"Tandem Mass Spectrometry" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.
| Descriptor ID |
D053719
|
| MeSH Number(s) |
E05.196.566.880
|
| Concept/Terms |
Tandem Mass Spectrometry- Tandem Mass Spectrometry
- Mass Spectrometry, Tandem
- Mass Spectrometry-Mass Spectrometry
- Mass Spectrometry Mass Spectrometry
|
Below are MeSH descriptors whose meaning is more general than "Tandem Mass Spectrometry".
Below are MeSH descriptors whose meaning is more specific than "Tandem Mass Spectrometry".
This graph shows the total number of publications written about "Tandem Mass Spectrometry" by people in this website by year, and whether "Tandem Mass Spectrometry" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 6 | 7 |
| 2010 | 3 | 4 | 7 |
| 2011 | 1 | 3 | 4 |
| 2012 | 0 | 5 | 5 |
| 2013 | 2 | 4 | 6 |
| 2014 | 0 | 6 | 6 |
| 2015 | 0 | 4 | 4 |
| 2016 | 1 | 4 | 5 |
| 2017 | 3 | 1 | 4 |
| 2018 | 3 | 2 | 5 |
| 2019 | 5 | 4 | 9 |
| 2020 | 0 | 5 | 5 |
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Below are the most recent publications written about "Tandem Mass Spectrometry" by people in Profiles.
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Hanas JS, Hocker JRS, Evangeline B, Prabhakaran V, Oommen A, Rajshekhar V, Drevets DA, Carabin H. Distinguishing patients with idiopathic epilepsy from solitary cysticercus granuloma epilepsy and biochemical phenotype assessment using a serum biomolecule profiling platform. PLoS One. 2020; 15(8):e0237064.
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Hocker JR, Lerner M, Lightfoot SA, Peyton MD, Thompson JL, Deb S, Reinersman M, Hanas RJ, Postier RG, Edil BH, Burkhart HM, Hanas JS. Serum discrimination and phenotype assessment of coronary artery disease patents with and without type 2 diabetes prior to coronary artery bypass graft surgery. PLoS One. 2020; 15(8):e0234539.
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Zhu Y, Wang W, Yang Z. Combining Mass Spectrometry with Paternò-Büchi Reaction to Determine Double-Bond Positions in Lipids at the Single-Cell Level. Anal Chem. 2020 08 18; 92(16):11380-11387.
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Kasus-Jacobi A, Land CA, Stock AJ, Washburn JL, Pereira HA. Antimicrobial Peptides Derived from the Immune Defense Protein CAP37 Inhibit TLR4 Activation by S100A9. Invest Ophthalmol Vis Sci. 2020 04 09; 61(4):16.
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Cupp-Sutton KA, Wu S. High-throughput quantitative top-down proteomics. Mol Omics. 2020 04 01; 16(2):91-99.
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Fornelli L, Srzentic K, Toby TK, Doubleday PF, Huguet R, Mullen C, Melani RD, Dos Santos Seckler H, DeHart CJ, Weisbrod CR, Durbin KR, Greer JB, Early BP, Fellers RT, Zabrouskov V, Thomas PM, Compton PD, Kelleher NL. Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics. Mol Cell Proteomics. 2020 02; 19(2):405-420.
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Huguet R, Mullen C, Srzentic K, Greer JB, Fellers RT, Zabrouskov V, Syka JEP, Kelleher NL, Fornelli L. Proton Transfer Charge Reduction Enables High-Throughput Top-Down Analysis of Large Proteoforms. Anal Chem. 2019 12 17; 91(24):15732-15739.
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Yu D, Wang Z, Cupp-Sutton KA, Liu X, Wu S. Deep Intact Proteoform Characterization in Human Cell Lysate Using High-pH and Low-pH Reversed-Phase Liquid Chromatography. J Am Soc Mass Spectrom. 2019 Dec; 30(12):2502-2513.
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Melani RD, Srzentic K, Gerbasi VR, McGee JP, Huguet R, Fornelli L, Kelleher NL. Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry. MAbs. 2019 Nov-Dec; 11(8):1351-1357.
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Zimmerman CN, Sharer JD. Analytical Methods for Quantitative Plasma Carnitine Determination. Curr Protoc Hum Genet. 2019 06; 102(1):e85.