Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats.

Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats. Br J Pharmacol. 2013 Apr; 168(8):1878-88.

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subject areas

Amidines
Animals
Blood Pressure
Cells, Cultured
Cerebrovascular Disorders
Cytochrome P-450 Enzyme System
Cytokines
Hydroxyeicosatetraenoic Acids
Male
Middle Cerebral Artery
NF-kappa B
Oxidative Stress
Rats
Rats, Inbred SHR
Rats, Inbred WKY
Reactive Oxygen Species
Vasomotor System

authors with profiles

Anna Csiszar
Stefano Tarantini
William Edmund Sonntag
Zoltan Ungvari