Nov 15; 151(10):5431-9.
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Drevets DA, Canono BP, Campbell PA. Listericidal and nonlistericidal mouse macrophages differ in complement receptor type 3-mediated phagocytosis of L. monocytogenes and in preventing escape of the bacteria into the cytoplasm. J Leukoc Biol. 1992 Jul; 52(1):70-9.
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Drevets DA, Campbell PA. Roles of complement and complement receptor type 3 in phagocytosis of Listeria monocytogenes by inflammatory mouse peritoneal macrophages. Infect Immun. 1991 Aug; 59(8):2645-52.
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Roubey RA, Ross GD, Merrill JT, Walton F, Reed W, Winchester RJ, Buyon JP. Staurosporine inhibits neutrophil phagocytosis but not iC3b binding mediated by CR3 (CD11b/CD18). J Immunol. 1991 May 15; 146(10):3557-62.
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Merrill JT, Slade SG, Weissmann G, Winchester R, Buyon JP. Two pathways of CD11b/CD18-mediated neutrophil aggregation with different involvement of protein kinase C-dependent phosphorylation. J Immunol. 1990 Oct 15; 145(8):2608-15.