Glycogen Synthase Kinase 3 beta
"Glycogen Synthase Kinase 3 beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.
| Descriptor ID |
D000071679
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| MeSH Number(s) |
D05.500.117.875.500 D08.811.913.696.620.682.700.429.500.500 D08.811.913.696.620.682.700.646.625.500 D12.644.360.300.500.500 D12.776.476.081.875.500 D12.776.476.300.500.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Synthase Kinase 3 beta".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Synthase Kinase 3 beta".
This graph shows the total number of publications written about "Glycogen Synthase Kinase 3 beta" by people in this website by year, and whether "Glycogen Synthase Kinase 3 beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glycogen Synthase Kinase 3 beta" by people in Profiles.
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Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer. Gastroenterology. 2022 11; 163(5):1281-1293.e1.
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Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical ß-catenin-dependent mechanism. Sci Rep. 2020 06 29; 10(1):10578.
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Glycogen synthase kinase-3ß inhibition enhances myelination in preterm newborns with intraventricular hemorrhage, but not recombinant Wnt3A. Neurobiol Dis. 2018 10; 118:22-39.
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A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/ß-catenin signaling pathway. Tumour Biol. 2015 Sep; 36(9):7027-34.
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Elevated circulation levels of an antiangiogenic SERPIN in patients with diabetic microvascular complications impair wound healing through suppression of Wnt signaling. J Invest Dermatol. 2014 Jun; 134(6):1725-1734.
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Reg4-induced mitogenesis involves Akt-GSK3ß-ß-Catenin-TCF-4 signaling in human colorectal cancer. Mol Carcinog. 2014 Feb; 53 Suppl 1:E169-80.
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Light activation of the insulin receptor regulates mitochondrial hexokinase. A possible mechanism of retinal neuroprotection. Mitochondrion. 2013 Nov; 13(6):566-76.
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Costimulatory role of CXCR4 with pre-TCR and its crosstalk with PI3K in beta-selection of thymocytes. Sci Signal. 2010 Apr 27; 3(119):jc4.
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Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression. Blood. 2010 Mar 04; 115(9):1755-64.
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Cyclin D1 degradation is sufficient to induce G1 cell cycle arrest despite constitutive expression of cyclin E2 in ovarian cancer cells. Cancer Res. 2009 Aug 15; 69(16):6565-72.