Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses.
Wu W, Zhang W, Booth JL, Hutchings DC, Wang X, White VL, Youness H, Cross CD, Zou MH, Burian D, Metcalf JP. Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses. Respir Res. 2016 09 07; 17(1):111.
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Bronchi
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Bronchi
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Cells, Cultured
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Cells, Cultured
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DEAD Box Protein 58
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DEAD Box Protein 58
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DNA Methylation
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DNA Methylation
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DNA Modification Methylases
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DNA Modification Methylases
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Enzyme Inhibitors
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Enzyme Inhibitors
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Epigenesis, Genetic
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Epigenesis, Genetic
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Epithelial Cells
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Epithelial Cells
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Host-Pathogen Interactions
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Host-Pathogen Interactions
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Humans
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Humans
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Influenza A Virus, H1N1 Subtype
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Influenza A Virus, H1N1 Subtype
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Influenza, Human
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Influenza, Human
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Interferon-beta
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Interferon-beta
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Interferons
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Interferons
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Interleukins
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Interleukins
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Primary Cell Culture
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Primary Cell Culture
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Receptors, Immunologic
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Receptors, Immunologic
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RNA, Messenger
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RNA, Messenger
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Smoking
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Smoking
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Time Factors
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Time Factors
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Toll-Like Receptor 3
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Toll-Like Receptor 3