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Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice.
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Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice.
Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice. Toxicol Appl Pharmacol. 2015 Aug 15; 287(1):86-92.
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PubMed
subject areas
Alanine Transaminase
Animals
Antineoplastic Agents
Aptamers, Nucleotide
Aspartate Aminotransferases
Biomarkers
Chemical and Drug Induced Liver Injury
Complement C3a
Complement C5a
Cytokines
Dose-Response Relationship, Drug
Drug Administration Schedule
E-Selectin
Female
Injections, Intravenous
Kidney
Liver
Male
Mice, Inbred ICR
Necrosis
Risk Assessment
authors with profiles
Yan Daniel Zhao
Takemi Tanaka
Wajeeha Razaq