Single-Chain Antibodies

"Single-Chain Antibodies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A form of antibodies consisting only of the variable regions of the heavy and light chains (FV FRAGMENTS), connected by a small linker peptide. They are less immunogenic than complete immunoglobulin and thus have potential therapeutic use.

Descriptor ID	D057127
MeSH Number(s)	D12.644.541.500.650.500.800 D12.776.124.486.485.114.224.785 D12.776.124.486.485.680.650.500.800 D12.776.124.790.651.680.650.500.800 D12.776.377.715.548.680.650.500.795
Concept/Terms	Single-Chain Antibodies Single-Chain Antibodies Antibodies, Single-Chain Single Chain Antibodies ScFv Antibodies Antibodies, ScFv Single-Chain Fv Fv, Single-Chain Single Chain Fv Single-Chain Fv Antibody Antibody, Single-Chain Fv Fv Antibody, Single-Chain Single Chain Fv Antibody Single-Chain Variable Fragment Fragment, Single-Chain Variable Single Chain Variable Fragment Variable Fragment, Single-Chain Single-Chain Variable Fragment Antibodies Single Chain Variable Fragment Antibodies Single-Chain Variable Fragment Antibody Single Chain Variable Fragment Antibody Single-Chain Variable Fragments Fragments, Single-Chain Variable Single Chain Variable Fragments Variable Fragments, Single-Chain Fv Antibody Fragments, Single-Chain Fv Antibody Fragments, Single Chain Single-Chain Fv Antibody Fragments Single Chain Fv Antibody Fragments

Below are MeSH descriptors whose meaning is more general than "Single-Chain Antibodies".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Peptide Fragments [D12.644.541]
Immunoglobulin Fragments [D12.644.541.500]
Immunoglobulin Fab Fragments [D12.644.541.500.650]
Immunoglobulin Variable Region [D12.644.541.500.650.500]
Single-Chain Antibodies [D12.644.541.500.650.500.800]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Immunoproteins [D12.776.124.486]
Immunoglobulins [D12.776.124.486.485]
Antibodies [D12.776.124.486.485.114]
Antibodies, Monoclonal [D12.776.124.486.485.114.224]
Single-Chain Antibodies [D12.776.124.486.485.114.224.785]
Immunoglobulin Fragments [D12.776.124.486.485.680]
Immunoglobulin Fab Fragments [D12.776.124.486.485.680.650]
Immunoglobulin Variable Region [D12.776.124.486.485.680.650.500]
Single-Chain Antibodies [D12.776.124.486.485.680.650.500.800]
Serum Globulins [D12.776.124.790]
Immunoglobulins [D12.776.124.790.651]
Immunoglobulin Fragments [D12.776.124.790.651.680]
Immunoglobulin Fab Fragments [D12.776.124.790.651.680.650]
Immunoglobulin Variable Region [D12.776.124.790.651.680.650.500]
Single-Chain Antibodies [D12.776.124.790.651.680.650.500.800]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Immunoglobulins [D12.776.377.715.548]
Immunoglobulin Fragments [D12.776.377.715.548.680]
Immunoglobulin Fab Fragments [D12.776.377.715.548.680.650]
Immunoglobulin Variable Region [D12.776.377.715.548.680.650.500]
Single-Chain Antibodies [D12.776.377.715.548.680.650.500.795]

Below are MeSH descriptors whose meaning is related to "Single-Chain Antibodies".

Below are MeSH descriptors whose meaning is more specific than "Single-Chain Antibodies".

publications

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