"Polypharmacy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The use of multiple drugs administered to the same patient, most commonly seen in elderly patients. It includes also the administration of excessive medication. Since in the United States most drugs are dispensed as single-agent formulations, polypharmacy, though using many drugs administered to the same patient, must be differentiated from DRUG COMBINATIONS, single preparations containing two or more drugs as a fixed dose, and from DRUG THERAPY, COMBINATION, two or more drugs administered separately for a combined effect. (From Segen, Dictionary of Modern Medicine, 1992)
| Descriptor ID |
D019338
|
| MeSH Number(s) |
E02.319.698
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polypharmacy".
Below are MeSH descriptors whose meaning is more specific than "Polypharmacy".
This graph shows the total number of publications written about "Polypharmacy" by people in this website by year, and whether "Polypharmacy" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Polypharmacy" by people in Profiles.
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Depression and polypharmacy are risk factors for activity limitation in type 2 diabetes. Chronic Illn. 2022 06; 18(2):320-329.
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Frequency and Predictors of Polypharmacy in US Medicare Patients: A Cross-Sectional Analysis at the Patient and Physician Levels. Drugs Aging. 2020 01; 37(1):57-65.
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Characterization of Chronic Multiclass Psychotropic Polypharmacy and Psychotherapy in Foster Care Youth in a State Medicaid Population. J Manag Care Spec Pharm. 2019 Dec; 25(12):1340-1348.
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The prevalence, predictors and outcomes of guideline-directed medical therapy in patients with acute myocardial infarction undergoing PCI, an analysis from the PROMETHEUS registry. Catheter Cardiovasc Interv. 2019 02 15; 93(3):E112-E119.
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Impact of age, comorbidity, and polypharmacy on the efficacy and safety of edoxaban for the treatment of venous thromboembolism: An analysis of the randomized, double-blind Hokusai-VTE trial. Thromb Res. 2018 02; 162:7-14.
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Prevalence, patterns and factors associated with psychotropic use in older adults with intellectual disabilities in Ireland. J Intellect Disabil Res. 2017 10; 61(10):969-983.
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Rational use of multiple medications in medicine and psychiatry: a dimensional perspective. J Psychiatr Pract. 2013 Jan; 19(1):54-61.
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Neuropsychiatric manifestations of phenytoin toxicity in an elderly patient. J Psychiatr Pract. 2007 Jan; 13(1):49-54.
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Suboptimal pharmacotherapy in a tribal nursing home. J Am Med Dir Assoc. 2007 Jan; 8(1):1-7.
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Medication management in the elderly. J Okla State Med Assoc. 2003 Mar; 96(3):116-22.