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NLR Family, Pyrin Domain-Containing 3 Protein

"NLR Family, Pyrin Domain-Containing 3 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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An NLR protein that contains an N-terminal PYRIN DOMAIN and ATP-binding site and 9 C-terminal LEUCINE-rich repeats; it is expressed primarily by MACROPHAGES. It is a core component of the INFLAMMASOME and directs its assembly in response to pathogen infection and damage-associated stimuli. Mutations in the NLRP3 gene are associated with FAMILIAL COLD AUTOINFLAMMATORY SYNDROME.


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This graph shows the total number of publications written about "NLR Family, Pyrin Domain-Containing 3 Protein" by people in this website by year, and whether "NLR Family, Pyrin Domain-Containing 3 Protein" was a major or minor topic of these publications.
Bar chart showing 6 publications over 4 distinct years, with a maximum of 2 publications in 2015 and 2016
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