"Integrin alpha3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin alpha subunit that occurs as alternatively spliced isoforms. The isoforms are differentially expressed in specific cell types and at specific developmental stages. Integrin alpha3 combines with INTEGRIN BETA1 to form INTEGRIN ALPHA3BETA1 which is a heterodimer found primarily in epithelial cells.
| Descriptor ID |
D039422
|
| MeSH Number(s) |
D12.776.543.750.705.408.100.400
|
| Concept/Terms |
Integrin alpha3- Integrin alpha3
- alpha3, Integrin
- alpha(3) Integrin
- CD49c Antigens
- Fusion Regulatory Protein-2
- Fusion Regulatory Protein 2
- Antigens, CD49c
- CD49c Antigen
- Antigen, CD49c
- FRP-2
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha3".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha3".
This graph shows the total number of publications written about "Integrin alpha3" by people in this website by year, and whether "Integrin alpha3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Integrin alpha3" by people in Profiles.
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Zinc-Dependent Regulation of ZEB1 and YAP1 Coactivation Promotes Epithelial-Mesenchymal Transition Plasticity and Metastasis in Pancreatic Cancer. Gastroenterology. 2021 04; 160(5):1771-1783.e1.
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ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin a3ß1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells. Gastroenterology. 2020 02; 158(3):679-692.e1.
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Race-specific molecular alterations correlate with differential outcomes for black and white endometrioid endometrial cancer patients. Cancer. 2017 Oct 15; 123(20):4004-4012.
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Localization of alpha integrin subunits in the neural retina of the tiger salamander. Graefes Arch Clin Exp Ophthalmol. 2001 Apr; 239(4):278-87.