CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration.
Xu J, Morris LM, Michalakis S, Biel M, Fliesler SJ, Sherry DM, Ding XQ. CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration. Invest Ophthalmol Vis Sci. 2012 Mar 01; 53(3):1117-29.
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Animals
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Animals
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Arrestin
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Arrestin
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Blotting, Western
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Blotting, Western
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Cell Survival
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Cell Survival
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Cyclic Nucleotide-Gated Cation Channels
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Cyclic Nucleotide-Gated Cation Channels
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Electroretinography
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Electroretinography
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Heterotrimeric GTP-Binding Proteins
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Heterotrimeric GTP-Binding Proteins
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Immunohistochemistry
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Immunohistochemistry
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Membrane Proteins
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Membrane Proteins
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Mice
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Mice
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Mice, Inbred C57BL
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Mice, Inbred C57BL
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Mice, Knockout
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Mice, Knockout
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Microscopy, Electron
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Microscopy, Electron
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Presynaptic Terminals
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Presynaptic Terminals
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Retinal Cone Photoreceptor Cells
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Retinal Cone Photoreceptor Cells
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Retinal Degeneration
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Retinal Degeneration
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Retinal Rod Photoreceptor Cells
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Retinal Rod Photoreceptor Cells
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Rhodopsin
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Rhodopsin
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Rod Opsins
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Rod Opsins
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Transducin
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Transducin
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Vision, Ocular
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Vision, Ocular