"Scleroderma, Diffuse" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rapid onset form of SYSTEMIC SCLERODERMA with progressive widespread SKIN thickening over the arms, the legs and the trunk, resulting in stiffness and disability.
| Descriptor ID |
D045743
|
| MeSH Number(s) |
C17.300.799.602 C17.800.784.602
|
| Concept/Terms |
Scleroderma, Diffuse- Scleroderma, Diffuse
- Scleroderma, Progressive
- Progressive Scleroderma
- Diffuse Cutaneous Systemic Sclerosis
- Sudden Onset Scleroderma
- Scleroderma, Sudden Onset
- Sclerodermas, Sudden Onset
- Sudden Onset Sclerodermas
- Diffuse Systemic Sclerosis
- Diffuse Systemic Scleroses
- Scleroses, Diffuse Systemic
- Sclerosis, Diffuse Systemic
- Systemic Scleroses, Diffuse
- Systemic Sclerosis, Diffuse
- Diffuse Scleroderma
- Sclerosis, Progressive Systemic
- Progressive Systemic Sclerosis
- Systemic Sclerosis, Progressive
|
Below are MeSH descriptors whose meaning is more general than "Scleroderma, Diffuse".
Below are MeSH descriptors whose meaning is more specific than "Scleroderma, Diffuse".
This graph shows the total number of publications written about "Scleroderma, Diffuse" by people in this website by year, and whether "Scleroderma, Diffuse" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Scleroderma, Diffuse" by people in Profiles.
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Histone Deacetylase 5 Is Overexpressed in Scleroderma Endothelial Cells and Impairs Angiogenesis via Repression of Proangiogenic Factors. Arthritis Rheumatol. 2016 12; 68(12):2975-2985.
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Gene expression changes reflect clinical response in a placebo-controlled randomized trial of abatacept in patients with diffuse cutaneous systemic sclerosis. Arthritis Res Ther. 2015 Jun 13; 17:159.
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Parvoviral infection of endothelial cells and stromal fibroblasts: a possible pathogenetic role in scleroderma. J Cutan Pathol. 2004 Jan; 31(1):43-50.