Death Effector Domain

"Death Effector Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A homotypic protein interaction module of the death domain superfamily that is composed of a bundle of six alpha-helices. The death effector domain shares sequence and structural similarities with the DEATH DOMAIN and CASPASE RECRUITMENT DOMAIN. It occurs in many proteins with essential functions in APOPTOSIS.

Descriptor ID	D000071461
MeSH Number(s)	G02.111.570.820.709.275.750.500.395.750
Concept/Terms	Death Effector Domain Death Effector Domain Death Effector Domains DED Domain DED Domains

Below are MeSH descriptors whose meaning is more general than "Death Effector Domain".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Molecular Conformation [G02.111.570.820]
Protein Conformation [G02.111.570.820.709]
Protein Structural Elements [G02.111.570.820.709.275]
Protein Domains [G02.111.570.820.709.275.750]
Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]
Death Domain Superfamily [G02.111.570.820.709.275.750.500.395]
Death Effector Domain [G02.111.570.820.709.275.750.500.395.750]

Below are MeSH descriptors whose meaning is related to "Death Effector Domain".

Below are MeSH descriptors whose meaning is more specific than "Death Effector Domain".

publications

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