Tacrolimus Binding Protein 1A
"Tacrolimus Binding Protein 1A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS.
| Descriptor ID |
D022061
|
| MeSH Number(s) |
D08.811.399.325.500.400.700.500 D12.776.543.750.705.400.700.500 D12.776.827.275.700.500
|
| Concept/Terms |
Tacrolimus Binding Protein 1A- Tacrolimus Binding Protein 1A
- Macrophilin-12
- Macrophilin 12
- FKBP-12
- FKBP 12
- FKBP12
- FK506-Binding Protein 1
- FK506 Binding Protein 1
- FK506-Binding Protein 1A
- FK506 Binding Protein 1A
|
Below are MeSH descriptors whose meaning is more general than "Tacrolimus Binding Protein 1A".
Below are MeSH descriptors whose meaning is more specific than "Tacrolimus Binding Protein 1A".
This graph shows the total number of publications written about "Tacrolimus Binding Protein 1A" by people in this website by year, and whether "Tacrolimus Binding Protein 1A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tacrolimus Binding Protein 1A" by people in Profiles.
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Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function. J Biol Chem. 2014 Sep 12; 289(37):25556-70.
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Ryanodine receptors: structure, expression, molecular details, and function in calcium release. Cold Spring Harb Perspect Biol. 2010 Nov; 2(11):a003996.
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Overexpression of the EGFR/FKBP12/HIF-2alpha pathway identified in childhood astrocytomas by angiogenesis gene profiling. Cancer Res. 2003 Apr 15; 63(8):1865-70.