Sialic Acid Binding Ig-like Lectin 1
"Sialic Acid Binding Ig-like Lectin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sialic acid binding lectin that was originally identified as an adhesion molecule for inflammatory MACROPHAGES and activated MONOCYTES. This protein is the largest known siglec subtype and contains 16 immunoglobulin C2-set domains. It plays a role in cell to cell interactions and interactions with bacteria.
| Descriptor ID |
D063267
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| MeSH Number(s) |
D12.776.503.921.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sialic Acid Binding Ig-like Lectin 1".
Below are MeSH descriptors whose meaning is more specific than "Sialic Acid Binding Ig-like Lectin 1".
This graph shows the total number of publications written about "Sialic Acid Binding Ig-like Lectin 1" by people in this website by year, and whether "Sialic Acid Binding Ig-like Lectin 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sialic Acid Binding Ig-like Lectin 1" by people in Profiles.
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Melanoma growth and lymph node metastasis is independent of host CD169 expression. Biochem Biophys Res Commun. 2017 05 13; 486(4):965-970.
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The CD169 sialoadhesin molecule mediates cytotoxic T-cell responses to tumour apoptotic vesicles. Immunol Cell Biol. 2016 05; 94(5):430-8.
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CD169 mediates the capture of exosomes in spleen and lymph node. Blood. 2014 Jan 09; 123(2):208-16.
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CD169? macrophages provide a niche promoting erythropoiesis under homeostasis and stress. Nat Med. 2013 Apr; 19(4):429-36.