"B7-2 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
| Descriptor ID |
D051940
|
| MeSH Number(s) |
D12.776.467.150.200 D12.776.543.095.200 D23.050.301.285.200 D23.529.168.200
|
| Concept/Terms |
B7-2 Antigen- B7-2 Antigen
- B7 2 Antigen
- B7-2 Costimulatory Molecule
- Costimulatory Molecule, B7-2
- B70 Costimulatory Molecule
- Costimulatory Molecule, B70
- Early T Cell Costimulatory Molecule 1
- CD86 Antigens
- Antigen, B7-2
- Antigen, B7 2
- Antigens, CD86
- CD86 Antigen
- Antigen, CD86
|
Below are MeSH descriptors whose meaning is more general than "B7-2 Antigen".
Below are MeSH descriptors whose meaning is more specific than "B7-2 Antigen".
This graph shows the total number of publications written about "B7-2 Antigen" by people in this website by year, and whether "B7-2 Antigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "B7-2 Antigen" by people in Profiles.
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Transcriptional Classification and Functional Characterization of Human Airway Macrophage and Dendritic Cell Subsets. J Immunol. 2017 02 01; 198(3):1183-1201.
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Co-stimulatory molecules as targets for treatment of lupus. Clin Immunol. 2013 Sep; 148(3):369-75.
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Role of fatty-acid synthesis in dendritic cell generation and function. J Immunol. 2013 May 01; 190(9):4640-9.
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Dendritic cell populations with different concentrations of lipid regulate tolerance and immunity in mouse and human liver. Gastroenterology. 2012 Oct; 143(4):1061-72.
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Defects in blood dendritic cell subsets in HIV-1 subtype c infected Indians. Indian J Med Res. 2010 Sep; 132:318-27.
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Ontogeny and phagocytic function of baboon lung dendritic cells. Immunol Cell Biol. 2009 Jul; 87(5):419-27.
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Prognosticators of melanoma, the melanoma report, and the sentinel lymph node. Mod Pathol. 2006 Feb; 19 Suppl 2:S71-87.