"Th17 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of helper-effector T-lymphocytes which synthesize and secrete INTERLEUKINS IL-17; IL-17F; and IL-22. These cytokines are involved in host defenses and tissue inflammation in autoimmune diseases.
| Descriptor ID |
D058504
|
| MeSH Number(s) |
A11.118.637.555.567.550.500.400.915 A11.118.637.555.567.569.200.400.915 A11.118.637.555.567.569.500.400.915 A15.145.229.637.555.567.550.500.400.770 A15.145.229.637.555.567.569.200.400.770 A15.145.229.637.555.567.569.500.400.770 A15.382.490.555.567.550.500.400.915 A15.382.490.555.567.569.200.400.915 A15.382.490.555.567.569.500.400.915
|
| Concept/Terms |
Th17 Cells- Th17 Cells
- Cell, Th17
- Cells, Th17
- Th17 Cell
- TH-17 Cells
- Cell, TH-17
- Cells, TH-17
- TH 17 Cells
- TH-17 Cell
- T Helper 17 Cells
- Type 17 Helper T Cells
|
Below are MeSH descriptors whose meaning is more general than "Th17 Cells".
- Anatomy [A]
- Cells [A11]
- Blood Cells [A11.118]
- Leukocytes [A11.118.637]
- Leukocytes, Mononuclear [A11.118.637.555]
- Lymphocytes [A11.118.637.555.567]
- Lymphocyte Subsets [A11.118.637.555.567.550]
- T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
- Th17 Cells [A11.118.637.555.567.550.500.400.915]
- T-Lymphocytes [A11.118.637.555.567.569]
- CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
- Th17 Cells [A11.118.637.555.567.569.200.400.915]
- T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
- Th17 Cells [A11.118.637.555.567.569.500.400.915]
- Hemic and Immune Systems [A15]
- Blood [A15.145]
- Blood Cells [A15.145.229]
- Leukocytes [A15.145.229.637]
- Leukocytes, Mononuclear [A15.145.229.637.555]
- Lymphocytes [A15.145.229.637.555.567]
- Lymphocyte Subsets [A15.145.229.637.555.567.550]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
- Th17 Cells [A15.145.229.637.555.567.550.500.400.770]
- T-Lymphocytes [A15.145.229.637.555.567.569]
- CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
- Th17 Cells [A15.145.229.637.555.567.569.200.400.770]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
- Th17 Cells [A15.145.229.637.555.567.569.500.400.770]
- Immune System [A15.382]
- Leukocytes [A15.382.490]
- Leukocytes, Mononuclear [A15.382.490.555]
- Lymphocytes [A15.382.490.555.567]
- Lymphocyte Subsets [A15.382.490.555.567.550]
- T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
- Th17 Cells [A15.382.490.555.567.550.500.400.915]
- T-Lymphocytes [A15.382.490.555.567.569]
- CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
- Th17 Cells [A15.382.490.555.567.569.200.400.915]
- T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
- Th17 Cells [A15.382.490.555.567.569.500.400.915]
Below are MeSH descriptors whose meaning is more specific than "Th17 Cells".
This graph shows the total number of publications written about "Th17 Cells" by people in this website by year, and whether "Th17 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 2 | 3 | 5 |
| 2012 | 3 | 3 | 6 |
| 2013 | 3 | 2 | 5 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 1 | 3 |
| 2020 | 3 | 0 | 3 |
| 2021 | 2 | 0 | 2 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Th17 Cells" by people in Profiles.
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Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis. J Clin Invest. 2025 Mar 17; 135(6).
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Interferon-ß Intensifies Interleukin-23-Driven Pathogenicity of T Helper Cells in Neuroinflammatory Disease. Cells. 2021 08 20; 10(8).
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Pertussis Toxin Inhibits Encephalitogenic T-Cell Infiltration and Promotes a B-Cell-Driven Disease during Th17-EAE. Int J Mol Sci. 2021 Mar 13; 22(6).
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T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis. Nat Commun. 2020 10 26; 11(1):5406.
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E3 Ubiquitin Ligase Von Hippel-Lindau Protein Promotes Th17 Differentiation. J Immunol. 2020 08 15; 205(4):1009-1023.
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Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica. Nat Commun. 2020 06 05; 11(1):2856.
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Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing. Sci Rep. 2020 03 05; 10(1):4123.
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PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-ß1 production. Sci Transl Med. 2018 09 26; 10(460).
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Ichthyosis molecular fingerprinting shows profound TH17 skewing and a unique barrier genomic signature. J Allergy Clin Immunol. 2019 02; 143(2):604-618.
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Role of TFH Cells in Promoting T Helper 17-Induced Neuroinflammation. Front Immunol. 2018; 9:382.