Fas-Associated Death Domain Protein
"Fas-Associated Death Domain Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.
|Fas-Associated Death Domain Protein
- Fas-Associated Death Domain Protein
- Fas-Associating Protein with Death Domain
- Fas Associating Protein with Death Domain
- MORT1 Protein
- Fas Associated Death Domain Protein
- FADD Protein, Fas-Associating
- FADD Protein, Fas Associating
- Fas-Associating FADD Protein
- Fas-Associating Protein FADD
- FADD, Fas-Associating Protein
- Fas Associating Protein FADD
Below are MeSH descriptors whose meaning is more general than "Fas-Associated Death Domain Protein".
Below are MeSH descriptors whose meaning is more specific than "Fas-Associated Death Domain Protein".
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Below are the most recent publications written about "Fas-Associated Death Domain Protein" by people in Profiles.
Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis. Mol Cell Biol. 2011 Sep; 31(18):3745-58.
Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice. Virology. 2002 Mar 01; 294(1):94-105.
Fas-induced apoptosis is mediated by activation of a Ras and Rac protein-regulated signaling pathway. J Biol Chem. 1996 Oct 18; 271(42):26389-94.