Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.
Csiszar A, Gautam T, Sosnowska D, Tarantini S, Banki E, Tucsek Z, Toth P, Losonczy G, Koller A, Reglodi D, Giles CB, Wren JD, Sonntag WE, Ungvari Z. Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H292-306.
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Age Factors
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Age Factors
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Aging
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Aging
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Animals
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Animals
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Brain
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Brain
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Caloric Restriction
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Caloric Restriction
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Cells, Cultured
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Cells, Cultured
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Crosses, Genetic
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Crosses, Genetic
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Endothelial Cells
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Endothelial Cells
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Gene Expression Profiling
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Gene Expression Profiling
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Gene Expression Regulation
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Gene Expression Regulation
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Inflammation
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Inflammation
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Inflammation Mediators
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Inflammation Mediators
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Male
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Male
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MicroRNAs
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MicroRNAs
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Microvessels
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Microvessels
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Mitochondria
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Mitochondria
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Neovascularization, Physiologic
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Neovascularization, Physiologic
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NF-E2-Related Factor 2
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NF-E2-Related Factor 2
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NF-kappa B
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NF-kappa B
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Oxidative Stress
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Oxidative Stress
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Phenotype
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Phenotype
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Rats
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Rats
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Rats, Inbred BN
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Rats, Inbred BN
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Rats, Inbred F344
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Rats, Inbred F344
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Transcription, Genetic
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Transcription, Genetic
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Transfection
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Transfection