"Gene Knockout Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during development to study the loss of function of a gene.
| Descriptor ID |
D055786
|
| MeSH Number(s) |
E05.393.335.750
|
| Concept/Terms |
Gene Knockout Techniques- Gene Knockout Techniques
- Gene Knockout Technique
- Knockout Technique, Gene
- Knockout Techniques, Gene
- Technique, Gene Knockout
- Techniques, Gene Knockout
- Gene Knockout
- Gene Knockouts
- Knockout, Gene
- Knockouts, Gene
- Gene Knock-Out Techniques
- Gene Knock-Out Technique
- Knock-Out Technique, Gene
- Knock-Out Techniques, Gene
- Technique, Gene Knock-Out
- Techniques, Gene Knock-Out
- Gene Knock Out
- Gene Knock Outs
- Knock Out, Gene
- Knock Outs, Gene
- Out, Gene Knock
- Outs, Gene Knock
- Gene Knock Out Techniques
|
Below are MeSH descriptors whose meaning is more general than "Gene Knockout Techniques".
Below are MeSH descriptors whose meaning is more specific than "Gene Knockout Techniques".
This graph shows the total number of publications written about "Gene Knockout Techniques" by people in this website by year, and whether "Gene Knockout Techniques" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 4 | 4 |
| 2014 | 0 | 3 | 3 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 3 | 3 |
| 2017 | 0 | 4 | 4 |
| 2018 | 0 | 4 | 4 |
| 2019 | 0 | 4 | 4 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Knockout Techniques" by people in Profiles.
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Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis. JCI Insight. 2022 01 25; 7(2).
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Genomic locus proteomic screening identifies the NF-?B signaling pathway components NF?B1 and IKBKG as transcriptional regulators of Ripk3 in endothelial cells. PLoS One. 2021; 16(6):e0253519.
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Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina. Biochem Biophys Res Commun. 2021 03 19; 545:8-13.
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Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 01 20; 109(2):241-256.e9.
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CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells. J Nat Prod. 2020 10 23; 83(10):3080-3092.
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PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21. JCI Insight. 2019 10 17; 4(20).
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CRISPR/Cas9 Knockout of Bak Mediates Bax Translocation to Mitochondria in response to TNFa/CHX-induced Apoptosis. Biomed Res Int. 2019; 2019:9071297.
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Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Rep. 2019 09 10; 28(11):2824-2836.e8.
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miR-23b and miR-27b are oncogenic microRNAs in breast cancer: evidence from a CRISPR/Cas9 deletion study. BMC Cancer. 2019 Jun 28; 19(1):642.
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Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice. J Lipid Res. 2019 03; 60(3):539-549.