"Caspase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
| Descriptor ID |
D053148
|
| MeSH Number(s) |
D08.811.277.656.262.500.126.350.300 D08.811.277.656.300.200.126.350.300 D12.644.360.075.405.350.300 D12.776.476.075.405.350.300
|
| Concept/Terms |
Procaspase-3- Procaspase-3
- Procaspase 3
- Pro-Caspase-3
- Pro Caspase 3
|
Below are MeSH descriptors whose meaning is more general than "Caspase 3".
Below are MeSH descriptors whose meaning is more specific than "Caspase 3".
This graph shows the total number of publications written about "Caspase 3" by people in this website by year, and whether "Caspase 3" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 3 | 3 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 4 | 4 |
| 2008 | 0 | 5 | 5 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 1 | 3 | 4 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 3 | 3 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Caspase 3" by people in Profiles.
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Synthesis of 3-N-/O-/S-methyl-imidazo[1,2-a] pyridine derivatives for caspase-3 mediated apoptosis induced anticancer activity. Bioorg Chem. 2022 08; 125:105882.
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Novel Injury Scoring Tool for Assessing Brain Injury following Neonatal Hypoxia-Ischemia in Mice. Dev Neurosci. 2022; 44(4-5):394-411.
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Cyclooxygenase-2 deficiency attenuates lipopolysaccharide-induced inflammation, apoptosis, and acute lung injury in adult mice. Am J Physiol Regul Integr Comp Physiol. 2022 02 01; 322(2):R126-R135.
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Nimbolide induces cell death in T lymphoma cells: Implication of altered apoptosis and glucose metabolism. Environ Toxicol. 2021 Apr; 36(4):628-641.
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The differing pathophysiologies that underlie COVID-19-associated perniosis and thrombotic retiform purpura: a case series. Br J Dermatol. 2021 01; 184(1):141-150.
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A phase I study of AT-101, a BH3 mimetic, in combination with paclitaxel and carboplatin in solid tumors. Invest New Drugs. 2020 06; 38(3):855-865.
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Inhibition of histone deacetylase 6 attenuates intestinal inflammation and apoptosis in a rodent model of hemorrhagic shock. J Trauma Acute Care Surg. 2019 05; 86(5):874-880.
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Quercetin inhibits human metastatic ovarian cancer cell growth and modulates components of the intrinsic apoptotic pathway in PA-1?cell line. Chem Biol Interact. 2019 Feb 25; 300:91-100.
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Effect of melatonin on bovine theca cells in vitro. Reprod Fertil Dev. 2018 Mar; 30(4):643-650.
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Dendrimer-Based Selective Proteostasis-Inhibition Strategy to Control NSCLC Growth and Progression. PLoS One. 2016; 11(7):e0158507.