ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin a3ß1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells.

ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin a3ß1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells. Gastroenterology. 2020 02; 158(3):679-692.e1.

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subject areas

Adenocarcinoma
Adenocarcinoma
Animals
Animals
Antimetabolites, Antineoplastic
Antimetabolites, Antineoplastic
Cation Transport Proteins
Cation Transport Proteins
Cell Line, Tumor
Cell Line, Tumor
Cell Proliferation
Cell Proliferation
Cisplatin
Cisplatin
Deoxycytidine
Deoxycytidine
Drug Resistance, Neoplasm
Drug Resistance, Neoplasm
Equilibrative Nucleoside Transporter 1
Equilibrative Nucleoside Transporter 1
Fluorouracil
Fluorouracil
Gene Knockdown Techniques
Gene Knockdown Techniques
Humans
Humans
Integrin alpha3
Integrin alpha3
Integrin beta1
Integrin beta1
JNK Mitogen-Activated Protein Kinases
JNK Mitogen-Activated Protein Kinases
Male
Male
Mice
Mice
Mice, Nude
Mice, Nude
Neoplasm Metastasis
Neoplasm Metastasis
Neoplasm Transplantation
Neoplasm Transplantation
Pancreatic Neoplasms
Pancreatic Neoplasms
Phosphorylation
Phosphorylation
Signal Transduction
Signal Transduction
Spheroids, Cellular
Spheroids, Cellular
STAT3 Transcription Factor
STAT3 Transcription Factor
Survival Rate
Survival Rate
Zinc Finger E-box-Binding Homeobox 1
Zinc Finger E-box-Binding Homeobox 1

authors with profiles

Barish H Edil
Courtney Wayne Houchen
Jingxuan Yang
Kai Ding
Kar-Ming Fung
Michael Stuart Bronze
Min Li
Zhibo Yang
Zhijun Zhou