Receptors, Prostaglandin E, EP4 Subtype
"Receptors, Prostaglandin E, EP4 Subtype" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of prostaglandin E receptors that specifically couples to GS ALPHA GTP-BINDING PROTEIN SUBUNITS and subsequently activates ADENYLYL CYCLASES. The receptor may also signal through the activation of PHOSPHATIDYLINOSITOL 3-KINASE.
| Descriptor ID |
D058309
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| MeSH Number(s) |
D12.776.543.750.695.200.700.600.400
|
| Concept/Terms |
Receptors, Prostaglandin E, EP4 Subtype- Receptors, Prostaglandin E, EP4 Subtype
- Prostaglandin E Receptor 4
- Prostaglandin EP4 Receptors
- EP4 Receptors, Prostaglandin
- Receptors, Prostaglandin EP4
- Prostanoid Receptor EP4
- EP4, Prostanoid Receptor
- Receptor EP4, Prostanoid
- Receptor, Prostaglandin EP4
- EP4 Receptor, Prostaglandin
- Prostaglandin EP4 Receptor
- PGE Receptor, EP4 Subtype
- Prostaglandin E2 Receptor, EP4 Subtype
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Prostaglandin E, EP4 Subtype".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Prostaglandin E, EP4 Subtype".
This graph shows the total number of publications written about "Receptors, Prostaglandin E, EP4 Subtype" by people in this website by year, and whether "Receptors, Prostaglandin E, EP4 Subtype" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Prostaglandin E, EP4 Subtype" by people in Profiles.
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Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. Am J Hum Genet. 2021 03 04; 108(3):431-445.
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Prostaglandin E2, a postulated mediator of neurovascular coupling, at low concentrations dilates whereas at higher concentrations constricts human cerebral parenchymal arterioles. Prostaglandins Other Lipid Mediat. 2020 02; 146:106389.
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EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway. Prostaglandins Other Lipid Mediat. 2007 Feb; 83(1-2):112-20.
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Prosurvival and antiapoptotic effects of PGE2 in radiation injury are mediated by EP2 receptor in intestine. Am J Physiol Gastrointest Liver Physiol. 2003 Mar; 284(3):G490-8.