"Receptors, Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.
| Descriptor ID |
D054411
|
| MeSH Number(s) |
D12.776.543.750.650.500
|
| Concept/Terms |
Receptors, Leptin- Receptors, Leptin
- Leptin-Binding Protein
- Leptin Binding Protein
- Receptor, Leptin
- Leptin Receptor
- Antigens, CD295
- LEPR Protein
- OB Receptor
- Receptor, OB
- CD295 Antigens
- Leptin Receptors
OBRb Receptor- OBRb Receptor
- Receptor, OBRb
- Leptin Receptor, Large Isoform
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Leptin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Leptin".
This graph shows the total number of publications written about "Receptors, Leptin" by people in this website by year, and whether "Receptors, Leptin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
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Below are the most recent publications written about "Receptors, Leptin" by people in Profiles.
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Li C, Ramahi E, Nijland MJ, Choi J, Myers DA, Nathanielsz PW, McDonald TJ. Up-regulation of the fetal baboon hypothalamo-pituitary-adrenal axis in intrauterine growth restriction: coincidence with hypothalamic glucocorticoid receptor insensitivity and leptin receptor down-regulation. Endocrinology. 2013 Jul; 154(7):2365-73.
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Ducsay CA, Furuta K, Vargas VE, Kaushal KM, Singleton K, Hyatt K, Myers DA. Leptin receptor antagonist treatment ameliorates the effects of long-term maternal hypoxia on adrenal expression of key steroidogenic genes in the ovine fetus. Am J Physiol Regul Integr Comp Physiol. 2013 Mar 15; 304(6):R435-42.
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Harrod JS, Rada CC, Pierce SL, England SK, Lamping KG. Altered contribution of RhoA/Rho kinase signaling in contractile activity of myometrium in leptin receptor-deficient mice. Am J Physiol Endocrinol Metab. 2011 Aug; 301(2):E362-9.
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Wisniewski AB, Chernausek SD. Gender in childhood obesity: family environment, hormones, and genes. Gend Med. 2009; 6 Suppl 1:76-85.
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Ducsay CA, Hyatt K, Mlynarczyk M, Kaushal KM, Myers DA. Long-term hypoxia increases leptin receptors and plasma leptin concentrations in the late-gestation ovine fetus. Am J Physiol Regul Integr Comp Physiol. 2006 Nov; 291(5):R1406-13.
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Fenton JI, Hursting SD, Perkins SN, Hord NG. Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line. Carcinogenesis. 2006 Jul; 27(7):1507-15.
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Kloek C, Haq AK, Dunn SL, Lavery HJ, Banks AS, Myers MG. Regulation of Jak kinases by intracellular leptin receptor sequences. J Biol Chem. 2002 Nov 01; 277(44):41547-55.
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Spicer LJ. Leptin: a possible metabolic signal affecting reproduction. Domest Anim Endocrinol. 2001 Nov; 21(4):251-70.