The antiviral efficacy of the murine alpha-1 interferon transgene against ocular herpes simplex virus type 1 requires the presence of CD4(+), alpha/beta T-cell receptor-positive T lymphocytes with the capacity to produce gamma interferon.
The antiviral efficacy of the murine alpha-1 interferon transgene against ocular herpes simplex virus type 1 requires the presence of CD4(+), alpha/beta T-cell receptor-positive T lymphocytes with the capacity to produce gamma interferon. J Virol. 2002 Sep; 76(18):9398-406.
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Animals
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Animals
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CD4-Positive T-Lymphocytes
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CD4-Positive T-Lymphocytes
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Genetic Therapy
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Genetic Therapy
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Herpesvirus 1, Human
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Herpesvirus 1, Human
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Interferon-alpha
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Interferon-alpha
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Interferon-gamma
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Interferon-gamma
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Keratitis, Herpetic
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Keratitis, Herpetic
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Mice
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Mice
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Plasmids
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Plasmids
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Receptors, Antigen, T-Cell, alpha-beta
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Receptors, Antigen, T-Cell, alpha-beta
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Tears
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Tears
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Transgenes
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Transgenes
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Vero Cells
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Vero Cells
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Virus Replication
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Virus Replication