Receptor, Interferon alpha-beta
"Receptor, Interferon alpha-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.
| Descriptor ID |
D053633
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| MeSH Number(s) |
D12.776.543.750.705.852.400.500
|
| Concept/Terms |
Receptor, Interferon alpha-beta- Receptor, Interferon alpha-beta
- Receptor, Interferon alpha beta
- IFN-alphaR
- Interferon alpha Receptor
- alpha Receptor, Interferon
- Type I Interferon Receptor
- Interferon alpha-beta Receptor
- Interferon alpha beta Receptor
- Interferon alphabeta Receptors
- Receptors, Interferon alphabeta
- Receptor, Interferon alpha
- IFN-alphabetaR
- IFN alphabetaR
- Interferon alpha Receptors
- Receptors, Interferon alpha
- alpha Receptors, Interferon
Interferon alpha-beta Receptor Chain 2- Interferon alpha-beta Receptor Chain 2
- Interferon alpha beta Receptor Chain 2
- Interferon alpha-beta Receptor IFNAR2 Subunit
- Interferon alpha beta Receptor IFNAR2 Subunit
- Interferon alpha-beta Receptor-2
- Interferon alpha beta Receptor 2
- Receptor-2, Interferon alpha-beta
- alpha-beta Receptor-2, Interferon
- IFNAR2 Subunit, Interferon alpha-beta Receptor
- IFNAR2 Subunit, Interferon alpha beta Receptor
Interferon alpha-beta Receptor Chain 1- Interferon alpha-beta Receptor Chain 1
- Interferon alpha beta Receptor Chain 1
- Interferon alpha-beta Receptor IFNAR1 Subunit
- Interferon alpha beta Receptor IFNAR1 Subunit
- Interferon alpha-beta Receptor-1
- Interferon alpha beta Receptor 1
- Receptor-1, Interferon alpha-beta
- alpha-beta Receptor-1, Interferon
- IFNAR1 Subunit, Interferon alpha-beta Receptor
- IFNAR1 Subunit, Interferon alpha beta Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptor, Interferon alpha-beta".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Interferon alpha-beta".
This graph shows the total number of publications written about "Receptor, Interferon alpha-beta" by people in this website by year, and whether "Receptor, Interferon alpha-beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, Interferon alpha-beta" by people in Profiles.
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Noncognate Signals Drive Enhanced Effector CD8+ T Cell Responses through an IFNAR1-Dependent Pathway after Infection with the Prototypic Vaccine, 0?NLS, against Herpes Simplex Virus 1. J Virol. 2022 03 23; 96(6):e0172421.
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Anifrolumab, an Anti-Interferon-a Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus. Arthritis Rheumatol. 2017 02; 69(2):376-386.
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Type I interferon receptor deficiency prevents murine Sjogren's syndrome. J Dent Res. 2013 May; 92(5):444-9.
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Salivary gland hypofunction induced by activation of innate immunity is dependent on type I interferon signaling. J Oral Pathol Med. 2013 Jan; 42(1):66-72.
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Deficiency of type I IFN receptor in lupus-prone New Zealand mixed 2328 mice decreases dendritic cell numbers and activation and protects from disease. J Immunol. 2009 Nov 01; 183(9):6021-9.
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Type 1 interferons cool the inflamed brain. Immunity. 2008 May; 28(5):600-2.