Platelet Endothelial Cell Adhesion Molecule-1
"Platelet Endothelial Cell Adhesion Molecule-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule, composed of a series of Ig-like domains, and expressed on virtually all MONOCYTES; PLATELETS; and GRANULOCYTES. PECAM-1 is highly expressed on endothelial cells and concentrated at the junctions between them. It is essential for TRANSENDOTHELIAL MIGRATION of leukocytes and removal of apoptotic cells by PHAGOCYTES.
| Descriptor ID |
D019408
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| MeSH Number(s) |
D12.776.395.550.200.131 D12.776.543.550.200.131 D23.050.301.264.900.131 D23.050.301.350.131 D23.101.100.900.131
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Platelet Endothelial Cell Adhesion Molecule-1".
Below are MeSH descriptors whose meaning is more specific than "Platelet Endothelial Cell Adhesion Molecule-1".
This graph shows the total number of publications written about "Platelet Endothelial Cell Adhesion Molecule-1" by people in this website by year, and whether "Platelet Endothelial Cell Adhesion Molecule-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Platelet Endothelial Cell Adhesion Molecule-1" by people in Profiles.
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Tumor Microvessel Density as a Potential Predictive Marker for Bevacizumab Benefit: GOG-0218 Biomarker Analyses. J Natl Cancer Inst. 2017 11 01; 109(11).
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Characterization of cells from patient-derived fibrovascular membranes in proliferative diabetic retinopathy. Mol Vis. 2015; 21:673-87.
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EVI1 targets platelet endothelial cell adhesion molecule and up-regulates its expression in chronic myeloid leukemia. Leuk Lymphoma. 2014 Apr; 55(4):954-6.
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Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cells in vivo. Int J Cancer. 2013 Mar 01; 132(5):1201-12.
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Dysregulation of the microvasculature in nonlesional non-sun-exposed skin of patients with lupus nephritis. J Rheumatol. 2012 Mar; 39(3):510-5.
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Effect of a novel DNA vaccine on angiogenesis and tumor growth in vivo. Arch Otolaryngol Head Neck Surg. 2010 Sep; 136(9):859-64.
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Temporal requirement of RPE-derived VEGF in the development of choroidal vasculature. J Neurochem. 2010 Mar; 112(6):1584-92.
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Activation of apoptosis by 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos. Cancer Res. 2008 Oct 15; 68(20):8573-81.
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PECAM-1 polymorphism affects monocyte adhesion to endothelial cells. Transplantation. 2008 Feb 15; 85(3):471-7.
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Lymphatic vessel density and function in experimental bladder cancer. BMC Cancer. 2007 Nov 29; 7:219.