Low Density Lipoprotein Receptor-Related Protein-6
"Low Density Lipoprotein Receptor-Related Protein-6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An LDL-receptor related protein that combines with cell surface FRIZZLED RECEPTORS to form WNT PROTEIN-binding receptors. The protein plays an important role in the WNT SIGNALING PATHWAY during EMBRYONIC DEVELOPMENT and in regulation of vascular cell proliferation.
| Descriptor ID |
D060488
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| MeSH Number(s) |
D12.776.526.600 D12.776.543.750.710.450.500.600 D12.776.543.750.850.781
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| Concept/Terms |
Low Density Lipoprotein Receptor-Related Protein-6- Low Density Lipoprotein Receptor-Related Protein-6
- Low Density Lipoprotein Receptor Related Protein 6
- Low Density Lipoprotein Receptor-Related Protein 6
- Lipoprotein Receptor-Related Protein 6
- Lipoprotein Receptor Related Protein 6
|
Below are MeSH descriptors whose meaning is more general than "Low Density Lipoprotein Receptor-Related Protein-6".
Below are MeSH descriptors whose meaning is more specific than "Low Density Lipoprotein Receptor-Related Protein-6".
This graph shows the total number of publications written about "Low Density Lipoprotein Receptor-Related Protein-6" by people in this website by year, and whether "Low Density Lipoprotein Receptor-Related Protein-6" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Low Density Lipoprotein Receptor-Related Protein-6" by people in Profiles.
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Soluble very low-density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age-related macular degeneration. FASEB J. 2021 12; 35(12):e22058.
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Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina. Biochem Biophys Res Commun. 2021 03 19; 545:8-13.
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Interaction of PPARa With the Canonic Wnt Pathway in the Regulation of Renal Fibrosis. Diabetes. 2016 Dec; 65(12):3730-3743.
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Nanoparticle-mediated expression of a Wnt pathway inhibitor ameliorates ocular neovascularization. Arterioscler Thromb Vasc Biol. 2015 Apr; 35(4):855-64.
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Receptor heterodimerization as a novel mechanism for the regulation of Wnt/ß-catenin signaling. J Cell Sci. 2014 Nov 15; 127(Pt 22):4857-69.
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Antiangiogenic and antineuroinflammatory effects of kallistatin through interactions with the canonical Wnt pathway. Diabetes. 2013 Dec; 62(12):4228-38.
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Therapeutic potential of a monoclonal antibody blocking the Wnt pathway in diabetic retinopathy. Diabetes. 2012 Nov; 61(11):2948-57.